Research theme for competitive and other funds (31)：
2021 - 2027 加齢性難聴の克服に資する病態解明と次世代型医療の基盤技術の創出
2021 - 2024 Production of docile wild mice by the forward and reverse genetics approach
2019 - 2023 Identification of genetic factors act on heterogeneous pathology in microphthalmia using rat model
2018 - 2021 Measurement platform of nano-vibration in the cochlea for understanding the pathogenesis in deafness model mice
2016 - 2021 Redefinition of intractable inflammatory diseases based on mast cell activation syndrome
2016 - 2019 Development of locus- and/or neurotransmitter-specific cell depletion method in CNS and/or sensory organs
2015 - 2018 Function of scaffold proteins in the polarization of stereocilia on inner ear hair cells
2015 - 2018 Identification of functional genes in outer hair cells using an inducible depletion mouse model
2015 - 2018 Identification of the functional genomic polymorphisms affecting mouse progressive hearing loss
2015 - 2018 Identification of genetic risk factors and phenotypic rescue of deaf mutant mice based on technological innovations of the forward genetics approach
2015 - 2017 Exploring the function of an inner ear-specific myosin VI isoform
2013 - 2017 Generation and application of mouse models for neurodegenerative diseases by TRECK method
2012 - 2015 A novel mouse model for hearing impairment by selective ablation of OHCs in the inner ear
2011 - 2015 Comprehensive screening of genetic factors by using mouse models of age-related hearing loss in human for clinical application
2012 - 2014 Identification of the mechanism underlying the genetic modes of species-specific phenotypic differences
2011 - 2013 Analysis of the kinocilia influence in the cochlea outer hair cells
2009 - 2011 Bioimaging of mitochondrial dynamics and generation of model mice
2009 - 2011 Monitoring of social behavior associated with onset of hearing loss used model mice
2008 - 2010 Establishment and characterization of mouse models for hearing loss based on Molecular interaction
2008 - 2010 Development and characterization of genetic markers in goat : Application for QTL analysis of cashmere production used developed-genetic markers.
2006 - 2008 Identification of high recombination hotspots by transgenesis
2005 - 2008 CDH23 mutation in deaf patients and experimental animals
1998 - 2001 TOWARD TO POSITIONAL CLONING OF HUMAN POLYGENIC DISEASES USING MOUSE MODELS WITH SPECIAL REFERENCE TO ATOPIC DERMATITIS
1999 - 2000 聴覚障害モデルマウスを用いた内耳有毛細胞におけるキネシン様蛋白質の機能解析
1997 - 1998 聴覚障害モデルマウスを用いた内耳有毛細胞の分子機構の解明
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Papers (82)：
Xuehan Hou, Shumpei P Yasuda, Midori Yamaguchi, Sari Suzuki, Yuta Seki, Takafumi Ouchi, Ting Mao, Ornjira Prakhongcheep, Hiroshi Shitara, Yoshiaki Kikkawa. Impacts of an age-related hearing loss allele of cadherin 23 on severity of hearing loss in ICR and NOD/Shi mice. Biochemical and biophysical research communications. 2023. 674. 147-153
Hiroko Beppu, Tatsuya Fukuda, Naoya Otsubo, Tomoko Kawanishi, Toshie Ogawa, Yasutomo Abe, Mariko Endo, Tomohide Hanawa, Chise Sugita, Yoshiaki Kikkawa, et al. Serum chemokine CC-motif ligand 17 is a predictive marker of severe COVID-19 in haemodialysis patients: A retrospective observational study. Nephrology (Carlton, Vic.). 2023. 28. 4. 240-248
Sakiko Toyama, Tomoko Honda, Sadahiro Iwabuchi, Shinichi Hashimoto, Kenzaburo Yamaji, Yuko Tokunaga, Yusuke Matsumoto, Hideya Kawaji, Takashi Miyazaki, Yoshiaki Kikkawa, et al. Application of spatial transcriptomics analysis using the Visium system for the mouse nasal cavity after intranasal vaccination. Frontiers in immunology. 2023. 14. 1209945-1209945
Shumpei P. Yasuda, Yuki Miyasaka, Xuehan Hou, Yo Obara, Hiroshi Shitara, Yuta Seki, Kunie Matsuoka, Ai Takahashi, Eri Wakai, Hiroshi Hibino, et al. Two Loci Contribute to Age-Related Hearing Loss Resistance in the Japanese Wild-Derived Inbred MSM/Ms Mice. Biomedicines. 2022. 10. 9. 2221-2221
Ikuo Miura, Yoshiaki Kikkawa, Shumpei P. Yasuda, Akiko Shinogi, Daiki Usuda, Vivek Kumar, Joseph S. Takahashi, Masaru Tamura, Hiroshi Masuya, Shigeharu Wakana. Characterization of single nucleotide polymorphisms for a forward genetics approach using genetic crosses in C57BL/6 and BALB/c substrains of mice. Experimental Animals. 2022. 71. 2. 240-251
2018/05 - Experimental Animals The Most Excellent Paper of The Year on 2013
2014/05 - Experimental Animals The Most Excellent Paper of The Year on 2013
2007/06 - モロシヌス研究会 森脇和郎賞
2006/12 - 日本遺伝学会 Best Paper賞
2004/05 - 日本実験動物学会 奨励賞
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Association Membership(s) (9)：
THE JAPANESE SOCIETY FOR CATARACT RESEARCH
, JAPAN OTOLOGICAL SOCIETY
, 日本実験動物学会
, 日本遺伝学会
, 日本分子生物学会
, International Mammalian Genome Society
, Japanese Association for Laboratory Animal Science
, The Genetics Society of Japan
, The Molecular Biology Society of Japan
