Kubota Toshiaki

クボタトシアキ | Kubota Toshiaki

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.med.oita-u.ac.jp/ganka/index.html

Research field (1)： Ophthalmology

Research keywords (5)：血管新生 , 落屑症候群 , 網膜硝子体 , 緑内障 , glaucoma; vitreoretina; exfoliation; angiogenesis

Research theme for competitive and other funds (8)：

1996 - 2020 Vitreo-retina Surgery
1990 - 2020 Glaucoma
2006 - 2008 緑内障の病因に関する細胞生物学的研究-ステロイド緑内障からのアプローチ-
1996 - 1998 落屑症候群の緑内障発病機序に関する研究
1995 - 1996 落屑症候群の病因に関する共同研究

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Papers (39)：

Kusunose N, Akamine T, Kobayashi Y, Yoshida S, Kimoto K, Yasukochi S, Matsunaga N, Koyanagi S, Ohdo S, Kubota T. Contribution of the clock gene DEC2 to VEGF mRNA upregulation by modulation of HIF1α protein levels in hypoxic MIO-M1 cells, a human cell line of retinal glial (Müller) cells. Japanese journal of ophthalmology. 2018
Tin Aung, Mineo Ozaki, Mei Chin Lee, Ursula Schlötzer-Schrehardt, Gudmar Thorleifsson, Takanori Mizoguchi, Robert P Igo Jr, Aravind Haripriya, Susan E Williams, Yury S Astakhov, et al. Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. Nature genetics. 2017. 49. 7. 993-1004
Itsuka Matsushita, Tatsuo Nagata, Takaaki Hayashi, Kenichi Kimoto, Toshiaki Kubota, Masahito Ohji, Shunji Kusaka, Hiroyuki Kondo. Foveal Hypoplasia in Patients with Stickler Syndrome. OPHTHALMOLOGY. 2017. 124. 6. 896-902
Francesca Pasutto, Matthias Zenkel, Ursula Hoja, Daniel Berner, Steffen Uebe, Fulvia Ferrazzi, Johannes Schoedel, Panah Liravi, Mineo Ozaki, Daniela Paoli, et al. Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1. NATURE COMMUNICATIONS. 2017. 8. 15466
Satoko Nakano, Sunao Sugita, Yasuhiro Tomaru, Ayumi Hono, Takako Nakamuro, Toshiaki Kubota, Hiroshi Takase, Manabu Mochizuki, Masayo Takahashi, Norio Shimizu. Establishment of Multiplex Solid-Phase Strip PCR Test for Detection of 24 Ocular Infectious Disease Pathogens. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2017. 58. 3. 1553-1559

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MISC (17)：

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Books (1)：

第13章視神経,第14章緑内障と低眼圧症候群(眼圧異常の病理)
Pathologie des Auges/眼病理学 2003

Works (4)：

眼科診療情報、基礎研究情報のデータベース構築とその応用に関する研究
2002 - 2003
眼内レンズ・屈折矯正手術に関する研究
2000 - 2002
落屑症候群の病因に関する共同研究
1994 - 1995
Cooperative Research on the Pathogenic of Exfoliation Syndrome
1994 - 1995

Education (4)：

- 1988 Kyushu University
- 1988 Kyushu University Medical Graduate Course Surgery
- 1982 Kyushu University School of Medicine
- 1982 Kyushu University Faculty of Medicine Medicine

Professional career (1)：

Docter(Medicine) (Kyushu University)

Work history (10)：

2004 - - 産業医科大学助教授
2004 - - Associate Professor, University of Occupational and
1992 - 1999 Kyushu University School of Medicine
1992 - 1999 Staff, Assistant Professor,Faculty of Medicine
1990 - 1992 Research fellow, Alexander von Humboldt Foundation

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Awards (1)：

2009/10 - 日本眼病理研究会学術奨励賞

Association Membership(s) (10)：

米国眼科アカデミー , 日本網膜硝子体学会 , 日本眼科手術学会 , 日本緑内障学会 , 日本眼科学会 , American Academy of Ophthalmology , The Vitreoretina Society of Japan , Japanese Society of Ophthalmic Surgeons , Japan Glaucoma Society , Japanese Ophthalmological Society

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