J-GLOBAL ID:200901023691926573   Update date: Aug. 29, 2020

Iinuma Hisae

イイヌマ ヒサエ | Iinuma Hisae
Affiliation and department:
Research field  (3): Tumor diagnostics and therapeutics ,  Medical biochemistry ,  Digestive surgery
Research keywords  (7): Immunotherapy ,  Pathological Medical Chemistry ,  Immunology ,  Gastroenterological Surgery ,  Cancer ,  Genetic diagnosis ,  Biomarker
Papers (97):
  • Keiji Matsuda, Yojiro Hashiguchi, Mitsuo Tsukamoto, Kohei Ohno, Yuka Okada, Takahiro Yagi, Yoshihisa Fukushima, Atsushi Horiuchi, Ryu Shimada, Tsuyoshi Ozawa, Tamuro Hayama, Takeshi Tsuchiya, Junko Tamura, Hisae Iinuma, Keijiro Nozawa, Yuko Sasajima, Fukuo Kondo. A case report of successful management of fulminant Clostridium difficile colitis post-ileostomy reversal with administration of vancomycin through a transverse colostomy. Surgical case reports. 2019. 5. 1. 181-181
  • Tamuro Hayama, Yojiro Hashiguchi, Koichi Okamoto, Yuka Okada, Kohei Ono, Ryu Shimada, Tsuyoshi Ozawa, Tetsutaka Toyoda, Takeshi Tsuchiya, Hisae Iinuma, Keijiro Nozawa, Keiji Matsuda. G12V and G12C mutations in the gene KRAS are associated with a poorer prognosis in primary colorectal cancer. International journal of colorectal disease. 2019. 34. 8. 1491-1496
  • Soeda N, Iinuma H, Suzuki Y, Tsukahara D, Midorikawa H, Igarashi Y, Kumata Y, Horikawa M, Kiyokawa T, Fukagawa T, Fukushima R. Plasma exosome-encapsulated microRNA-21 and microRNA-92a are promising biomarkers for the prediction of peritoneal recurrence in patients with gastric cancer. Oncol Lett. 2019. 18. 5. 4467-4480
  • Iinuma H. Genomic Analysis and Immunotherapy by Liquid Biopsy. Gan To Kagaku Ryoho. 2019. 46. 9. 1361-1366
  • Yagi T, Iinuma H, Hayama T, Matsuda K, Nozawa K, Tsukamoto M, Shimada R, Akahane T, Tsuchiya T, Ozawa T, Hashiguchi Y. Plasma exosomal microRNA-125b as a monitoring biomarker of resistance to mFOLFOX6-based chemotherapy in advanced and recurrent colorectal cancer patients. Mol Clin Oncol. 2019. 11. 4. 416-424
MISC (5):
Lectures and oral presentations  (8):
  • Clinical Significance of Circulating Exosomal microRNA as a Biomarker in Each Tumor Stage of Colorectal Cancer.
  • Clinical impact of plasma exosomal microRNA-21 as a biomarker in human colorectal cancer patients
    (第73回日本癌会学術集会 2014)
  • Treatment strategy for lower rectal cancer
    (第73回日本癌会学術集会 2014)
  • Identification of the bona-fide biomarkers for circulating exosomal microRNA in liver and colorectalc cancer patients
    (第73回日本癌会学術集会 2014)
  • Molecular characteristics of CTC and usefulness as biomarker in ESCC patients treated with peptide vaccines
    (第73回日本癌会学術集会 2014)
Works (4):
  • Assessment of Th1/Th2 balance for monitoring of BRM immunotherapy
    2000 - 2006
  • Dendritic cell immunotherapy for patients with neuroblastoma
    2001 - 2004
  • Molecular detection of micrometastasis of tumor cells
    2001 - 2004
  • Antitumor effect of CDDP-encapsulated PEG-modified liposome on carcinomatous Peritonitis
    1998 - 2000
Professional career (1):
  • PH.D. (Teikyo University)
Work history (5):
  • 2018/04 - 現在 Teikyo University
  • 2003/06 - 現在 Teikyo University School of Medicine
  • 2015/04 - 2018/03 Teikyo University
  • 1980/04 - 2003/05 Teikyo University
  • 1978 - 1980 National Institute of Health
Association Membership(s) (3):
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