Hirota Kazuyoshi

2017 - 2021 Investigation of mechanism of pathogenesis of postoperative and sepsis-associated delirium and cognitive dysfunction and development of the prophylaxis.

2015 - 2018 Role of orexinergic neurons in sepsis

2014 - 2018 Searching way of more gentle emergence from general anesthesia-An approach from anesthesiology and sleep to ERAS-

2013 - 2015 麻酔後睡眠障害の治療戦略:睡眠ホメオスタシス調節の視点からのアプローチ

2012 - 2015 Study on analgesic effects of neuropeptide S

2011 - 2013 A study on the treatment of post anesthesia and surgical sleep disturbance

2010 - 2012 Sleep and general anesthesia : maintaining patient safety and improving the QOL during perioperative period

2009 - 2012 Stud for the mechanism of aging and anesthesia-related sleep disorder and its treatment.

2008 - 2010 Study on a mechanism of emergence from general anesthesia-apply of the ascending arousal system for smooth recovery from general anesthesia

2007 - 2009 生理活性物質ウロテンシンIIの全身麻酔および睡眠への関与

2009 - 加齢および麻酔と睡眠障害

2007 - 2008 The effects of massage for symptom relief

2006 - 2008 The relationship between sleep and anesthesia as a clueto elucidate the mechanism of general anesthesia

2005 - 2007 A study of post anesthetic and operative sleep disturbance. An approach to the mechanism and treatment on the disturbance.

2005 - 2007 Brain orexinergic-noradrenergic neurons and mechanism of general anesthesia

2002 - 2004 Unitary mechanism of general anesthesia using brain noradrenergic neuronal network.

2003 - 2003 全身麻酔中の低体温予防の研究-中枢性ノルエピネフリン作動性神経活性は関与するか

2001 - 2002 新生理活性物質ノシセプチンの内因性気道拡張因子としての役割の検討-喘息治療薬としての可能性

2001 - 2002 A study on the mechanism of General Anesthesia-inuduced sleep-relation to endogenous sleep related substances

2002 - 麻酔前投薬としてのH2受容体拮抗薬の有効性に関する研究

1997 - 2000 Contribution of L-type Voltage Sensitive Ca^<2+> Channels to Mechanism of General Anesthesia

1996 - 1996 向精神薬ドロペリドールの気管支拡張作用-超細臣ファイバースコープによる直視的判定法-

1994 - 1994 喘息発作状態に対するNMDA受容体遮断薬の治療効果