Rchr
J-GLOBAL ID:200901026643356543   Update date: Sep. 18, 2024

Taguchi Keiko

タグチ ケイコ | Taguchi Keiko
Affiliation and department:
Job title: Associate Professor
Homepage URL  (2): http://db.tohoku.ac.jp/whois/detail/c614d4b07ee6f608b86107caed7dd292.htmlhttp://db.tohoku.ac.jp/whois/e_detail/c614d4b07ee6f608b86107caed7dd292.html
Research field  (3): Food sciences ,  Medical biochemistry ,  Pharmaceuticals - health and biochemistry
Research keywords  (3): 食品化学 ,  衛生薬学 ,  Biochemistry
Research theme for competitive and other funds  (15):
  • 2022 - 2025 肝臓の組織構築におけるNrf2の新たな機能
  • 2022 - 2025 硫黄生物学から紐解く膵癌難治化機構の解明と治療応用
  • 2019 - 2024 Deciphering Molecular Basis for the Anti-Oxidative Stress Response and Application of the Basis for Disease Prevention and Therapy
  • 2019 - 2022 Development of esophagus cancer acquired Nrf2 activation
  • 2019 - 2022 Development of novel therapy for pancreatic cancer based on the regulation of oxidative stress responses
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Papers (92):
  • Yu-Ichi Aoki, Keiko Taguchi, Hayato Anzawa, Junko Kawashima, Noriko Ishida, Akihito Otuki, Atsushi Hasegawa, Liam Baird, Takafumi Suzuki, Ikuko N Motoike, et al. Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals. Journal of biochemistry. 2024
  • Xinying Ye, Takashi Toyama, Keiko Taguchi, Kotoko Arisawa, Takayuki Kaneko, Ryouhei Tsutsumi, Masayuki Yamamoto, Yoshiro Saito. Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2. Communications Biology. 2023. 6. 1. 1060-1060
  • Liam Baird, Keiko Taguchi, Anqi Zhang, Yushi Takahashi, Takafumi Suzuki, Thomas W. Kensler, Masayuki Yamamoto. A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells. Redox Biology. 2023. 66. 102845-102845
  • Marta Anna Kowalik, Keiko Taguchi, Marina Serra, Andrea Caddeo, Elisabetta Puliga, Marina Bacci, Seizo Koshiba, Jin Inoue, Eiji Hishinuma, Andrea Morandi, et al. Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes. Hepatology (Baltimore, Md.). 2023. 79. 4. 829-843
  • Shimizu R, Hirano I, Hasegawa A, Suzuki M, Otsuki A, Taguchi K, Katsuoka F, Uruno A, Suzuki N, Yumoto A, et al. Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice. Commun Biol. 2023. 6. 1. 875-875
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MISC (33):
Books (6):
  • 酸化ストレスの医学改訂第2版
    診断と治療社 2014
  • 毒性の科学:分子・細胞から人間集団まで
    東京大学出版会 2014
  • Protein modifications in pathogenic dysregulation of signaling
    Springer 2014
  • 実験医学増刊号
    羊土社 2012
  • 実験医学増刊号
    羊土社 2012
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Lectures and oral presentations  (72):
  • Nrf2の活性制御破綻がもたらす肝病態
    (第87回日本生化学会大会 2014)
  • Liver diseases caused by perturbation of Nrf2 regulation
    (第73回日本癌学会学術総会 2014)
  • Two-step regulation of Nrf2 activity in the liver
    (フォーラム2014衛生薬学・環境トキシコロジー 2014)
  • 転写因子Nrf2の活性制御メカニズムと病態
    (転写若手放射線生物学研究会勉強会 2014)
  • Molecular Mechanisms and Functions of Keap1-Nrf2 system
    (2014 International Symposium and Annual Meeting of the KSABC (The Korean Society for Applied Biological Chemistry) 2014)
more...
Professional career (1):
  • Ph.D. in Medicine (University of Tsukuba)
Work history (5):
  • 2023/06 - 現在 Tohoku Medical Megabank Organization, Tohoku University Visiting Associate Professor
  • 2023/06 - 現在 Graduate School of Agricultural and Life Sciences, The University of Tokyo Laboratory of Food Chemistry, Department of Applied Biological Chemistry Associate Professor
  • 2017/04 - 2020/03 Tohoku University Graduate School of Medicine Senior Assistant Professor
  • 2008/01 - 2017/03 Tohoku University Graduate School of Medicine Assistant Professor
  • 2006/04 - 2007/12 科学技術振興機構 JST-ERATO山本環境応答プロジェクト 技術員・研究員
Committee career (6):
  • 2022/12 - 現在 The Japanese Society of Toxicology Executive board member
  • 2022/07 - 現在 The Japanese Society of Toxicology ASIATOX
  • 2021/10 - 現在 ASIATOX Councilor Councilor
  • 2020/04 - 現在 宮城県 環境影響評価技術審査会
  • 2016/04 - 2019/03 日本薬学会 環境・衛生部会 研究戦略委員会委員
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Awards (9):
  • 2020/01 - 東北大学医学部 東北大学医学部奨学賞(金賞) Keap1-Nrf2システムによる生体機能制御機構の解明
  • 2017/07 - The Japanese Scociety of Toxicology The JSOT Young Scientist Award
  • 2016/07 - The Naito Foundation 41st Naito Conference Poster Award Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy
  • 2015/12 - Japanese Biochemical Society Young Investigator Award
  • 2013/09 - 倶進会・日本生化学会 第10回柿内三郎記念奨励研究賞
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Association Membership(s) (6):
Japan Scoety for Bioscience, Biotechnology, and Agrochemistry ,  Sociey of Toxicology ,  日本生化学会(2009/09-) ,  日本癌学会(2009/02-) ,  日本毒性学会(2007/01-) ,  日本薬学会(2004/02-)
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