Research field (2):
Analytical chemistry
, Biochemistry
Research keywords (9):
Fragmentation
, Hydrogen radical
, Protein Chemistry
, Matrix-assisted laser desorption/ionization
, Ionization
, 気相イオン化学
, 質量分析
, Gas-phase ion chemistry
, Mass Spectrometry
Research theme for competitive and other funds (8):
2019 - 2022 水素ラジカルによるジスルフィド結合含有タンパク質の新規分析法
2015 - 2017 水素ラジカルに対する有機材料の耐性・劣化の分子機構
2008 - 2017 翻訳後修飾プロテオミクス医療研究拠点の形成
2011 - 2013 大気中での水素ラジカル関与の特異な反応の基礎研究
2008 - 2010 水素ラジカルによる特異な分解反応の基礎研究とタンパク質化学への応用
2006 - 2007 水素ラジカルによる特異な分解反応の制御に関する基礎研究
2001 - 2002 Analysis of transient expression of estrogen receptor in the newborn rat brain
1985 - Ioniozation methods for mass spectrometry
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Papers (152):
Mitsuo Takayama, Masaaki Ubukata, Kenji Nagatomo, Jun Tamura, Azusa Kubota. Quantum Chemical Analysis of Molecular and Fragment Ions Produced by Field Ionization of Methyl Stearate. J. Am. Soc. Mass Spectrom. 2023. 34. 2731-2738
Mitsuo Takayama. Transient conformations leading to peptide fragment ion [c + 2H]+ via intramolecular hydrogen bonding using MALDI in-source decay mass spectrometry of serine-, threonine-, and/or cysteine-containing peptides. Molecules. 2023. 28. 7700. 1-14
Shiho Fujishima, Kanako Sekimoto, Mitsuo Takayama. Identification of Negative Ion at m/z 20 Produced by Atmospheric Pressure Corona Discharge Ionization under Ambient Air. Mass Spectrometry (Tokyo). 2023
Yuka Fujito, Yoshihiro Izumi, Kohta Nakatani, Masatomo Takahashi, Yoshihiro Hayakawa, Mitsuo Takayama, Takeshi Bamba. Understanding the Mechanism of CO2-Assisted Electrospray Ionization for Parameter Optimization in Supercritical Fluid Chromatography Mass Spectrometry. Analytica Chimica Acta. 2023. 1246. 340863
M.TakayamaM, UbukataK.OhshimoK.NagatomoF.Misaizu. Identification of complementary McLafferty rearrangement ions at m/z 222 and 224 of methylstearate using high-resolution electron ionization time-of-flight mass spectrometer. International Journal of Mass Spectrometry. 2023. 484. 116978
Complete classification, separation, and accurate analysis of fragment ions produced by electron ionization of methyl stearate using a high-performance mass spectrometer GC/MS JMS-T2000GC and quantum chemical calculations. JEOL NEWS. 2024. 59. 1. 24-30
Mitsuo Takayama, Masaaki Ubukata. Complete calassification, separation, ans accurate analysis of fragment ions produced by electron ionization of mathyl stearate using a high-performance mass spectrometer GC/MS JMS-T2000GC and quantum chemical calculations. JEOL NEWS. 2024. 56. 1. 12-18
坂倉幹始, 関本奏子, 比毛浩, 高山光男. New ion source for Ambient ionization using Argon gas. 質量分析総合討論会講演要旨集. 2020. 68th
Quantitative quantum chemical analysis of linear and branched alkyl chain fragment ions produced by field ionization of methyl stearate, heptane, and methyl heptanes
(The 72th Annual Conference on Mass Spectrometry 2024)
Production and Structure of Dipole-Bound Complex Anion (H2∙H2O)-
(The 26th Annual Conference on Japan Society of Theoretical Chemistry 2024)
Field ionization fragmentation analysis of methyl stearate using high-accurate time-of-flight mass spectrometer, based on the concepts of low-internal energy mass spectrometry
(The 71st Annual Conference on Mass Spectrometry 2023)
Intramolecular charge-splitting in complementary McLafferty rearrangement reaction based on high-accurate EIMS and density functional theory
(The 71st Annual Conference on Mass Spectrometry 2023)
2020/04 - 2021/03 Yokohama City University International College of Arts and Sciences, Department of Materials Science Graduate School of Nanobioscience Department of Materials System Science
2020/04 - 2021/03 Yokohama City University Professor
2019/04 - 2021/03 Yokohama City University Faculty of Science Professor
2005/04 - 2021/03 Yokohama City University Professor
2011/04 - 2019/03 Yokohama City University
2016/04 - 2018/03 Yokohama City University Kihara Institute for Biological Research Director of Kihara Institute for Biological Research
2014/04 - 2015/03 Yokohama City University Kihara Institute for Biological Research Director
2008/03 - 2010/03 Yokohama City University Dean, Faculty Research Program
2006/04 - 2008/03 Yokohama City University Director
2004/11 - 2005/03 Yokohama City University Professor
2001/05 - 2004/10 Yokohama City University Associate Professor
2001/04 - Toho University Faculty of Pharmaceutical Sciences
1980/04 - Toho University Faculty of Pharmaceutical Sciences
1977/10 - 1980/03 Toho University Pharmaceutical Science Technical Stuff
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Committee career (11):
2023/01 - 現在 Advisory Board Member in Journal of Mass Spectrometry (Wiley Analytical Science)
2017/05 - 2021/06 日本質量分析学会 会長
2016/06 - 2018/06 木原記念横浜生命科学振興財団 評議員
2012 - 2018 Mass Spectrometry (Tokyo) Editroial Board
2006 - 2007 International Union of Pure and Applied Chemistry Reviewer
2000 - 2006 Journal of Mass Spectrometry Editroial Board
2000 - 2005 Proteomics Editroial Board
1997 - 2000 The American Society for Mass Spectrometry Editroial Board
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Awards (4):
2024/06 - The Mass Spectrometry Society of Japan Research paper award Identification of negative ion at m/z20 produced by atmospheric pressure corona discharge ionization under ambient air
2016/05 - Mass Spectrometry Society of Japan MSSJ Award for Distinguished Contribution in MS Model Construction for MALDI In-Source Decay Mechanism
2002/05 - Mass Spectrometry Society of Japan Journal Award
1994/05 - Mass Spectrometry Society of Japan MSSJ Research Award Ion Formation Mechanism by Fast Atom Bombardment