Rchr
J-GLOBAL ID：200901026088899188   Update date: Feb. 01, 2024

Sato Chihiro

Sato Chihiro
Affiliation and department：
Nagoya University Institute for Glyco-core Research

About Nagoya University Institute for Glyco-core Research


Job title： Professor
Homepage URL  (1)： https://www.agr.nagoya-u.ac.jp/~gls/
Research field  (6)： Functional biochemistry ,  Structural biochemistry ,  Medical biochemistry ,  Applied biochemistry ,  Applied molecular and cellular biology ,  Molecular biochemistry
Research keywords  (12)： Glycobiology ,  polysialic acid ,  sialic acid ,  acidic sugar ,  brain ,  neuron ,  mental disorder ,  schizophrenia ,  bipolar disorder ,  autism ,  raft ,  gametic cell
Research theme for competitive and other funds  (19)：
  • 2022 - 2025 脊椎動物におけるシアル酸特異的硫酸転移酵素群の発見とその生物学的重要性の証明
  • 2021 - 2025 免疫細胞レクチンシグレックの新規リガンド結合部位の証明と新しい免疫制御機構の解明
  • 2015 - 2018 ポリシアル酸による新しい細胞機能調節機構の分子基盤の解明
  • 2014 - 2017 Synthesis of chemical probes containing di/oligosialialic acids and their biological evaluation related to innate immunity
  • 2013 - 2016 Novel regulatory mechanism for intracellular calcium ion concentration by membrane microdomain-localized glycans in sperm
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Papers (135)：
  • Rina Hatanaka, Masaya Hane, Kaito Hayakawa, Sayo Morishita, Shiho Ohno, Yoshiki Yamaguchi, Di Wu, Ken Kitajima, Chihiro Sato. Identification of a buried β-strand as a novel disease-related motif in the human polysialyltransferases. Journal of Biological Chemistry. 2023. 105564-105564
  • Kaito Hayakawa, Masaya Hane, Hiroki Hamagami, Miki Imai, Hiroshi Tanaka, Ken Kitajima, Chihiro Sato. Interactions between polysialic acid and dopamine-lead compounds as revealed by biochemical and in silico docking simulation analyses. Glycoconjugate Journal. 2023. 40. 4. 461-471
  • Rina Hatanaka, Erino Araki, Masaya Hane, Shiori Go, Di Wu, Ken Kitajima, Chihiro Sato. The α2,8-sialyltransferase 6 (St8sia6) localizes in the ER and enhances the anchorage-independent cell growth in cancer. Biochemical and biophysical research communications. 2022. 608. 52-58
  • Shiori Go, Chihiro Sato, Masaya Hane, Shinji Go, Ken Kitajima. Implication of N-glycolylneuraminic acid in regulation of cell adhesiveness of C2C12 myoblast cells during differentiation into myotube cells. Glycoconjugate journal. 2022
  • Masaya Hane, Ken Kitajima, Chihiro Sato. Comprehensive Analysis of Oligo/Polysialylglycoconjugates in Cancer Cell Lines. International journal of molecular sciences. 2022. 23. 10
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MISC (24)：
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Books (19)：
  • Advanced Technologies in Sialic Acid and Sialoglycoconjugate Analysis in Top Curr Chem
    Springer 2015
  • Frontal Affinity Chromatography in the Methods in Molecular Biology
    Springer 2014
  • Flagellasialin in the Glycoscience: Biology and Medicine
    Springer 2014
  • Polysialyltransferase assay in the Glycoscience: Biology and Medicine
    Springer 2014
  • Polysialic acid in the Glycoscience: Biology and Medicine
    Springer, 2014
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Lectures and oral presentations  (37)：
  • 魚類CMP-シアル酸合成酵素の構造と性質
    (日本農芸化学会2009年度大会 2009)
  • ポリシアル酸と脳由来神経栄養因子の相互作用の解析
    (日本農芸化学会2009年度大会 2009)
  • ポリシアル酸とFGF-2の相互作用の解析.
    (日本農芸化学会2009年度大会 2009)
  • ラクタム化シアル酸誘導体の合成とその分解反応に関する研究.
    (日本農芸化学会2009年度大会 2009)
  • Polysialic acid is not a negative regulator any longer in neurogenesis and neuronal functions: A new finding of its binding to a particular group of neurotransmitters.
    (Gordon Research Conference on Glycobiology, 2009)
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Works (7)：
  • Enzyme assay of polysialyltransferase (
    2011 -
  • Carbohydrate analysis by gas-liquid chromatography
    2011 -
  • Specific labeling and chemical analysis of sialic acid and sialyloligo/polymers
    2011 -
  • Sialic acid and evolution
    2006 -
  • Function of polysialic acid in nervus system
    2004 -
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Education (3)：
  • 1994 - 1997 The University of Tokyo Graduate School, Division of Science Department of Biophysics and Biochemistry
  • 1992 - 1994 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
  • 1988 - 1992 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
Professional career (1)：
  • Ph D (The University of Tokyo)
Work history (10)：
  • 2021/01 - 現在 名古屋大学 統合生命科学糖鎖研究センター
  • 2021/01 - 現在 名古屋大学 糖鎖生命コア研究所
  • 2019/10/01 - 現在 Nagoya University Graduate School of Bioagricultural Sciences Professor
  • 2019/04/01 - 2019/09/30 Nagoya University Bioscience and Biotechnology Center Associate professor
  • 2007/04/01 - 2019/03/31 Nagoya University Bioscience and Biotechnology Center Fundamental and Incubation Division Associate professor
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Awards (4)：
  • 2017/03 - Award for Outstanding Women’s Research Activity
  • 2010/03 - Award for best paper in BBB
  • 2003/03 - Award for outstanding researcher
  • 1999/03 - JSCR Poster Award
Association Membership(s) (6)：
日本神経科学会 ,  ASBMB ,  糖鎖科学名古屋拠点 ,  日本農芸化学会 ,  日本生化学会 ,  日本糖質学会
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