2023 - 2027 Challenge to periodontal tissue regeneration and refractory immune diseases based on amelogenin-CRP78 complex
2022 - 2025 歯周病と動脈硬化-微細炎症合併日本人型軽度肥満モデルでの検討
2021 - 2024 歯肉増殖症や肥満に関わる新規分子SPOCK1のシグナリング経路の探索
2020 - 2024 New therapeutic strategy for periodontal disease targeting exosomal miRNA derived from GMSCs.
2020 - 2024 統合オミクス解析を介した糖尿病性歯周炎の病態解明を目指す国際共同研究
2019 - 2022 The role of inflammatory induced Xaf1 in pancreatic beta cells~correlation with periodontitis
2018 - 2022 The elucidation of the pathophysiology of gingival overgrowth.
2019 - 2021 Development of preventive strategy against periodontitis using SPOCK-1
2017 - 2020 Development of new periodontal treatment targeting using GMSC-derived exosomes
2017 - 2020 Development of a novel periodontal tissue regenarative therapy that induces resolution of inflammation and tissue remodeling
2016 - 2019 Role of complement factor B on insulin resistance-related disease
2016 - 2019 Japan-China Joint Epidemiological Survey of Tibetan Elderly on Correlation between Oral Health and Cognitive Functions
2017 - 2019 歯周医学の新展開~歯周炎症とエネルギー代謝の連関
2016 - 2019 New direction in periodontal medicine: Association of periodontal inflammation with energy metabolism
2015 - 2018 the unravelling of the role of cathepsin in gingival overgrowth
2014 - 2017 Molecular basis of amelogenin-induced periodontal tissue regeneration
2014 - 2017 The effects of Spry2 on the differentiation of Pg LPS-stimulated macrophages.
2014 - 2017 Molecular mechanism of sphingosine-1-phosphate-modulated MSC differentiation for hard tissue regenerative therapy
2013 - 2016 Analyzing the unknown potential of dental pulp cells, and aiming to the new clinical development of regenerative therapy of dental pulp tissue
2016 - 2016 歯髄細胞由来TNF誘導因子(DPTIF)受容体の探索研究
2014 - 2016 口腔から健康長寿を支えるプロジェクト推進に向けた研究拠点構築プログラム
2014 - 2016 Investigation for the receptor of dental pulp cell-derived tumor necrosis factor-alpha inducing factor (DPTIF)
2013 - 2016 臓器固有細胞-浸潤炎症細胞間相互作用から捉える歯周医学の分子基盤
2013 - 2016 臓器固有細胞-浸潤炎症細胞間相互作用から捉える歯周医学の分子基盤
2013 - 2015 臓器固有細胞-浸潤炎症細胞間相互作用から捉える歯周医学の分子基盤
2011 - 2014 Study on the elucidation and prevention for cardiovascular disorder by HACEK group oral bacteria
2009 - 2014 Basic study to unify periodontal medicine and anti-aging medicine
2011 - 2013 Analysis of patients with gingival hyperplasia and hypertrichosis
2011 - 2013 マクロファージと共存する歯髄細胞で発現変動する分子群の網羅的解析
2010 - 2012 A retrospective cohort study of the mutual association between periodontal etiology and metabolic syndrome
2009 - 2011 Potential pain-releasing action of PAF antagonists in neuropathic pain animal models and the mechanisms of action
2008 - 2010 Development of adhesive system with capacity of self-repair applied by Sr-CaPO4 complex
2008 - 2009 栄養素と齲蝕感受性の関連性の解明
2007 - 2009 Integrated functional analysis of non-coding RNA in periodontal diseases -Focusing on interaction between bacteria and host
2007 - 2008 Assessment of optimal irradiation parameters of adhesive properties of resinous materials and development of poly-acid based adhesives for lased dentin
2006 - 2007 A study for the involvement of IL-22 in the pathogenesis of periodontal diseases
2005 - 2007 Elucidation of mechanism on periodontal medicine liver inflammatory responses against periodontlal infection
2005 - 2006 カテプシン-Lプロモーターの薬剤応答配列を標的とした歯肉増殖症の治療法開発
2005 - 2006 The effect on dentin-pulp complex by FIP-2 isolated from rat wounded pulp
2003 - 2006 X-ray Crystal Structural Analysis of Bacterial Iron Binding Protein and Development for New Antibiotics
2003 - 2005 Clinical research for relationship between periodontal disease and systemic disease
2002 - 2005 Gene Therapy for Periodontal Diseases -Regulation of host response by local gene delivery-
2004 - 2004 歯周靭帯細胞における機械的ストレス応答性遺伝子のグルーピングと転写機構
2003 - 2004 A basic studies to develop the immune therapy for periodontal diseases by employing glycolipids derived from periodontal bacteria as antigens.
2001 - 2004 Three-dimensional structural analysis and development of new inhibitors of glucan synthetase produced by cariogenic oral streptococci
2002 - 2003 歯周炎をインスリン抵抗性症候群に包括するための研究
2002 - 2003 Role of a novel transcription factor for TNF-α, LITAF, on the pathogenesis of periodontitis
2001 - 2003 Study on the pathogenesis of drug-induced gingival overgrowth -A study with deficient mice
2001 - 2003 Study of preventive and early treatment for periodontitis and pulaiti s on person of advanced years
2002 - 2002 歯周病細菌のポストゲノム研究の新展開に向けて
2000 - 2001 歯周病の発症と進行に関わる交叉免疫応答を誘導する抗原蛋白
2000 - 2001 Factor for induction of root resorption
2000 - 2001 Microbiological examination for periodontal therapy
2000 - 2001 Periodontal Treatment by Regulation of Novel TNF-α Transcription Factor in Monocytes
2000 - 2001 A study on the establishment of periodontal treatment for patients with insulin resistant diabetes mellitus.
1999 - 2000 Molecular Epidemiological Study of Periodontopathic Bacteria in Periodontal Diseases
1998 - 2000 Molecular biology of pathological conditions and diagnosis in dental pulp disorder and periodontal disease.
1999 - 1999 う蝕・歯周病予防ワクチン開発に向けての新たな戦略
1998 - 1999 Study on the pathogenesis of periodontal disease in patients with Down's syndrome
1997 - 1999 Study of aging system in Pulpal and periodontal tissue
1998 - 1998 歯周病治療から内科疾患治療へのアプローチ
1997 - 1998 Study on the Iron-Acquisition Mechanism of Periodontal Bacteria
1997 - 1998 Basic studies on adaptation the immune therapy to the patients with periodontal diseases by using synthetic peptides as an immunogen
1996 - 1998 Study on the control of periodontal ligament fibroblast functions by transforming growth factor
1996 - 1997 Regulation of osteogenic function of periodontal ligament fibroblast by 1d, 25-dihydroxy vitamin D3 receptor inducing factor.
1996 - 1997 Synthetic Studies of Age Changes on Priodontium
1994 - 1996 Study on the calcification by periodental ligament fibroblasts in the periodonta regeneration
生体の老化に関する研究
歯周組織の再生に関する研究
歯周病の易感染性に関する研究
Study on an aging
Study on regeneration of periodontal tissue
Study on susceptibility to periodontal disease
Show all
Papers (411)：
Kohei Sato, Takanori Shinjo, Tatsuro Zeze, Al-Kafee Ahmed, Honoka Otsuka, Hisashi Yokomizo, Naoichi Sato, Mio Imagawa, Yuki Nishimura, Naoaki Ryo, et al. Glomerular Haematopoietic Prostaglandin D Synthase-Prostaglandin D2 Axis Contributes to the Periodontitis-Related Exacerbation of Diabetic Nephropathy in KK-Ay Mice. Journal of clinical periodontology. 2025
Miyu Shida, Terukazu Sanui, Karen Yotsumoto, Jinfeng Li, Mwannes Ahmad, Meng Xiao, Ziyu Wang, Chikako Hayashi, Yuki Nishimura, Takanori Shinjo, et al. Prolonged skin allograft survival by rM180 amelogenin in a murine skin transplantation model. Frontiers in immunology. 2025. 16. 1663437-1663437
Takanori Shinjo, Fusanori Nishimura. The bidirectional association between diabetes and periodontitis, from basic to clinical. Japanese Dental Science Review. 2024
Mohammed Fouad Zakaria, Hiroki Kato, Soichiro Sonoda, Kenichi Kato, Norihisa Uehara, Yukari Kyumoto-Nakamura, Mohammed Majd Sharifa, Liting Yu, Lisha Dai, Haruyoshi Yamaza, et al. NaV1.1 contributes to the cell cycle of human mesenchymal stem cells by regulating AKT and CDK2. Journal of Cell Science. 2024
Mhd Fouad Zakaria, Soichiro Sonoda, Hiroki Kato, Lan Ma, Norihisa Uehara, Yukari Kyumoto-Nakamura, M Majd Sharifa, Liting Yu, Lisha Dai, Erika Yamauchi-Tomoda, et al. Erythropoietin receptor signal is crucial for periodontal ligament stem cell-based tissue reconstruction in periodontal disease. Scientific reports. 2024. 14. 1. 6719-6719
Diabetes and periodontitis
Springer Singapore 2017
歯根膜の組織修複における分子制御と加令に伴う変化
1996
Genetic control and age dependence of periodontal ligament repair
The biological mechanisms of tooth eruption, resorption and replacement by implants. Harvard Society for the Advancement of Orthodontics. 1996
歯周組織修復における細胞分子生物学
1994
Cellular and Molecular Biology of Periodontal Wound Healing
Periodontal Regeneration. current Status and Directions Quintessence Publishing Co. 1994
1999/06 - International Academy of Periodontology The First Award in Basic Research Category of 7Th Meeting of The International Academy of Periodontology
1999 - 日本歯科保存学会 日本歯科保存学会奨励賞
Association Membership(s) (9)：
Japanese Society of Diabetic Complications
, Japan Diabetes Society
, 国際歯科研究会
, Japanese Society of Periodontology
, Japanese Society of Conservative Dentistry
, Japan Dental Education Association
, International Academy of Periodontology
, 日本病態栄養学会
, Japan Society of Metabolism and Clinical Nutrition
