Research theme for competitive and other funds (11)：
2023 - 2028 Challenge to elucidation of pathology based on the discovery of protein pyrrolation
2022 - 2025 Paradigm shift in polyphenol function: Formation of oxidation-specific ligands and biological defense response
2017 - 2023 酸化脂質をターゲットとした疾患メカニズム解明および創薬基盤研究
2017 - 2022 Life science basis of short-lived reactive species originated from foods
2014 - 2019 Oxygen biology: a new criterion for integrated understanding of life
2014 - 2019 Formation and regulation of ligand signals associated with accepting and activating molecular oxygen
2016 - 2018 Redox-metabolomic analysis of histidine and imidazole dipeptides
2014 - 2017 Basic studies on anti-inflammatory lipid mediators
2009 - 2014 Sensor mechanism of lipophilic ligands
2008 - 2014 Signaling Functions of Reactive Oxygen Species
2008 - 2013 Chemical Biology of Reactive Oxygen Species Ligand Receptor Regulation
Show all
Papers (356)：
Kosuke Yamaguchi, You-Yun Hu, Kaito Kawajiri, Masanori Itakura, Fumie Nakashima, Takahiro Shibata, Koji Uchida. Adductome-based identification of lysine mono-methylation as a key post-translational protein modification in autoimmune diseases. Journal of Biological Chemistry. 2025. 110684-110684
Yuma Saimoto, Daiki Kusakabe, Kazushi Morimoto, Yuta Matsuoka, Eisho Kozakura, Nao Kato, Kayoko Tsunematsu, Tomohiro Umeno, Tamiko Kiyotani, Shota Matsumoto, et al. Lysosomal lipid peroxidation contributes to ferroptosis induction via lysosomal membrane permeabilization. Nature Communications. 2025. 16. 1. 3554-3554
Masanori Itakura, Kosuke Yamaguchi, Koji Uchida. Moonlight function of antioxidants. Bioscience, Biotechnology, and Biochemistry. 2025. 89. 2. 187-192
Haruka Sei, Naoya Hirade, Kohei Kamiya, Fumie Nakashima, Jun Yoshitake, Keiko Kano, Emi Mishiro-Sato, Ryosuke Kikuchi, Koji Uchida, Takahiro Shibata. Isocitrate dehydrogenase 1 upregulation in urinary extracellular vesicles from proximal tubules of type 2 diabetic rats. FASEB Journal. 2024. 38. 10. e23688
Baiyu Qiu, Fereshteh Zandkarimi, Anjali Saqi, Candace Castagna, Hui Tan, Miroslav Sekulic, Lisa Miorin, Hanina Hibshoosh, Shinya Toyokuni, Koji Uchida, et al. Fatal COVID-19 pulmonary disease involves ferroptosis. Nature Communications. 2024. 15. 1. 3816-3816
