Rchr
J-GLOBAL ID：200901026747824859   Update date: Jun. 26, 2024

Hosokawa Yoshitaka

ホソカワ ヨシタカ | Hosokawa Yoshitaka
Affiliation and department：
The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School, Department of Conservative Dentistry

About The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School, Department of Conservative Dentistry


Job title： Research Associate
Research field  (1)： Conservative dentistry and endodontics
Research keywords  (4)： 免疫 ,  歯周病 ,  Immunology ,  periodontitis
Research theme for competitive and other funds  (23)：
  • 2022 - 2026 ワサビ含有成分を歯周炎治療に用いるための基礎的研究~抗炎症作用に着目して~
  • 2022 - 2026 乳酸菌由来細胞外小胞を用いた歯周病治療戦略ーM1/M2マクロファージに着目してー
  • 2022 - 2025 ポリフェノール内包キトサンナノカプセルを用いた口腔バイオフィルム抑制技術の開発
  • 2019 - 2022 口腔バイオフィルムの分散能と抗菌能を有する光触媒・ポリフェノール合剤の新規開発
  • 2019 - 2022 柑橘類果皮含有生理活性物質を歯周炎治療に用いるための基礎的研究
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Papers (67)：
  • Risa Okamoto, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Keiichi Hosaka. Cardamonin inhibits the expression of inflammatory mediators in TNF-α-stimulated human periodontal ligament cells. Immunopharmacology and immunotoxicology. 2024. 1-30
  • Yoshitaka Hosokawa, Ikuko Hosokawa, Masahiro Shimoyama, Risa Okamoto, Kazumi Ozaki, Keiichi Hosaka. The effects of berteroin on inflammatory mediators and antioxidant enzymes expression in human periodontal ligament cells. Naunyn-Schmiedeberg's archives of pharmacology. 2024. 397. 4. 2233-2240
  • Masahiro Shimoyama, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Keiichi Hosaka. Effects of erucin on inflammatory mediators and antioxidant enzymes' expression in TNF-α-stimulated human oral epithelial cells. Immunopharmacology and immunotoxicology. 2024. 46. 1. 49-54
  • Risa Okamoto, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Keiichi Hosaka. Cardamonin decreases inflammatory mediator expression in IL-1β-stimulated human periodontal ligament cells. Molecular biology reports. 2024. 51. 1. 222-222
  • Yoshitaka Hosokawa, Ikuko Hosokawa, Masahiro Shimoyama, Ayumi Fujii, Juri Sato, Kimitake Kadena, Kazumi Ozaki, Keiichi Hosaka. The Anti-Inflammatory Effects of Iberin on TNF-α-Stimulated Human Oral Epithelial Cells: In Vitro Research. Biomedicines. 2022. 10. 12
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MISC (22)：
  • HOSOKAWA Yoshitaka, HOSOKAWA Ikuko, OZAKI Kazumi, NAKAE Hideaki, MATSUO Takashi. Effects of flagellin on cytokine production and adherent molecule expression by human gingival fibroblasts. 2008. 51. 160-160
  • HOSOKAWA Ikuko, HOSOKAWA Yoshitaka, OZAKI Kazumi, NAKAE Hideaki, MATSUO Takashi. The effects of adrenomedullin on IL-1beta production by toll-like receptor ligands-stimulated human monocytes. 2008. 51. 103-103
  • The study of Chemokines in Periodontal Diseases and Regulation of its Expression. 2008. 20. 2. 235-239
  • MUKAI Kayo, NAKANISHI Tadashi, HOSOKAWA Yoshitaka, TAKAHASHI Kanako, MATSUO Takashi. Expression of Cytokines and Adhesion Molecules in Cultured Dental Pulp Fibroblasts Affected by Bacteria-derived Factors. 2007. 50. 5. 553-561
  • HOSOKAWA Ikuko, HOSOKAWA Yoshitaka, OZAKI Kazumi, NAKAE Hideaki, MATSUO Takashi. Effects of adrenomedullin on cytokine production by human gingival fibroblasts. 2007. 50. 132-132
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Lectures and oral presentations  (65)：
  • Nobiletinはヒト歯根膜由来細胞のIL-1β誘導炎症性メディエーター産生を抑制する
    (日本歯科保存学会2021年度春季学術大会 2020)
  • Carnosic Acidはヒト歯根膜由来細胞のIL-1β誘導炎症性サイトカイン産生を抑制する
    (日本歯科保存学会2020年度春季学術大会 2020)
  • Sudachitinはヒト歯根膜由来細胞のIL-1β誘導炎症性メディエーター産生を抑制する
    (日本歯科保存学会2020年度春季学術大会 2020)
  • Carnosic Acidはヒト口腔上皮細胞のIL-27誘導CXCR3リガンド産生を抑制する
    (日本歯科保存学会2018年度秋季学術大会 2018)
  • IL-27 induces CXCR3 ligands production in human oral epithelial cells
    (第61回日本歯周病学会春季学術大会 2018)
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Professional career (1)：
  • Ph. D (Tokushima University Graduate School)
Work history (5)：
  • 2018/02 - 現在 The University of Tokushima
  • 2015/04 - 2018/01 徳島大学大学院医歯薬学研究部 歯科保存学分野 助教
  • 2006/04 - 2015/03 The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School
  • 2004/04 - 2006/03 The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School
  • 2002/02 - 2004/03 The Forsyth Institute Department of Immunology postdoctoral fellow
Awards (6)：
  • 2019/06 - 日本歯科保存学会 2019年度日本歯科保存学会学術賞
  • 2014/10 - 日本歯周病学会 日本歯周病学会学術賞
  • 2008/06 - 日本歯科保存学会 日本歯科保存学会奨励賞
  • 2007/02 - 徳島大学歯学部 西野瑞穂歯科臨床医学奨励賞
  • 2004/05 - 日本歯周病学会 日本歯周病学会奨励賞
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Association Membership(s) (5)：
国際歯科研究学会 ,  四国歯学会 ,  JAPANESE ASSOCIATION FOR DENTAL RESEARCH ,  THE JAPANESE SOCIETY OF CONSERVATIVE DENTISTRY ,  日本歯周病学会
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