Rchr
J-GLOBAL ID:200901023859645613   Update date: Jun. 25, 2024

Shimada Masayuki

シマダ マサユキ | Shimada Masayuki
Affiliation and department:
Research theme for competitive and other funds  (23):
  • 2019 - 2021 卵巣間質の間葉系幹細胞に着眼した卵巣加齢化メカニズム解明と予防・根治法開発
  • 2018 - 2019 1卵胞を構成する体細胞を用いた卵子加齢変化の診断法の開発、2卵子の質の低下による高齢不妊の治療法の開発、3卵巣組織凍結法の改良、有効性・安全性の検証
  • 2017 - 2018 1卵胞を構成する体細胞を用いた卵子加齢変化の診断法の開発、2卵子の質の低下による高齢不妊の治療法の開発、3卵巣組織凍結法の改良、有効性・安全性の検証
  • 2017 - 2018 モデルマウス作製による受精障害予防と治療法開発への挑戦
  • 2016 - 2018 The epigenetic regulation of follicular development by the expression of non-coding RNA
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Papers (129):
  • Umehara, Takashi, Winstanley, Yasmyn E., Andreas, Eryk, Morimoto, Atsushi, Williams, Elisha J., Smith, Kirsten M., Carroll, John, Febbraio, Mark A., Shimada, Masayuki, Russell, Darryl L., et al. Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary. SCIENCE ADVANCES. 2022. 8. 24
  • Ma, Dongxue, Marey, Mohamed Ali, Shimada, Masayuki, Miyamoto, Akio. Toll-like Receptor 2 is Involved in Calcium Influx and Acrosome Reaction to Facilitate Sperm Penetration to Oocytes During in vitro Fertilization in Cattle. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022. 10
  • Akthar, Ihshan, Marey, Mohamed A., Kim, Yejin, Shimada, Masayuki, Suarez, Susan S., Miyamoto, Akio. Sperm interaction with the uterine innate immune system: toll-like receptor 2 (TLR2) is a main sensor in cattle. REPRODUCTION FERTILITY AND DEVELOPMENT. 2022. 34. 2. 139-148
  • Kawai, Tomoko, Richards, JoAnne S., Shimada, Masayuki. Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development. COMMUNICATIONS BIOLOGY. 2021. 4. 1
  • Nakanishi, Tomoya, Tanaka, Risa, Tonai, Shingo, Lee, Joo Yeon, Yamaoka, Manami, Kawai, Tomoko, Okamoto, Asako, Shimada, Masayuki, Yamashita, Yasuhisa. LH Induces De Novo Cholesterol Biosynthesis via SREBP Activation in Granulosa Cells During Ovulation in Female Mice. ENDOCRINOLOGY. 2021. 162. 11
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Patents (8):
  • ブタ精子凍結希釈液用添加剤及びブタ精子の凍結保存方法
  • 精子用希釈液、及び、これを用いた人工授精方法
  • 受胎率および産子数向上凍結精子およびその製法
  • ヒト凍結精子用希釈液、ヒト凍結精子の希釈方法、及び、ヒトの体外受精用精液又は人工授精用精液の調整方法
  • ヒトの体外受精用精液又は人工授精用精液の調整方法
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Lectures and oral presentations  (55):
  • Metabolic Decline of Ovarian Stromal Cells with Aging: Inducing Ovarian Fibrosis and Inhibiting Follicular Development
    (KSRM-JSRM joint session, The 68th Annual Meeting of Japan Society for Reproductive Medicine 2023)
  • 卵子の質に及ぼす酸化ストレスの影響
    (第68回日本生殖医学会学術講演会・総会 2023)
  • ミトコンドリア機能低下が引き起こす卵巣老化,その老化防止と根治法の開発
    (第23回日本抗加齢医学会総会 2023)
  • 間葉系幹(間質)細胞に着眼した新たな人工授精/体外受精法開発の試み
    (第157回 関東生殖医学会 2023)
  • 精巣機能のアンチエイジング
    (第14 回泌尿器抗加齢医学研究会 2023)
more...
Professional career (1):
  • Doctor of Philosophy (Yamaguchi University)
Work history (2):
  • 2017/04/01 - 2019/03/31 Hiroshima University Graduate School of Biosphere Science Professor
  • 2007/04/01 - 2017/03/31 Hiroshima University Graduate School of Biosphere Science Associate Professor
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