J-GLOBAL ID:200901025817184333   Update date: Jun. 07, 2020

Kokubo Tetsuro

コクボ テツロウ | Kokubo Tetsuro
Affiliation and department:
Homepage URL  (1): http://www.tsurumi.yokohama-cu.ac.jp/mcbl/index2.html
Research field  (1): Molecular biology
Research keywords  (8): RNA binding ptotein ,  budding yeast ,  transcriptional regulation ,  MRI ,  imaging ,  TAF ,  TFIID ,  general transcription factor
Research theme for competitive and other funds  (1):
  • Biochemical and genetic analysis of the function of TFIID subunits
Papers (66):
  • Wei Y, Resetca D, Li Z, Johansson-Åkhe I, Ahlner A, Helander S, Wallenhammar A, Morad V, Raught B, Wallner B, Kokubo T, Tong Y, Penn LZ, Sunnerhagen M. Multiple direct interactions of TBP with the MYC oncoprotein. Nat Struct Mol Biol. 2019. 26. 11. 1035-1043
  • Kasahara K, Takahata S, Kokubo T. Transcriptional activation is weakened when Taf1p N-terminal domain 1 is substituted with its Drosophila counterpart in yeast TFIID. Genes & Genetic Systems. 2019. 94. 1. 51-59
  • Kiyoshi Watanabe, Tetsuro Kokubo. SAGA mediates transcription from the TATA-like element independently of Taf1p/TFIID but dependent on core promoter structures in Saccharomyces cerevisiae. PLOS ONE. 2017. 12. 11. e0188435
  • Koji Kasahara, Ayako Higashino, Satoru Unzai, Hirofumi Yoshikawa, Tetsuro Kokubo. Oligomerization of Hmo1 mediated by box A is essential for DNA binding in vitro and in vivo. GENES TO CELLS. 2016. 21. 12. 1333-1352
  • Kiyoshi Watanabe, Makoto Yabe, Koji Kasahara, Tetsuro Kokubo. A Random Screen Using a Novel Reporter Assay System Reveals a Set of Sequences That Are Preferred as the TATA or TATA-Like Elements in the CYC1 Promoter of Saccharomyces cerevisiae. PLOS ONE. 2015. 10. 6. e0129357
MISC (1):
  • 吉田 瑶子, 範 新萍, 本田 繁則, 芦田 明, 服部 元史, 松本 雅則, 大山 良文, 古久保 哲朗, 南学 正臣, 宮田 敏行, 藤村 吉博. 本邦の非典型溶血性尿毒症症候群(aHUS)の患者登録とその表現型-遺伝子型解析. 日本小児腎臓病学会雑誌. 2013. 26. 1Suppl. 143-143
Books (3):
  • Mechanisms of Transcriptional Activation and Repression
    Springer Science + Business Media LLC 2013
  • Transcription Initiation in Eukaryote
    Springer Science + Business Media 2013
  • Transcription in Eukaryote
    Springer Science + Business Media 2013
Lectures and oral presentations  (5):
  • Deletion of the N-terminal domain of TAF1 (taf1-ΔTAND) exhibits synthetic lethality with mutations of the RAM signaling network in budding yeast
  • Molecular function of HMO1 at ribosomal protein gene promoters
  • A role of the polymorphic gene SSD1 in the expression of CLN2 in Saccharomyces cerevisiae
  • Identification and characterization of functional domains of Med9 in Saccharomyces cerevisiae
Education (1):
  • - 1985 The University of Tokyo Faculty of Agriculture
Work history (1):
  • Yokohama City University International College of Arts and Sciences Medical Life Science Graduate School of Medical Life Science Department of Medical Life Science Professor
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