Fukata Yuko

フカタユウコ | Fukata Yuko

Affiliation and department：
Homepage URL (1)： https://www.med.nagoya-u.ac.jp/neuropharmacology/fukata/

Research field (1)： Neuroscience - general

Research keywords (21)：包括脳ネットワーク , 生化学 , グルタミン酸受容体 , 神経科学 , AMPA受容体 , シナプス , てんかん , リガンド・受容体 , 質量分析 , 神経シナプス , 膜蛋白質 , 蛋白質複合体 , シナプス伝達 , LGI1 , 脂質修飾 , 酵素 , パルミトイル化 , 超解像顕微鏡 , G蛋白質 , GFPイメージング , 細胞生物学

Research theme for competitive and other funds (16)：

2022 - 2025 液-液相分離によるシナプス-ナノ構築の制御機構の解明
2021 - 2024 遺伝学的知見に基づく新たなてんかん治療戦略の開発
2019 - 2022 Proteomic analysis with high spatiotemporal resolution at the synapse
2019 - 2022 Neuron type-specific regulatory mechanisms of the synapse
2016 - 2018 Optogenetic manipulation of protein palmitoylation for synapse organization

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Papers (101)：

Yuri Miyazaki, Takeshi Otsuka, Yoko Yamagata, Toshihiro Endo, Makoto Sanbo, Hiromi Sano, Kenta Kobayashi, Hiroki Inahashi, Hans-Christian Kornau, Dietmar Schmitz, et al. Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity. Cell Reports. 2024. 113634-113634
Lin Chen, Yuko Fukata, Kazuyoshi Murata. In situ cryo-electron tomography: a new method to elucidate cytoplasmic zoning at the molecular level. Journal of biochemistry. 2023
Lenka Nosková, Yuko Fukata, Viktor Stránecký, Jana Šaligová, Oxana Bodnárová, Mária Giertlová, Masaki Fukata, Stanislav Kmoch. ADAM22 ethnic-specific variant reducing binding of membrane-associated guanylate kinases causes focal epilepsy and behavioural disorder. Brain Communications. 2023. 5. 6
Xu Zhang, Jun-Ichi Kira, Hidenori Ogata, Tomohiro Imamura, Mikio Mitsuishi, Takayuki Fujii, Masaki Kobayashi, Kazuo Kitagawa, Yukihiro Namihira, Yusuke Ohya, et al. Anti-LGI4 Antibody Is a Novel Juxtaparanodal Autoantibody for Chronic Inflammatory Demyelinating Polyneuropathy. Neurology - Neuroimmunology Neuroinflammation. 2023. 10. 2. e200081
Yoko Niki, Naoko Adachi, Masaki Fukata, Yuko Fukata, Shinichiro Oku, Chieko Makino-Okamura, Seiji Takeuchi, Kazumasa Wakamatsu, Shosuke Ito, Lieve Declercq, et al. S-palmitoylation of tyrosinase at cysteine500 regulates melanogenesis. Journal of Investigative Dermatology. 2022

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MISC (15)：

横井紀彦, 深田優子, 深田正紀. てんかん発症を抑制するためのLGI1-ADAM22タンパク質複合体の量的制御機構. 生化学. 2023. 95. 3. 384-388
Masaki Fukata, Norihiko Yokoi, Yuko Fukata. Acyl-PEGyl exchange gel-shift (APEGS) assay for palmitoylation quantification. Electrophoresis Letters. 2021. 65. 2. 41-45
深田正紀, 横井紀彦, 平田哲也, 深田優子. zDHHC パルミトイル化酵素と ABHD17 脱パルミトイル化酵素. 膜タンパク質工学ハンドブック. 2020. 316-323
平野瑶子, 宮﨑裕理, 深田正紀, 深田優子. てんかん関連リガンド・受容体 LGI1・ADAM22. 膜タンパク質工学ハンドブック. 2020. 357-365
平田哲也, 深田優子, 深田正紀. パルミトイル化修飾酵素を軸とした神経機能研. 生化学. 2018. 90. 2. 125-137

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Education (3)：

1997 - 2000 Nara Institute of Science and Technology
1995 - 1997 Nara Institute of Science and Technology
1988 - 1994 Kobe University School of Medicine Faculty of Medicine

Work history (10)：

2023/08 - 現在 Nagoya University Graduate School of Medicine Division of Molecular and Cellular Pharmacology Associate Professor
2023/08 - 2024/03 National Institutes of Natural Sciences, National Institute for Physiological Sciences Division of Membrane Physiology Associate Professor
2007/12 - 2023/07 National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS) Division of Membrane Physiology Associate Professor
2007/10 - 2011/03 Japan Science and Technology Agency
2007/06 - 2007/09 National Institute for Physiological Sciences

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Awards (2)：

2009 - 平成21年度文部科学大臣表彰若手科学者賞
2007 - Human Frontier Science Program Organization Career Development Awards

Association Membership(s) (2)：

THE JAPAN NEUROSCIENCE SOCIETY , Society for Neuroscience

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