Rchr
J-GLOBAL ID:200901027073006981
Update date: Oct. 29, 2024
TAKASHI IWAI
Iwai Takashi | TAKASHI IWAI
Affiliation and department:
Job title:
Lecturer/Junior Associate Professor
Research field (3):
Pharmaceuticals - health and biochemistry
, Neuroscience - general
, Psychiatry
Research keywords (6):
δ opioid
, chronic stress
, Cognitive function
, GABA
, Antidepressant
, Glucagon-like peptide
Research theme for competitive and other funds (4):
- 2020 - 2023 うつ病の認知機能障害に対する治療法の解明:δオピオイド受容体を介した改善機序
- 2010 - 2012 Prg1, regulated by MATH2, is an important factor for survival of neurons derived from neural stem cells
- 2010 - 2012 Gene expression analysis in ventral and dorsal hippocampal dentate gyrus after 4 weeks treatment with sertraline
- 2011 - 2011 うつ病治癒メカニズム解明に向けた神経新生におけるrhotekinの機能解析
Papers (49):
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Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Selective inhibition of A-fiber-mediated excitatory transmission underlies the analgesic effects of KCNQ channel opening in the spinal dorsal horn. Neuropharmacology. 2024. 254. 109994-109994
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Ryosuke Nakamura, Takashi Iwai, Yasukazu Takanezawa, Tatsuya Shirahata, Naruki Konishi, Yuka Ohshiro, Shimpei Uraguchi, Mitsuo Tanabe, Yoshinori Kobayashi, Kenji Sakamoto, et al. Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice. Toxicology. 2024. 506. 153867-153867
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Takashi Iwai, Rei Mishima, Shigeto Hirayama, Honoka Nakajima, Misa Oyama, Shun Watanabe, Hideaki Fujii, Mitsuo Tanabe. SYK-623, a δ Opioid Receptor Inverse Agonist, Mitigates Chronic Stress-Induced Behavioral Abnormalities and Disrupted Neurogenesis. Journal of Clinical Medicine. 2024. 13. 2. 608-608
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Motoki Morita, Shun Watanabe, Natsumi Nomura, Kanako Takano-Matsuzaki, Misa Oyama, Takashi Iwai, Mitsuo Tanabe. Sulfatide-selectin signaling in the spinal cord induces mechanical allodynia. Journal of neurochemistry. 2022
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Junpei Takahashi, Yudai Ueta, Daisuke Yamada, Sachie Sasaki-Hamada, Takashi Iwai, Tomomi Akita, Chikamasa Yamashita, Akiyoshi Saitoh, Jun-Ichiro Oka. Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve β-amyloid peptide (25-35)-induced memory impairment in mice. Neuropsychopharmacology reports. 2022
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MISC (36):
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丹野 真由香, 中村 亮介, 高根沢 康一, 大城 有香, 浦口 晋平, 白畑 辰弥, 小西 成樹, 岩井 孝志, 小林 義典, 田辺 光男, et al. Dynamic weight bearing testを用いたMeHg毒性の評価. 日本薬学会年会要旨集. 2020. 140年会. 28Q-am145S
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丹野真由香, 中村亮介, 高根沢康一, 大城有香, 浦口晋平, 白畑辰弥, 小西成樹, 岩井孝志, 小林義典, 田辺光男, et al. Evaluation of MeHg toxicity using dynamic weight bearing test. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
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中村亮介, 岩井孝志, 白畑辰弥, 小西成樹, 高根沢康一, 大城有香, 浦口晋平, 田辺光男, 小林義典, 清野正子. Oleanolic acid-3-glucoside, a synthetic oleananetype saponin, ameliorates methylmercury-induced neurotoxicity in vivo. Journal of Toxicological Sciences. 2020. 45. Supplement
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中村亮介, 高根沢康一, 曽根有香, 浦口晋平, 白畑辰弥, 岩井孝志, 小林義典, 田辺光男, 清野正子. メチル水銀による神経伝達障害に対するオレアノール酸3-グルコシドの効果. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
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宿利 美香, 大内 彩子, 内藤 康仁, 岩井 孝志, 渡辺 俊, 尾山 実砂, 植松 智, 審良 静男, Jakobsson Per-Johan, 田辺 光男, et al. mPGES-1阻害薬のマウス脳梗塞障害改善機序. 日本薬学会年会要旨集. 2018. 138年会. 3. 95-95
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Lectures and oral presentations (87):
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海馬-側坐核系の保護によるδオピオイド受容体逆作動薬SYK-623の抗うつ作用
(第53回日本神経精神薬理学会年会 2023)
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P2X7受容体作動薬BzATPの不安惹起作用
(第42回鎮痛薬・オピオイドペプチドシンポジウム 2023)
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δオピオイド受容体作動薬KNT-127の睡眠に対する作用
(第42回鎮痛薬・オピオイドペプチドシンポジウム 2023)
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うつ病の無快感発症機序における腹側海馬GABA神経障害の関与
(第148回日本薬理学会関東部会 2023)
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Effects of KNT-127, a delta opioid receptor agonist, on non-REM sleep in mice.
(2022)
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Education (2):
- 1999 - 2001 Meijo University Graduate School, Division of Pharmaceutical Sciences Clinical Pharmacy
- 1995 - 1999 Meijo University Faculty of Pharmaceutical Science Department of Pharmaceutical Sciences
Professional career (1):
- PhD (Tokyo University of Science)
Work history (4):
- 2013/04 - Kitasato University Laboratory of Pharmacology
- 2011/11 - 2013/03 Kitasato University Laboratory of Medicinal Chemistry, School of Pharmacy
- 2008/10 - 2011/10 National Center of Neurology and Psychiatry Department of Neuropsychopharmacology
- 2001/04 - 2008/09 Tokyo University of Science Department of Pharmacology
Committee career (2):
- 2017/04/01 - 日本薬学会 ファルマシアトピックス小委員会
- 2015/04/01 - 日本薬理学会 学術評議員
Association Membership(s) (4):
日本薬理学会
, 日本神経精神薬理学会
, 日本薬学会
, 日本神経科学会
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