Baba Hideo

2018 - 2021 Fusobacterium nucleatum Confers Chemoresistance by Modulating Autophagy in Esophageal Squamous Cell Carcinoma

2018 - 2020 Comprehensive analysis of gut microbiome and sarcopenia in gastrointestinal cancers

2015 - 2020 Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells

2016 - 2019 Investigation of novel molecular targeted therapeutics based on epigenetics in colorectal cancer.

2016 - 2018 Identification of the molecular mechanism underlying cancer stem cell regulation via arachidonic cascade

2014 - 2018 Prospective study of acceptability of surgical performance by medical student in clinical education

2014 - 2017 The identification of novel microRNAs regulating cancer stem cell properties and the clinical application to therapeutic strategy in gastrointestinal cancer

2014 - 2017 The mechanism of liver atrophy after portal vein hypoperfusion and therapeutic method using LSKL peptide

2013 - 2016 Analysis for the effect of C5a receptor on cancer cell and development for targeted therapeutic strategy to C5a receptor

2013 - 2016 Development of FGFR2 targeting therapy for the patients with EGJ adenocarcinoma.

2013 - 2015 Changes in expression levels of ERCC1, DPD, and VEGFA mRNA after first-line chemotherapy of metastatic colorectal cancer

2011 - 2013 Global analysis of genomic alterations associated with AKT and ERK pathway in esophageal squamous cell carcinoma

2011 - 2013 p53 and autophagy in colorectal cancer : function mechanism and Therapeutic applications

2011 - 2012 The development of novel clinical education system using Augmented Realitytechnology

2011 - 2012 The identification of miR-gene pathway regulating the sensitivity of platinum agentsfor gastric cancer and its clinical applicatio

2011 - 2012 The elucidation of the novel microRNA-gene pathway regulating the peritoneal dissemination in gastric cancer

2011 - 2012 Can mTOR become target of the molecular target therapy in esophagus squamous cell carcinoma?

2010 - 2012 Clinical significance of serum exosomal micro RNA in human esophageal squamous cellcarcinoma

2010 - 2012 Analysis of the new joint protein receptor of PSTI

2010 - 2012 The crosstalk between cholesterol synthesis pathway and TGF-beta in pancreatic cancer

2009 - 2011 Effect of DNA methylation on the regulation of microRNA in squamous cell carcinoma of the esophagus

2009 - 2011 Prevention of HCC recurrence by Radiofrequency ablation with Glypican-3 epitope peptide injection to tumor site

2009 - 2011 Significance of serum bile acid level to predict the effective functional hypertrophy of the nonembolized liver after portal vein embolization

2008 - 2010 Clinical significance of Laminin-332 and its potential as a therapeutic target

2008 - 2010 Analysis of autophagy in cancer and new strategies for cancer therapy.

2007 - 2009 Development of Novel Therapy by miRNA Targeting for Gastroenterological Cancer

2007 - 2009 Prospective non-randomized trial comparing esophagectomy versus definitive chemoradiation for potentially-resectable esophageal cancer : multi-institutional study

2007 - 2009 Identify the mechanism of invasion and metastasis of pancreatic cancer and development of novel treatment starategy.

2007 - 2008 Elucidation of the mechanism in acute pancreatitis development using gene-manipulated mice

2006 - 2007 Analysis of negative regulation of EMT by receptor tyrosine kinase, DDR1

2006 - 2007 Basic research of the molecular targeting therapy against m-calpain in mitosis

2006 - 2007 The analysis of molecular mechanism for IRS-1 ubiquitination by nitric oxide

2005 - 2006 Prediction of chemoradiosensitivity of esophageal cancer

2001 - 2004 Detection and clinical application of circulating cancer cells, using highy pricise cancer cell determination system

2002 - 2003 Basic research on antlangiogenic drug to prevent metastasls of gastric cancer

1993 - 1993 Lonidamineと温熱併用による制癌剤耐性の克服に関する研究

1991 - 1993 Chemosensitivity test based on the intracellular level of free calcium