Research theme for competitive and other funds (11):
2023 - 2028 Challenge to elucidation of pathology based on the discovery of protein pyrrolation
2022 - 2025 Paradigm shift in polyphenol function: Formation of oxidation-specific ligands and biological defense response
2017 - 2023 酸化脂質をターゲットとした疾患メカニズム解明および創薬基盤研究
2017 - 2022 Life science basis of short-lived reactive species originated from foods
2014 - 2019 Oxygen biology: a new criterion for integrated understanding of life
2014 - 2019 Formation and regulation of ligand signals associated with accepting and activating molecular oxygen
2016 - 2018 Redox-metabolomic analysis of histidine and imidazole dipeptides
2014 - 2017 Basic studies on anti-inflammatory lipid mediators
2009 - 2014 Sensor mechanism of lipophilic ligands
2008 - 2014 Signaling Functions of Reactive Oxygen Species
2008 - 2013 Chemical Biology of Reactive Oxygen Species Ligand Receptor Regulation
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Papers (351):
Haruka Sei, Naoya Hirade, Kohei Kamiya, Fumie Nakashima, Jun Yoshitake, Keiko Kano, Emi Mishiro-Sato, Ryosuke Kikuchi, Koji Uchida, Takahiro Shibata. Isocitrate dehydrogenase 1 upregulation in urinary extracellular vesicles from proximal tubules of type 2 diabetic rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024. 38. 10. e23688
Baiyu Qiu, Fereshteh Zandkarimi, Anjali Saqi, Candace Castagna, Hui Tan, Miroslav Sekulic, Lisa Miorin, Hanina Hibshoosh, Shinya Toyokuni, Koji Uchida, et al. Fatal COVID-19 pulmonary disease involves ferroptosis. Nature communications. 2024. 15. 1. 3816-3816
Atsushi Morimoto, Nobumasa Takasugi, Yuexuan Pan, Sho Kubota, Naoshi Dohmae, Yumi Abiko, Koji Uchida, Yoshito Kumagai, Takashi Uehara. Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signaling. The Journal of biological chemistry. 2024. 300. 3. 105679-105679
Marie-Julie Nokin, Florence Durieux, Paul Peixoto, Barbara Chiavarina, Olivier Peulen, Arnaud Blomme, Andrei Turtoi, Brunella Costanza, Nicolas Smargiasso, Dominique Baiwir, et al. Correction: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis. eLife. 2024. 13
Yusuke Anan, Masanori Itakura, Tatsuya Shimoda, Kosuke Yamaguchi, Peng Lu, Koji Nagata, Jinhua Dong, Hiroshi Ueda, Koji Uchida. Molecular and structural basis of anti-DNA antibody specificity for pyrrolated proteins. Communications biology. 2024. 7. 1. 149-149
Fumie Nakashima, Takahiro Shibata, Koji Uchida. Contribution of Covalent Modification of Food-derived Compounds to Anti-inflammatory Activities. Nippon Eiyo Shokuryo Gakkaishi. 2024. 77. 2. 125-130
Anti-inflammatory function of advanced glycation end products(AGEs). 2022. 40. 2637-2640
山口公輔, 板倉正典, 北澤麗磨, LIM Sei Young, 永田宏次, 柴田貴広, 赤川貢, 内田浩二. Structural analysis of polyphenol-modified proteins and elucidation of their interaction mechanisms with histones. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
Yuji Naito, Koji Uchida, Shinya Toyokuni. The new era for redox research. Free Radical Research. 2020. 54. 11-12. 787-789