Rchr
J-GLOBAL ID：200901027126933774
Update date: Aug. 26, 2024
Morita Hiroshi
モリタ ヒロシ | Morita Hiroshi
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://polaris.hoshi.ac.jp/kyoshitsu/shouyaku/shouyaku.html
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (3)：
生薬学
, 天然物化学
, Natural product chemistry
Research theme for competitive and other funds (26)：
- 2022 - 2025 Research of medicinal seeds by elucidating the structural diversity and function of polycyclic multimeric natural products
- 2019 - 2022 Research of polycyclic alkaloids from plants towards new biologically active substances
- 2016 - 2019 Research on seeds from unique ring skeletal limonoids for drug discovery
- 2013 - 2016 Research for natural products including alkaloids that inhibit TRP channels
- 2005 - 2007 Research for Antitumor Crude Drug from Malaysian Unutilized Plant Resorces
- 2005 - 2006 Research of Bioactive Alkaloids with Polycyclic Skeletons
- 2004 - 2005 Research and development of bioactive natural products targeting cytoskeleton.
- 2002 - 2003 Search for New Natural Products from Unutilized Northern Plants
- 2002 - 2002 チューブリンを分子標的とした抗腫瘍性植物成分の探索と開発
- 2000 - 2001 Search for New Natural Products from Unutilized North Line Plant Biomass
- 1999 - 2001 Research for utilization of unused natural resources
- 2000 - 2000 植物由来の環状ペプチドを素材とした新しい抗がん剤の探索
- 1997 - 2000 Development Research for Bio-active Cyclic Peptides from Plant Sources
- 1994 - 1996 Studies on Antitumor Cyclic Oligopeptides from Higher Plants
- 1995 - 1995 チロシナーゼ阻害活性を有する環状ペプチドに関する研究
- 1994 - 1994 抗腫瘍性環状ペプチド,Astin類のコンホメーション及び活性相関に関する研究
- 1992 - 1992 抗腫瘍性環状ヘキサペプチド,RA類のコンホメーションと活性に関する研究
- 1991 - 1991 抗腫瘍活性オリゴペプチド構成アミノ酸の立体的差異による活性差について
- 1989 - 1989 抗がん性環状ペプチドの構造活性相関
- 熱帯未利用植物資源を用いた有用物質の探索研究
- 医薬資源としての北方系植物成分の探索と開発
- 生理活性ペプチドに関する研究
- Research for novel principle from the north line plant biomass
- Study on bioactive peptides
- 多環性天然物の構造と生物活性を基盤とした医薬シードの創製
- 多環性アルカロイドを用いた新機能性分子の創製
Show all
Papers (265)：
-
Yusuke Hirasawa, Yusuke Kakizoe, Takahiro Tougan, Nahoko Uchiyama, Toshihiro Horii, Hiroshi Morita. Vincarostine A, a novel anti-malarial trimeric monoterpenoid indole alkaloid from Catharanthus roseus. Journal of Natural Medicines. 2024. 78. 3. 768-773
-
Yuki Nakajima, Naohide Tsuboi, Kumiko Katori, Maigunuer Waili, Alfarius Eko Nugroho, Kazunori Takahashi, Hitomi Nishino, Yusuke Hirasawa, Yoko Kawasaki, Yukihiro Goda, et al. Oxomollugin, an oxidized substance in mollugin, inhibited LPS-induced NF-κB activation via the suppressive effects on essential activation factors of TLR4 signaling. Journal of Natural Medicines. 2024. 78. 3. 568-575
-
Yusuke Hirasawa, Ayaka Kase, Akie Okamoto, Keigo Suzuki, Mizuki Hiroki, Toshio Kaneda, Nahoko Uchiyama, Hiroshi Morita. Vincazalidine A, a unique bisindole alkaloid from Catharanthus roseus. Journal of Natural Medicines. 2024. 78. 2. 382-392
-
Alfarius Eko Nugroho, Tomoyuki Komuro, Takuya Kawaguchi, Yusuke Shindo, Chin Piow Wong, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, A Hamid A Hadi, et al. Ceramicines U-Z from Chisocheton ceramicus and structure-antimalarial activity relationship study. Journal of natural medicines. 2023
-
Mizuki Hiroki, Aishanjiang Abulikemu, Chihiro Totsuka, Yusuke Hirasawa, Toshio Kaneda, Hiroshi Morita. Isovincathicine from Catharanthus roseus induces apoptosis in A549 cells. Journal of Natural Medicines. 2023
ｍore...
MISC (344)：
-
廣木美月, ABULIKEMU Aishanjiang, 戸塚千尋, 平澤祐介, 金田利夫, 森田博史. ニチニチソウから単離された二量体アルカロイドisovincathicineの細胞増殖阻害作用. 日本生薬学会年会講演要旨集. 2022. 68th
-
出嶋堪哉, WONG Chin Piow, NUGROHO Alfarius Eko, 小泉瑤華, 金田利夫, 平澤祐介, 森田博史. Chisocheton ceramicusより単離されたceramicine Bの酸化ストレス応答. 日本生薬学会年会講演要旨集. 2022. 68th
-
WAILI Maigunuer, 中嶋祐輝, 坪井尚秀, 香取久美子, NUGROHO Alfarius Eko, 平澤祐介, 高橋万紀, 川崎洋子, 合田幸広, 金田利夫, et al. OxomolluginのNF-κBシグナル阻害作用に関する検討. 日本生薬学会年会講演要旨集. 2021. 67th
-
谷口 裕太, 山本 憲男, 林 克洋, 武内 章彦, 三輪 真嗣, 五十嵐 健太郎, 米澤 宏隆, 亀井 淳三, 金田 利夫, 森田 博史, et al. 骨巨細胞腫に対するcyclolinopeptideの抗腫瘍効果の検討. 日本整形外科学会雑誌. 2019. 93. 8. S1680-S1680
-
中嶋祐輝, 坪井尚秀, 香取久美子, NUGROHO Alfarius Eko, 平澤祐介, 川崎洋子, 合田幸広, 金田利夫, 森田博史. Oxomollugin誘導体の抗炎症作用. 日本生薬学会年会講演要旨集. 2019. 66th
ｍore...
Education (4)：
- - 1988 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy
- - 1988 Tokyo University of Pharmacy and Life Science Graduate School, Division of Pharmaceutical Sciences
- - 1983 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
- - 1983 Tokyo University of Pharmacy and Life Science Faculty of Pharmaceutical Science
Professional career (1)：
- (BLANK) (Tokyo University of Pharmacy and Life Science)
Work history (6)：
Awards (2)：
- 2008 - 日本生薬学会学術貢献賞
- 1997 - 日本生薬学会学術奨励賞
Association Membership(s) (5)：
THE JAPAN SOCIETY FOR ORIENTAL MEDICINE
, 癌分子標的研究会
, 日本癌学会
, 日本生薬学会
, 日本薬学会
