Rchr
J-GLOBAL ID:200901024717858438   Update date: Oct. 30, 2020

Takayama Hiromitsu

タカヤマ ヒロミツ | Takayama Hiromitsu
Affiliation and department:
Job title: Full Professor
Homepage URL  (2): http://www.p.chiba-u.jp/lab/skb/index.htmlhttp://www.p.chiba-u.jp/lab/skb/index_e.html
Research field  (3): Pharmaceuticals - chemistry and drug development ,  Environmental and pharmaceutical development resources ,  Pharmaceuticals - chemistry and drug development
Research keywords  (7): Alkaloid ,  Medicinal Chemistry ,  Organic Chemistry ,  Natural Product Chemistry ,  医薬化学 ,  有機化学 ,  天然物化学
Research theme for competitive and other funds  (19):
  • 2017 - 2020 アルカロイド由来の新規有機不斉触媒と特定配列オリゴヌクレオチド認識分子の創製
  • 2016 - 2019 植物アルカロイドの探索と合成研究を基盤とした、疼痛および脳機能改善薬の創成
  • 2014 - 2017 天然オピオイド類の体内動態解明を目的としたSPECT用プローブの創製
  • 2013 - 2016 薬用資源植物を素材とした記憶と痛みを制御する天然分子の探索と創薬研究への展開
  • 2013 - 2015 ピロリジジンアルカロイド類分析用標準試薬の作製と分析法の検討
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Papers (376):
MISC (28):
  • Yuko Terada, Syunji Horie, Hiromitsu Takayama, Tatsuo Watanabe. New class TRPM8 antagonist, voacangine is the first natural competitive antagonist for menthol receptor, TRPM8. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2013. 245
  • Nakabayashi Ryo, Yonekura-Sakakibara Keiko, Matsuda Fumio, Tohge Takayuki, Kitajima Mariko, Takayama Hiromitsu, Yamazaki Mami, Saito Kazuki. The effect of double over-expressions of two MYB genes on gene expression and flavonoid accumulation in Arabidopsis. Plant and Cell Physiology Supplement. 2010. 2010. 0. 868-868
  • Yuqiu Wu, Marliko Kitajima, Noriyuki Kogure, Rongping Zhang, Hiromitsu Takayama. Two novel indole alkaloids, Kopsiyunnanines A and B, from a Yunnan Kopsia (vol 49, pg 5935, 2008). TETRAHEDRON LETTERS. 2008. 49. 46. 6596-6596
  • Euis H. Hakim, Sjamsul A. Achmad, Lia D. Juliawaty, Lukman Makmur, Yana M. Syah, Norio Aimi, Mariko Kitajima, Hiromitsu Takayama, Emilio L. Ghisalberti. Prenylated flavonoids and related compounds of the Indonesian Artocarpus (Moraceae) (vol 60, pg 161, 2006). JOURNAL OF NATURAL MEDICINES. 2007. 61. 2. 229-229
  • Mariko Kitajima, Tomonori Nakamura, Noriyuki Kogure, Mio Ogawa, Yuka Mitsuno, Kageyoshi Ono, Shingo Yano, Norio Aimi, Hiromitsu Takayama. Isolation of gelsedine-type indole alkaloids from Gelsemium elegans and evaluation of the cytotoxic activity of Gelsemium alkaloids for A431 epidermoid carcinoma cells (vol 69, pg 715, 2006). JOURNAL OF NATURAL PRODUCTS. 2007. 70. 1. 142-142
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Patents (19):
  • Opioid analgesic
  • Indole Alkaloid Derivatives Having Opioid Receptor Agonistic Effect and Therapeutic Compositions and Methods Relating To Same.
  • Compound having activity of blocking NMDA receptor channel, and pharmaceutical agent using the same.
  • Compound having activity of blocking NMDA receptor channel, and pharmaceutical agent using the same.
  • Indole alkaloid derivatives having opioid receptor agonistic effect, and therapeutic compositions and methods relating to same
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Books (27):
  • The Alkaloids: Chemistry and Biology Vol.82
    Academic Press 2019
  • 天然物の化学II
    東京化学同人 2018
  • トキシコロジー 第3版
    朝倉書店 2018
  • Science of Alkaloids
    2017
  • スタンダード薬学シリーズII 3 化学系薬学 III. 自然が生み出す薬物
    東京化学同人 2016
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Works (8):
  • 熱帯産薬用資源植物の化学的研究
    1996 - 2006
  • 抗ウイルス剤の開発研究
    1995 - 1999
  • アルカロイドの不斉全合成
    高山 廣光
  • 天然物由来の抗腫瘍剤の開発研究
  • 違法ドラッグの乱用防止策に関する研究
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Professional career (1):
  • PhD
Work history (6):
  • 2020/04 - 現在 千葉大学
  • 2004/04 - 2020/03 Chiba University Graduate School of Pharmaceutical Sciences
  • 1994/10 - 2004/03 Chiba University Faculty of Pharmaceutical Sciences Associate Professor
  • 1986/07 - 1994/09 Chiba University Faculty of Pharmaceutical Sciences Assistant Professor
  • 1984/04 - 1986/06 Toyama Medical and Pharmaceutical University Faculty of Pharmaceutical Sciences Assistant Professor
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Committee career (9):
  • 2019/04 - 2021/03 日本薬学会 副会頭
  • 2018/04 - 2019/03 The Pharmaceutical Society of Japan Controller
  • 2018/04 - 2019/03 日本薬学会 監事
  • 2017/04 - 2019/03 日本薬学会 医薬化学部会長
  • 2017/04 - 2019/02 Division of Medicinal Chemistry, The Pharmaceutical Society of Japan Division Head
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Awards (12):
  • 2018/03 - The Pharmaceutical Society of Japan The Pharmaceutical Society of Japan Award
  • 2018/03 - 日本薬学会 学会賞
  • 2015/09 - The Japanese Society of Pharmacognosy The Japanese Society of Pharmacognosy Award
  • 2015/09 - 日本生薬学会賞
  • 2014/11 - 日本薬学会医薬化学部会 メディシナルケミストリーシンポジウム優秀賞
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Association Membership(s) (9):
German Chemical Society ,  American Chemical Society ,  THE CHEMICAL SOCIETY OF JAPAN ,  国際複素環学会 ,  THE JAPANESE SOCIETY OF PHARMACOGNOSY ,  ドイツ化学会 ,  アメリカ化学会 (American chemical Society) ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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