Rchr
J-GLOBAL ID:200901025298643155   Update date: Feb. 01, 2024

Hara Hiroshi

ハラ ヒロシ | Hara Hiroshi
Affiliation and department:
Job title: Professor
Research field  (3): Clinical pharmacy ,  Physiology ,  Food sciences
Research keywords  (9): 食品ペプチドの生理作用 ,  Gut hormones ,  Ether-type phospholipids ,  Flavonoid absorption ,  Mineral absorption ,  Nondigestible saccharides ,  消化管生理学 ,  栄養生化学 ,  Nutritional Biochemistry Gastrointestinal Physiology
Research theme for competitive and other funds  (19):
  • 2018 - 2019 食後の消化管ホルモン分泌応答や栄養吸収の時空間的解析とその栄養学的意義
  • 2017 - 2019 Study on physiological effects of isomalto-megalo-saccharides
  • 2016 - 2017 Study on sensing mechanism of low-digestible saccharides in nutrient-sensing enteroendocrine cells
  • 2014 - 2016 Study on enteroendocrine, nervous and reproductive systems related to diet for preventing metabolic diseases.
  • 2014 - 2015 アンカー型イソマルトメガロ糖の生産技術確立とその分子特性に基づ く食品素材の開発
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Papers (299):
  • Weeranuch Lang, Takayoshi Tagami, Yuya Kumagai, Seiya Tanaka, Hye-Jin Kang, Masayuki Okuyama, Wataru Saburi, Haruhide Mori, Tohru Hira, Chaehun Lee, et al. Tunable structure of chimeric isomaltomegalosaccharides with double α-(1 → 4)-glucosyl chains enhances the solubility of water-insoluble bioactive compounds. Carbohydrate Polymers. 2023. 319. 121185-121185
  • Seiya Tanaka, Aphichat Trakooncharoenvit, Miyu Nishikawa, Shinichi Ikushiro, Hiroshi Hara. Heteroconjugates of quercetin with 4′-O-sulfate selectively accumulate in rat plasma due to limited urinary excretion. Food & Function. 2022. 13. 3. 1459-1471
  • Jukkrapong Pinyo, Hiroshi Hara, Tohru Hira. Diet-induced obesity enhances postprandial glucagon-like peptide-1 secretion in Wistar rats, but not in diabetic Goto-Kakizaki rats. The British journal of nutrition. 2021. 126. 4. 518-530
  • Tohru Hira, Aphichat Trakooncharoenvit, Hayate Taguchi, Hiroshi Hara. Improvement of Glucose Tolerance by Food Factors Having Glucagon-Like Peptide-1 Releasing Activity. International journal of molecular sciences. 2021. 22. 12
  • Aphichat Trakooncharoenvit, Hiroshi Hara, Tohru Hira. Combination of α-Glycosyl-Isoquercitrin and Soybean Fiber Promotes Quercetin Bioavailability and Glucagon-like Peptide-1 Secretion and Improves Glucose Homeostasis in Rats Fed a High-Fat High-Sucrose Diet. Journal of agricultural and food chemistry. 2021. 69. 21. 5907-5916
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MISC (146):
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Patents (58):
Books (24):
  • Effects of non-digestible saccharides on the enteroendocrine system
    2019
  • Physiological Function of Plasmalogens
    2018
  • 食品成分による消化管機能の調節「消化管から見た健康・栄養」
    建帛社 2018
  • Absorption, Metabolism, and Mechanisms of Action of Functional Food Compounds
    2018
  • 難消化性オリゴ糖によるフラボノイド生理作用の増強「食品因子による栄養機能制御」
    建帛社 2015
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Lectures and oral presentations  (110):
  • Plasmalogens, phospholipids associated with arteriosclerosis and dementia
    (2019)
  • Various physiological effects of sugar
    (2019)
  • 機能性食品としての糖
    (日本農芸化学会北海道支部大会 特別講演、札幌市 2018)
  • 消化管上皮バリアを維持する 未病改善のキーファクター
    (第25回 日本未病システム学会学術総会 教育講演、一ツ橋講堂(東京) 2018)
  • フラボノイドの生体利用性を高める機能性糖
    (OPUセミナー“私たちの食生活と食品の機能・加工”招待講演 大阪府立大学I-siteなんば (大阪市) 2018)
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Works (2):
  • Physiological effects of short-chain fatty acids produced from prebiotics in the colon.
    2006 -
  • Oligosaccharides, a functional food to promote calcium absorption and prevent osteoporosis.
    2004 -
Education (2):
  • 1976 - 1978 名古屋大学大学院 農学研究科 農芸化学専攻
  • 1972 - 1976 Tokyo University of Agriculture and Technology Faculty of Agriculture
Professional career (1):
  • PhD (Hokkaido University)
Committee career (22):
  • 2019 - 現在 Japan Polyphenol Society Administrator
  • 2018 - 現在 The Japanese Society for Food Analysis Administrator
  • 2015 - 現在 日本未病学会(旧未病システム学会) 評議員
  • 2007 - 現在 日本食物繊維学会 理事
  • 2007 - 現在 油脂・コレステロール研究会 理事
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Awards (6):
  • 2011/05 - 日本栄養・食糧学会 学会賞 「消化管の中で生理作用を発揮する食品成分に関する研究」
  • 2010/11 - 日本食物繊維学会 学会賞 「難消化性食品成分による消化吸収促進機構の解明と、新たなルミナコイド成分の提案」
  • 2008 - 6th IFS (International Fructan Symposium) AWARD for the Best Paster Presentation
  • 2004 - 9th John M. Kinney International Award for general Nutrition "Ingestion of water-soluble soybean fiber improves gastrectomy-induced calcium malabsorption and osteopenia in rats."
  • 2002 - 日本消化吸収学会 学会賞
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Association Membership(s) (15):
Japan Polyphenol Society ,  The Japanease Society for Food Analysis ,  Japan Mibyou Association ,  Japanese Society for Amino Acid Sciences ,  The Japanese Society for Food Science and Technology ,  Japanese Association of Dietary Fiber Research ,  The Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA) ,  Japanese Society of Nutrition and Food Science ,  The Japanese Biochemical Society ,  The Japanese Society of Applied Glycoscience ,  The Japanese Society of Nutrion and Dietetics ,  The Japanese Society of Digestion and Absorption ,  Japanese Association for Animal Cell Technology ,  Hindgut Club Japan ,  油脂・コレステロール研究会
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