Mio Kazuhiro

ミオカズヒロ | Mio Kazuhiro

Affiliation and department：
Homepage URL (1)： https://unit.aist.go.jp/operando-oil/

Research field (1)： Structural biochemistry

Research keywords (4)：イオンチャネル , 構造生物学 , X線1分子追跡法 , 電子顕微鏡

Research theme for competitive and other funds (9)：

2023 - 2026 X線を用いた高速1分子運動解析による膜タンパク質オペランド計測の実現
2021 - 2024 Structural analyses of PMP22 and MPZ to elucidate the molecular mechanism of Charcot-Marie-Tooth disease
2018 - 2021 Structural analyses of PMP22 and MPZ to reveal the molecular basis of Charcot-Marie-Tooth disease
2017 - 2019 1分子運動解析によるレドックス感受性TRPの分子運動基盤
2014 - 2016 TRPチャネルをターゲットとする天然物リガンドのマルチモーダル活性化機構

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Papers (123)：

Daisuke Sasaki, Tatsuya Arai, Yue Yang, Masahiro Kuramochi, Wakako Furuyama, Asuka Nanbo, Hiroshi Sekiguchi, Nobuhiro Morone, Kazuhiro Mio, Yuji C. Sasaki. Micro-second time-resolved X-ray single-molecule internal motions of SARS-CoV-2 spike variants. Biochemistry and Biophysics Reports. 2024. 38. 101712-101712
Kazuhiro Mio, Tatsunari Ohkubo, Daisuke Sasaki, Mayui Sugiura, Kayoko Kawaguchi, Kazutaka Araki, Keizaburo Taninaka, Masaki Sakaguchi, Shunsuke Nozawa, Tatsuya Arai, et al. Simultaneous Recording of Remote Domain Dynamics in Membrane Proteins Using the Double-Labeled DXB/DXT Technique. Membranes. 2024. 14. 4. 75-75
Yue Yang, Tatsuya Arai, Daisuke Sasaki, Masahiro Kuramochi, Hidetoshi Inagaki, Sumiko Ohashi, Hiroshi Sekiguchi, Kazuhiro Mio, Tai Kubo, Yuji C. Sasaki. Real-time tilting and twisting motions of ligand-bound states of α7 nicotinic acetylcholine receptor. European Biophysics Journal. 2024. 53. 1-2. 15-25
Masahiro Kuramochi, Ibuki Sugawara, Yoichi Shinkai, Kazuhiro Mio, Yuji C Sasaki. Time-Resolved X-ray Observation of Intracellular Crystallized Protein in Living Animal. International journal of molecular sciences. 2023. 24. 23
Tatsuya Arai, Kazuhiro Mio, Hiroki Onoda, Leonard M. G. Chavas, Yasufumi Umena, Yuji C. Sasaki. The Blinking of Small-Angle X-ray Scattering Reveals the Degradation Process of Protein Crystals at Microsecond Timescale. International Journal of Molecular Sciences. 2023. 24. 23. 16640-16640

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MISC (43)：

倉持昌弘, 新井達也, 三尾和弘, 津田栄, 佐々木裕次. Ice-binding proteins improve the survival rate of the nematode Caenorhabditis elegans at freezing and cold environments. アグリバイオ. 2023. 6. 14
新井達也, 新井達也, 坂口正紀, 三尾和弘, 佐々木裕次, 佐々木裕次. Observation of the rotational motion of particles in vulcanized natural rubber with the Diffracted X-ray Blinking method. 量子ビームサイエンスフェスタ(Web). 2023. 2022
谷中慶三郎, 大久保達成, 大久保達成, 新井達也, 野澤俊介, 関口博史, 古山若呼, 南保明日香, 三尾和弘, 三尾和弘, et al. Molecular dynamics of cell membrane in Ebola virus proliferation using Diffracted X-ray Blinking. 量子ビームサイエンスフェスタ(Web). 2023. 2022
稲益礼奈, 山口央基, 新井達也, 引田理英, 三尾和弘, 佐々木裕次, 佐々木裕次. Molecular Motion Measurements on Fluoroalkyl Acrylate Polymer Surface. 量子ビームサイエンスフェスタ(Web). 2023. 2022
李卓起, 大久保達成, 椎名孝明, 新井達也, 新井達也, 引田理英, 三尾和弘, 三浦裕, 黒須洋, 黒尾誠, et al. Dynamic X-ray Single Particle Observations of Calciprotein Particles. 量子ビームサイエンスフェスタ(Web). 2023. 2022

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Professional career (1)：

Association Membership(s) (4)：

THE BIOPHYSICAL SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , Biophysical Society , 日本顕微鏡学会

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