Rchr
J-GLOBAL ID:200901022317058316
Update date: Aug. 30, 2024
Ohya Yoshikazu
オオヤ ヨシカズ | Ohya Yoshikazu
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://ps.k.u-tokyo.ac.jp/top.html
Research field (1):
Genetics
Research keywords (2):
酵母分子遺伝学
, Genetic studies of molecular aspects in yeast
Research theme for competitive and other funds (49):
- 2022 - 2025 Morphological profiling for the development of antifungal agents
- 2020 - 2023 Intelligent directed evolution: technology development and application to yeast
- 2019 - 2022 Global study of haploinsufficient genes in Saccharomyces cerevisiae
- 2015 - 2018 Linking novel bioactive compounds to their targets and pathways using chemical genomics and morphological profiling
- 2015 - 2018 Elucidation of the working principle of cells based on high dimensional phenotyping
- 2012 - 2015 Yeast Phenome analysis with super-hidimensional morphological profiling
- 2007 - 2012 出芽酵母を利用した創薬シード化合物の探索
- 2007 - 2012 Cell cycle regulation of cell morphology and cell size
- 2009 - 2011 Morphological Profiling in Saccharomyces cerevisiae and Development of high-content imaging techniques
- 2007 - 2008 Cell Cycle Regulation of Cell Morphology in Saccharomyces cerevisiae
- 2005 - 2006 Molecular Mechanism of Cell Wall Integrity Checkpoint
- 2004 - 2005 Study of cell morphogenesis that is coupled with cell division cycle
- 2001 - 2005 Cell Cycle Start Control
- 2000 - 2005 Cell Cycle Control
- 2002 - 2004 カルモデュリンの情報伝達モード切り替えスイッチ仮説の検証
- 2002 - 2004 Multifunctional molecular switch essential for cell morphogenesis
- 1998 - 2002 Homing directed by VDE endonuclease in Saccharomyces cerevisiae
- 2002 - 細胞形態の自動認識プログラムを用いた出芽酵母遺伝子破壊株の網羅的解析
- 1999 - 2001 Multifunctional molecular switch essential for cell morphogenesis
- 1999 - 2000 A Comprehensive Study on Intrusion and Cooperation of Genomes
- 1999 - 2000 TRANSLATION SYSTEM WITH COMPLEXITY
- 1997 - 1999 低分子量G蛋白質による細胞の増殖、運動の制御機構
- 1996 - 1999 Dynamics of chromosome partition apparatus
- 1999 - シグナル伝達の立場から捉えた細胞周期調節機構の研究
- 1997 - 1998 細胞壁形成がG2/M進行をコントロールする分子機構
- 1997 - 1998 A Crossdisciplinary Study on the Benefits of Sexual Reproduction
- 1996 - 1998 Study of multifunctional signalling proteins implicated in cell proliferation
- 1997 - 細胞の形態形成に関与する多機能分子スイッチの調節機構の研究
- 1996 - 1996 酵母微小管集合中心の高次機能の解析
- 1995 - 1996 Molecular biological studies on the mechanism of self protein splicing in the yeast VMA1 protozyme
- 1995 - 1995 多機能蛋白質の分子遺伝的研究
- 1995 - 1995 細胞周期を調節する多機能タンパク質の遺伝学的研究
- 1994 - 1994 遺伝子内で相補するカルモデュリン変異の分子生物学的研究
- 1994 - 1994 細胞周期を調節する多機能タンパク質の遺伝学的研究
- 1991 - 1991 液胞膜H^+-ATPaseの生合成・細胞内輸送・高次構造構築機構の研究
- 1991 - 1991 Ca^<2+>/カルモデュリンによる核分裂制御機構の解析
- 1990 - 1990 酵母液胞膜H^+-ATPaseの分子遺伝学的研究
- 1990 - 1990 Ca^<2+>/カルモデュリンによる核分裂制御機構の解析
- 1989 - 1990 酵母におけるERーゴルジ間輸送の分子機構
- 1989 - 1989 カルシウム-カルモデユリン情報伝達系に関する分子生理学的研究
- 1988 - 1989 Mechanisms of cell cycle control by calcium ion.
- 1988 - 1988 酵母カルモジュリンの生理機能に関する分子遺伝学的研究
- 1988 - 1988 カルシウム-カルモジュリン情報伝達系に関する分子生理学的研究
- 1987 - 1987 酵母カルモジュリンの生理機能に関する分子遺伝学的研究
- 1987 - 1987 Ca^<2+>による酵母細胞複製
- 1986 - 1986 酵母カルモジュリンの生理機能に関する分子生物学的研究
- Study of cell morphogenesis in yeast cells
- Study of a yeast Ca2+-binding protein, Calmodulin
- Study of Ca2+ homeostasis in Saccharomyces cerevisiae
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Papers (119):
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Farzan Ghanegolmohammadi, Wei Liu, Tingtao Xu, Yuze Li, Shinsuke Ohnuki, Tetsuya Kojima, Kaori Itto-Nakama, Yoshikazu Ohya. Rational selection of morphological phenotypic traits to extract essential similarities in chemical perturbation in the ergosterol pathway. Scientific Reports. 2024. 14. 1
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Yoshikazu Ohya, Farzan Ghanegolmohammadi, Kaori Itto-Nakama. Application of unimodal probability distribution models for morphological phenotyping of budding yeast. FEMS Yeast Research. 2024. 24
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Norapat Klinkaewboonwong, Shinsuke Ohnuki, Tomoya Chadani, Ikuhisa Nishida, Yuto Ushiyama, Saki Tomiyama, Atsuko Isogai, Tetsuya Goshima, Farzan Ghanegolmohammadi, Tomoyuki Nishi, et al. Targeted Mutations Produce Divergent Characteristics in Pedigreed Sake Yeast Strains. Microorganisms. 2023. 11. 5. 1274-1274
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Kaori Itto-Nakama, Shun Watanabe, Shinsuke Ohnuki, Naoko Kondo, Ryota Kikuchi, Toru Nakamura, Wataru Ogasawara, Ken Kasahara, Yoshikazu Ohya. Prediction of ethanol fermentation under stressed conditions using yeast morphological data. Journal of Bioscience and Bioengineering. 2023. 135. 3. 210-216
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Mika Hayashi, Shinsuke Ohnuki, Yating Tsai, Naoko Kondo, Yuqi Zhou, Hongqian Zhang, Natsumi Tiffany Ishii, Tianben Ding, Maik Herbig, Akihiro Isozaki, et al. Is AI essential? Examining the need for deep learning in image-activated sorting of Saccharomyces cerevisiae. Lab on a Chip. 2023
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MISC (101):
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Jeff S. Piotrowski, Sheena C. Li, Raamesh Deshpande, Scott W. Simpkins, Justin Nelson, Yoko Yashiroda, Jacqueline M. Barber, Hamid Safizadeh, Erin Wilson, Hiroki Okada, et al. Functional annotation of chemical libraries across diverse biological processes (vol 13, pg 982, 2017). NATURE CHEMICAL BIOLOGY. 2017. 13. 12. 1286-1286
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Designer Yeasts for Bio-ethanol Production. Bio industry. 2014. 31. 1. 58-64
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Watanabe Daisuke, Nogami Satoru, Ohya Yoshikazu, Kanno Yoichiro, Zhou Yan, Akao Takeshi, Shimoi Hitoshi. 1Jp11 Ethanol Fermentation Driven by Elevated Expression of G1 Cyclin CLN3 in Sake Yeast. 2011. 63. 64-64
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Takahiro Negishi, Yoshikazu Ohya. The cell wall integrity checkpoint: coordination between cell wall synthesis and the cell cycle. YEAST. 2010. 27. 8. 513-519
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KOBAYASHI TOMOHIDE, OGAWA HAYATO, WATANABE MACHIKA, ONUKI SHINSUKE, NOGAMI SATORU, KOZONE IKUKO, UEDA JUN'YA, TAKAGI MOTOKI, SHIN'YA KAZUO, OHYA YOSHIKAZU. 出芽酵母細胞の形態を細長く変化させる新規化合物JBIR-19の作用機構の解明. 生化学. 2010. ROMBUNNO.3P-1169
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Education (4):
- - 1984 The University of Tokyo
- - 1984 The University of Tokyo Graduate School, Division of Science
- - 1982 The University of Tokyo Faculty of Science
- - 1982 The University of Tokyo Faculty of Science
Professional career (1):
Awards (1):
Association Membership(s) (4):
日本植物学会
, 日本分子生物学会
, 日本生化学会
, 日本遺伝学会
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