Rchr
J-GLOBAL ID:200901023619301100   Update date: Mar. 30, 2024

Katsuhiko Shirahige

シラヒゲ カツヒコ | Katsuhiko Shirahige
Affiliation and department:
Job title: 教授
Research field  (4): Molecular biology ,  Genetics ,  Systems genomics ,  Genomics
Research keywords  (15): Genome Analysis ,  Chromosome function ,  Genome function ,  Chromosomal replication ,  Microbiome ,  Cancer ,  Transcriptional Regulation ,  Chromosome Structure ,  Chromosome Dynamics ,  Genetic disease ,  Cohesin ,  Chromosome ,  Genome Structure ,  分子生物学 ,  Molecular Biology
Research theme for competitive and other funds  (39):
  • 2022 - 2025 Elucidation of regulatory mechanisms of lipid metabolism in meibomian glands by changes in aging and indigenous bacterial flora
  • 2020 - 2025 Genomic modalities of development and differentiation and elucidation of disease mechanisms by their malfunction
  • 2020 - 2025 Genome modality: understanding physical properties of the genome
  • 2020 - 2025 Regulation of Enhanceosome by Cohesin
  • 2021 - 2024 Molecular mechanism of nuclear speckle disorders: NKAP-related syndrome as a model
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Papers (204):
  • Momoko Fukuda, Yuki Fujita, Yuko Hino, Mitsuyoshi Nakao, Katsuhiko Shirahige, Toshihide Yamashita. Inhibition of HDAC8 Reduces the Proliferation of Adult Neural Stem Cells in the Subventricular Zone. International Journal of Molecular Sciences. 2024. 25. 5. 2540-2540
  • Kristian Jeppsson, Biswajit Pradhan, Takashi Sutani, Toyonori Sakata, Miki Umeda Igarashi, Davide Giorgio Berta, Takaharu Kanno, Ryuichiro Nakato, Katsuhiko Shirahige, Eugene Kim, et al. Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils. Molecular cell. 2024
  • Miwako Kato Homma, Ryuichiro Nakato, Atsushi Niida, Masashige Bando, Katsunori Fujiki, Naoko Yokota, So Yamamoto, Takeshi Shibata, Motoki Takagi, Junko Yamaki, et al. Cell cycle-dependent gene networks for cell proliferation activated by nuclear CK2α complexes. Life science alliance. 2024. 7. 1
  • Ryuichiro Nakato, Toyonori Sakata, Jiankang Wang, Luis Augusto Eijy Nagai, Yuya Nagaoka, Gina Miku Oba, Masashige Bando, Katsuhiko Shirahige. Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors. Nature communications. 2023. 14. 1. 5647-5647
  • Huijuan Jia, Moe Miyoshi, Xuguang Li, Kyohei Furukawa, Lila Otani, Katsuhiko Shirahige, Fumihito Miura, Takashi Ito, Hisanori Kato. The Epigenetic Legacy of Maternal Protein Restriction: Renal Ptger1 DNA Methylation Changes in Hypertensive Rat Offspring. Nutrients. 2023. 15. 18. 3957-3957
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MISC (119):
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Books (2):
  • Genomic Approach for the Understanding of Dynamic Aspect of Chromosome Behavior
    Elsevier Life Sciences (CA) 2006
  • Genomic Approach for the Understanding of Dynamic Aspect of Chromosome Behavior
    Elsevier Life Sciences (CA) 2006
Lectures and oral presentations  (2):
  • Cohesin mediates transcriptional insulation by CCCTC-binding factor.
    (2008)
  • Cohesin mediates transcriptional insulation by CCCTC-binding factor.
    (2008)
Works (2):
  • 酵母のゲノム解析
    1999 -
  • Genomic Analyses of Brewing Yeasts
    1999 -
Education (3):
  • - 1994 Osaka University
  • - 1994 Osaka University Graduate School, Division of Medical Science
  • - 1988 The University of Tokyo College of Arts and Sciences Department of Basic Science
Professional career (1):
  • Doctor of Medical Science (Osaka University)
Work history (7):
  • 2018/04 - 現在 The University of Tokyo Institute for Quantitative Biosciences Professor
  • 2010/02 - 2018/03 The University of Tokyo Institute for Molecular and Cellular Biosciences Professor
  • 2007 - 2010/02 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Professor
  • 2004 - 2007 Tokyo Institute of Technology Gene Research Center Assistant Professor
  • 2001 - 2004 RIKEN GENOMIC SCIENCE CENTER Senior Researcher
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Awards (4):
  • 2010 - Ministry of Education, Culture, Sports, Science and Technology Prizes for Science and Technology (Research Category)
  • 2009 - Japan Society for the Promotion of Science Japan Society for the Promotion of Science Prize
  • 2008 - Nara Advanced Institute for Science and Technology NAIST Award for academic achievements
  • 2003 - 第一回日本分子生物学会三菱化学奨励賞
Association Membership(s) (2):
日本分子生物学会 ,  Molecular Biology Society of Japan
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