Koketsu Mamoru

コウケツマモル | Koketsu Mamoru

Affiliation and department：
Job title： Professor
Other affiliations (1)：

工学研究科教授

Homepage URL (2)： https://www1.gifu-u.ac.jp/~kulab/ , https://www1.gifu-u.ac.jp/~kulab/koketsu/index_e.html

Research field (8)： Pharmaceuticals - chemistry and drug development , Green/sustainable/environmental chemistry , Pharmaceuticals - chemistry and drug development , Bioorganic chemistry , Structural/physical organic chemistry , Applied molecular and cellular biology , Biochemistry , Synthetic organic chemistry

Research keywords (35)：有機合成化学、天然物化学、機器分析 , Natural Product Chemistry , Selenium atom , 生理活性物質 , 天然物化学 , 阻害剤 , 抗生物質 , セレナザジエン , グラブズ試薬 , キシロース , テトラゾール , カルバミン酸 , 生合成阻害剤 , ヘテロ元素 , セレン導入試薬 , ヘテロ原子 , グリコサミノグリカン , セレン化合物 , β-ラクタム , グルコサミノグリカン , セレノチオカルバミン酸 , ヨウ素環化反応 , LiAlHSeH , トリアゾール , ジアシルスルフィド , ヘテロ化合物 , セレン元素 , ヘテロ化学 , 硫黄化合物 , セレン , セレナゾール , 有機合成 , セレノアミド , ヘテロ環化合物 , セレノ尿素

Research theme for competitive and other funds (13)：

2020 - 2024 Development new materials for pneumonia
2015 - 2018 Development of high efficient synthesis method of selenium neucleosides and its application
2016 - 2017 イシクラゲから抽出精製した抗酸化成分の製品化
2011 - 2013 Preparation of various xylose derivatives as glycosaminoglycan biosynthesis inhibitor
2008 - 2010 Preparation of novel beta-lactam derivatives using efficient leaving group

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Papers (290)：

Rei Funahashi, Fumiaki Matsuura, Masayuki Ninomiya, Sayo Okabe, Shigeo Takashima, Kaori Tanaka, Atsuyoshi Nishina, Mamoru Koketsu. Hybrid pharmacophore design and synthesis of donepezil-inspired aurone derivative salts as multifunctional acetylcholinesterase inhibitors. Bioorganic chemistry. 2024. 145. 107229-107229
Atsuyoshi Nishina, Motohiko Ukiya, Kazuki Motegi, Risa Kiryu, Daisuke Sato, Mitsuru Sada, Yuki Hori, Hideo Satsu, Kazuhiro Uemura, Mamoru Koketsu, et al. Promotion of ABCG2 gene expression by neolignans from Piper longum L. Bioscience, Biotechnology, and Biochemistry. 2023. in press
Tomohiro Itoh, Mai Muramatsu, Daiki Miyazono, Mamoru Koketsu, Shingo Fujita, Toshiharu Hashizume. Phenolic Glycosides Citrulluside H and Citrulluside T Isolated From Young Watermelon (Citrullus lanatus) Fruit Have Beneficial Effects Against Cutibacterium acnes-Induced Skin Inflammation. Natural Product Communications. 2023. 18. 1. 1934578X2211432-1934578X2211432
Takahiro Kobayashi, Norika Tanaka, Mayu Suzuki, Miwa Maeda, Irmanida Batubara, Dyah Iswantini, Mamoru Koketsu, Akie Hamamoto, Hiroshi Takemori. Adenostemmoic acid B suppresses NO production by downregulating the expression and inhibiting the enzymatic activity of iNOS. Phytochemistry Letters. 2022. 49. 131-137
Thi-Kim-Dung Le, Ade Danova, Thammarat Aree, Thuc-Huy Duong, Mamoru Koketsu, Masayuki Ninomiya, Yoshiharu Sawada, Pharit Kamsri, Pornpun Pungpo, Warinthorn Chavasiri. α-Glucosidase Inhibitors from the Stems of Knema globularia. Journal of Natural Products. 2022. 85. 4. 776-786

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MISC (280)：

Amol D. Sonawane, Mamoru Koketsu. Organocatalysed synthesis of selenium containing scaffolds. Current Organocatalysis. 2021. 8. 1. 5-26
Amol D. Sonawane, Rohini A. Sonawane, Masayuki Ninomiya, Mamoru Koketsu. Synthesis of Seleno-Heterocycles via Electrophilic/Radical Cyclization of Alkyne Containing Heteroatoms. Advanced Synthesis and Catalysis. 2020. 362. 17. 3485-3515
Amol D. Sonawane, Mamoru Koketsu. Recent advances on c-se bond-forming reactions at low and room temperature. Current Organic Chemistry. 2019. 23. 28. 3206-3225
A. Nishina, M. Ukiya, M. Fukatsu, M. Koketsu, M. Ninomiya, D. Sato, H. Kimura. 5,7-Dihydroxyflavone analogues may regulate lipopolysaccharide-induced inflammatory responses by suppressing I kappa B alpha-linked Akt and ERK5 phosphorylation in RAW 264.7 macrophages. PLANTA MEDICA. 2016. 82
Kenichi Komura, Yuta Mishima, Mamoru Koketsu. Organic amine grafting on mesoporous silica as a hybrid catalyst for heterogeneous three-component one-pot reaction. APPLIED CATALYSIS A-GENERAL. 2012. 445. 128-132

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Patents (51)：

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Books (16)：

楽しく学ぶくらしの化学 : 生活に生かせる化学の知識
化学同人 2021 ISBN:9784759820553
Selenoureas and their applications in Organoselenium chemistry
De Gruyter 2020 ISBN:9783110622249
Role of isoselenocyanates for the synthesis of selenium-containing heterocycles in Organoselenium chemistry
De Gruyter 2020 ISBN:9783110622249
Synthesis of organoselenium scaffolds through selenium radical formation in Organoselenium chemistry
De Gruyter 2020 ISBN:9783110622249
Synthesis of selective inhibitors of heparan sulfate and chondroitin sulfate proteoglycan biosynthesis in Methods in molecular biology
Springer New York 2015

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Professional career (1)：

Ph.D. (Mie University)

Work history (15)：

2013/04 - 現在 Gifu Universty Faculty of Engineering Professor
2022/04 - 2024/03 Gifu University
2018/03 - 2024/03 Gifu University
2020/04 - 2022/03 Gifu University
2018/04 - 2020/03 Gfu University Adviser to the President

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Committee career (5)：

2007 - 現在日本油化学会東海支部常任幹事
2020/04 - 2022/03 日本油化学会副会長・代表理事
2000/04 - 2022/03 日本油化学会副会長、年会実行委員長
2010 - 2012 日本化学会東海支部常任幹事
2004/09 - 2008/02 有機合成化学協会東海支部常任幹事

Awards (2)：

2001 - 有機合成化学協会東海支部奨励賞
1994 - 工業技術賞

Association Membership(s) (4)：

Japan Oil Chemists'Society , The Society of Synthetic Organic Chemistry, Japan , The Chemical Society of Japan , 日本栄養・食糧学会

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