Rchr
J-GLOBAL ID:200901024717858438   Update date: May. 27, 2020

Takayama Hiromitsu

タカヤマ ヒロミツ | Takayama Hiromitsu
Affiliation and department:
Job title: Full Professor
Homepage URL  (2): http://www.p.chiba-u.jp/lab/skb/index.htmlhttp://www.p.chiba-u.jp/lab/skb/index_e.html
Research field  (3): Pharmaceuticals - chemistry and drug development ,  Environmental and pharmaceutical development resources ,  Pharmaceuticals - chemistry and drug development
Research keywords  (4): Alkaloid ,  Medicinal Chemistry ,  Organic Chemistry ,  Natural Product Chemistry
Papers (346):
  • Takayama, H. Total Syntheses of Lycopodium and Monoterpenoid Indole Alkaloids Based on Biosynthesis-Inspired Strategies. Chem. Pharm. Bull. 2020. 68. 2. 103-116
  • Kawabata, H, Hirama, T, Yanagisawa, T, Sato, K, Kogure, N, Kitajima, M, Takayama, H. Asymmetric Total Synthesis of Biphenylquinolizidine Alkaloids 4”-O-Demethyllythridine and 14-epi-4”-O-Demethyllythridine. Org. Lett. 2019. 21. 19. 7982-7986
  • Saito, A, Kogure, N, Kitajima, M, Takayama, H. Total Synthesis of (-)-14-Hydroxygelsenicine and Six Biogenetically Related Gelsemium Alkaloids. Org. Lett. 2019. 21. 17. 7134-7137
  • Kitajima, M, Yamaguchi, Y, Yanagisawa,T, Kogure, N, Ogata, J, Kikura-Hanajiri, R, Takayama, H. Biphenyl quinolizidine lactone alkaloids from "sinicuichi" (Heimia salicifolia). Tetrahedron. 2019. 75. 27. 3733-3739
  • Sato, K, Kogure, N, Kitajima, M, Takayama, H. Total Syntheses of Pleiocarpamine, Normavacurine, and C-Mavacurine. Org. Lett. 2019. 21. 9. 3342-3345
more...
MISC (7):
  • Nakabayashi Ryo, Yonekura-Sakakibara Keiko, Matsuda Fumio, Tohge Takayuki, Kitajima Mariko, Takayama Hiromitsu, Yamazaki Mami, Saito Kazuki. The effect of double over-expressions of two MYB genes on gene expression and flavonoid accumulation in Arabidopsis. Plant and Cell Physiology Supplement. 2010. 2010. 0. 868-868
  • 浅野 孝, 須藤 浩, 北島 満里子, 高山 廣光, 相見 則郎, 山崎 真巳, 斉藤 和季. リュウキュウイナモリ毛状根のエリシター等によるインドールアルカロイド生産制御. 日本生薬学会年会講演要旨集. 2004. 51回. 40-40
  • 浅野 孝, 山崎 泰代, 浦野 晶子, 須藤 浩, 北島 満里子, 高山 廣光, 山崎 真巳, 相見 則郎, 斉藤 和季. サツマイナモリ属植物及びその組織培養物におけるアルカロイドプロファイリング. 日本生薬学会年会講演要旨集. 2003. 50回. 214-214
  • 北島 満里子, 丹羽 美苗, 柳沢 知恵子, 高山 廣光, 斉藤 和季, 山崎 真巳, 須藤 浩, 相見 則郎. アカネ科Ophiorrhiza pumila毛状根培養液中の成分探索. 日本薬学会年会要旨集. 2002. 122年会. 2. 130-130
  • 北島 満里子, 柳沢 知恵子, 山形 恭子, 高山 廣光, 山崎 真巳, 斉藤 和季, 相見 則郎. アカネ科チャボイナモリOphiorrhiza pumilaの毛状根代謝産物の化学的研究. 日本薬学会年会要旨集. 1999. 119年会. 2. 129-129
more...
Patents (5):
  • Opioid analgesic
  • Indole Alkaloid Derivatives Having Opioid Receptor Agonistic Effect and Therapeutic Compositions and Methods Relating To Same.
  • Compound having activity of blocking NMDA receptor channel, and pharmaceutical agent using the same.
  • Indole alkaloid derivatives having opioid receptor antagonistic effect, and therapeutic compositions and methods relating to same.
  • Process for Producing Corosolic Acid.
Books (2):
  • The Alkaloids: Chemistry and Biology Vol.82
    Academic Press 2019
  • Science of Alkaloids
    2017
Works (1):
  • Isolation and Total Synthesis of Bioactive Alkaloids
Professional career (1):
  • PhD
Work history (5):
  • 2004/04 - 2020/03 Chiba University
  • 1994/10 - 2004/03 Chiba University Associate Professor
  • 1986/07 - 1994/09 Chiba University Assistant Professor
  • 1984/04 - 1986/06 Toyama Medical and Pharmaceutical University Assistant Professor
  • 1982/04 - 1984/03 Hannover University Posdoc. (Alexander von Humboldt Foundation)
Committee career (4):
  • 2018/04 - 2019/03 The Pharmaceutical Society of Japan Controller
  • 2017/04 - 2019/02 Division of Medicinal Chemistry, The Pharmaceutical Society of Japan Division Head
  • 2014/04 - 2016/03 Chiba University, Graduate School of Pharmaceutical Sciences Dean
  • 2014/04 - 2016/03 The Pharmaceutical Society of Japan Director
Awards (4):
  • 2018/03 - The Pharmaceutical Society of Japan The Pharmaceutical Society of Japan Award
  • 2015/09 - The Japanese Society of Pharmacognosy The Japanese Society of Pharmacognosy Award
  • 2004/03 - The Pharmaceutical Society of Japan The Pharmaceutical Society of Japan Award for for Divisional Scientific Promotion
  • 2000/03 - The Pharmaceutical Society of Japan The Sato Memorial Domestic Award
Association Membership(s) (6):
German Chemical Society ,  American Chemical Society ,  THE CHEMICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF PHARMACOGNOSY ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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