Research field (5)：
Chemical biology
, Synthetic organic chemistry
, Molecular biochemistry
, Pharmaceuticals - chemistry and drug development
, Bioorganic chemistry
2018 - 2021 Nitrogen Signaling Factor (NSF)-mediated cell-to-cell communication in fission yeast
2018 - 2021 Synthetic chemistry for the development of oligosaccharide-type sialidase inhibitors
2018 - 2019 代謝安定型糖鎖を基盤とする高次生物機能中分子複合糖質アナログ創製
2016 - 2019 糖脂質の代謝と分子相互作用を解明する分子ツール創製
2019 - 公益財団法人 内藤記念科学振興財団 内藤記念科学奨励金・研究助成
2018 - 公益財団法人 柿原科学技術研究財団 科学技術研究助成
2018 - 公益財団法人 武田科学振興財団 薬学系研究助成
2016 - 2017 代謝安定型糖鎖を基盤とする高次生物機能複合糖質アナログの創製
2015 - 2017 Development of a novel type of carbohydrate probes
2017 - 公益財団法人 長瀬科学技術振興財団 助成金
2017 - 公益財団法人 上原記念生命科学財団 研究推進特別奨励金
2016 - 公益財団法人東京生化学研究会
2013 - 2015 Structural study of reconstitued full length PKC
2014 - 2015 酸化ステロイドの鍵構造アナログ創製と作用機序解析
2013 - 2014 タンパク質SUMO化を阻害する天然物リガンドの合成供給と構造活性相関
2011 - 2013 Study on chemical biology for protein SUMOylation
2010 - 2012 Synthetic approaches toward the identification of target proteins of physalins
2009 - 2011 Clarification research for molecular mechanism of a novel type of protein kinase C inhibitor
2009 - 2011 Proteomic approach for identification of lysine acetylation in bacteria
2007 - 2008 Development of a novel type of irreversible inhibitors for comprehensive analysis of protein phosphatase in cells
2004 - 2007 細胞の増殖と死を制御する分子の創製と機能解析
2004 - 2005 プロテインキナーゼC活性化機構の解明と新規阻害剤の開発
2003 - 2004 Construction of focused library and the development of protein tyrosine phosphatase inhibitor
2002 - 2003 酵素のコンホメーションを認識する分子:阻害剤開発への新しいアプローチ
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Papers (97)：
Shin Ohsawa, Michaela Schwaiger, Vytautas Iesmantavicius, Rio Hashimoto, Hiromitsu Moriyama, Hiroaki Matoba, Go Hirai, Mikiko Sodeoka, Atsushi Hashimoto, Akihisa Matsuyama, et al. Nitrogen signaling factor triggers a respiration-like gene expression program in fission yeast. The EMBO Journal. 2024
Natsuho Moritsuka, Noriaki Kiya, Takahiro Moriyama, Hiroyuki Koshino, Makoto Yoritate, Hiroaki Matoba, Go Hirai. Linkage-Editing of Melibiosamine: Synthesis and Biological Evaluation of CH2- and CHF-Linked Analogs. The Journal of Organic Chemistry. 2024
Hiroaki Matoba, Kouhei Oba, Huanlin Li, Yuta Mizuno, Qianqian Wang, Makoto Yoritate, Mariko Aso, Mikiko Sodeoka, Minoru Yoshida, Yoko Yashiroda, et al. Structure-activity relationship study of nitrogen signaling factors. Bioorganic & Medicinal Chemistry Letters. 2024. 109. 129857-129857
Noyuri Kudo, Suzuka Chiba, Kazuteru Usui, Go Hirai, Shunsuke Ono, Masataka Nagatoishi, Makoto Yoritate, Satoru Karasawa. Stereoselective Synthesis of C-Aryl-α-Glycosides by Reductive C(sp2)-C(sp3) Cross-Coupling Reaction. Synlett. 2024
Takahiro Moriyama, Makoto Yoritate, Naoki Kato, Azusa Saika, Wakana Kusuhara, Shunsuke Ono, Takahiro Nagatake, Hiroyuki Koshino, Noriaki Kiya, Natsuho Moritsuka, et al. Linkage-editing pseudo-glycans: A reductive α-fluorovinyl-C-glycosylation strategy to create glycan analogs with altered biological activities. Journal of the American Chemical Society. 2024
2002/04 - 2004/09 Tohoku University IMRAM Assistant Professor
Committee career (4)：
2022/04 - 2024/03 有機合成化学協会 九州山口支部 幹事
2022/04 - 万有福岡シンポジウム組織委員会 委員
2019/01 - 2022/01 日本薬学会医薬化学部会 常任世話人
2020/04 - 日本糖質学会 評議員
Awards (7)：
2017/04 - 公益財団法人 長瀬科学技術振興財団 長瀬振興研究奨励賞
2014/11 - Thieme Chemistry - Georg Thieme Verlag Thieme Chemistry Journal Award 2015
2014/11 - GLYCOTOKYO GLYCOTOKYO2014奨励賞
2014/02 - 有機合成化学協会 2013年度有機合成化学奨励賞
2010/11 - The 5th International Conference on Cutting-Edge Organic Chemistry in Asia /The 1st New Phase International Conference on Cutting-Edge Organic Chemistry in Asia Asian Core Program Lectureship Award
