Rchr
J-GLOBAL ID：200901027386557032
Update date: Mar. 26, 2024
Matsui Toshitaka
マツイ トシタカ | Matsui Toshitaka
Affiliation and department：
Job title：
准教授
Homepage URL (2)：
http://www2.tagen.tohoku.ac.jp/lab/mizukami/
,
http://www2.tagen.tohoku.ac.jp/lab/mizukami/html/index.html
Research field (4)：
Inorganic and coordination chemistry
, Biochemistry
, Molecular biochemistry
, Functional biochemistry
Research keywords (5)：
heme catabolism
, enzyme
, reaction mechanism
, oxygen activation
, protein
Research theme for competitive and other funds (22)：
- 2022 - 2024 Functional regulation of MhuD-type heme degrading enzyme by siderophore
- 2020 - 2023 特殊ビリンの生体内検出とタンパク質ラベル化への応用
- 2020 - 2022 ケージド中間体を用いた2種のヘム分解酵素の機構解明
- 2015 - 2018 Critical essence hidden in two catabolic enzymes for biological pigments
- 2015 - 2017 歪みに感応するヘム分解機構とその精密制御
- 2013 - 2015 ゆがんだヘムの分解機構と触媒反応への応用
- 2012 - 2015 Compilation of heme oxygenase catalysis
- 2015 - 色素代謝酵素の特殊な機構と反応エッセンスの解明
- 2011 - 2013 Paradigm shift in enzymatic heme degradation
- 2009 - 2011 Reaction Mechanism of Heme Oxygenase
- 2008 - 2009 A novel heme catabolism : Reaction mechansim and detection from biological systems
- 2006 - 2007 Mechanism of porphyrin ring cleavage in the heme oxygenase catalysis
- 2006 - 2007 新たなヘム分解反応の分子機構
- 2004 - 2005 病原性細菌のヘムシャペロンと「トロイの木馬」型化合物
- 2004 - 2005 Roles of novel hydroperoxo-type active intermediates in the heme oxygenase catalysis
- 2001 - 2004 Construction of Environmental Biremediation Enzymes Whose Catalysis is Regulated by Light and Molecular Switches
- 2000 - 2004 NO-cGMP系情報伝達システムの分子機構
- 2002 - 2003 Following Heme Oxygenase Reaction at Atomic Scale
- 2002 - 2003 ヘムオキシゲナーゼによるヘム分解反応の全貌を明らかにする
- 2000 - 2001 Structure and Function of heme related proteins involved in intracellular signal transduction
- 1997 - 2000 TOXIN-DIRECTED MOLECULAR CONVERSION SYSTEM WITH YEAST HARBORING HIGHLY ACTIVATED P450 ENZYME BY ARTIFICIAL MUTAGENESIS
- 1998 - 1999 軸配位子によるヘム酸素の機能制御機構の解明
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Papers (78)：
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Takao Fujisawa, Satoshi Takenaka, Lila Maekawa, Toshiyuki Kowada, Toshitaka Matsui, Shin Mizukami, Isao Naguro, Hidenori Ichijo. Zinc controls histone acetyltransferase KAT7 activity to maintain cellular zinc homeostasis. 2023
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Toshitaka Matsui. Regulatory mechanism of formaldehyde release in heme degradation catalyzed by Staphylococcus aureus IsdG. Journal of Biological Chemistry. 2023. 299. 5. 104648-104648
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Himadri S. Sarkar, Takato Mashita, Toshiyuki Kowada, Satoshi Hamaguchi, Toshizo Sato, Kento Kasahara, Nobuyuki Matubayasi, Toshitaka Matsui, Shin Mizukami. Arylazopyrazole-Based Photoswitchable Inhibitors Selective for Escherichia coli Dihydrofolate Reductase. ACS Chemical Biology. 2023. 18. 2. 340-346
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Takato Mashita, Toshiyuki Kowada, Hayashi Yamamoto, Satoshi Hamaguchi, Toshitaka Matsui, Shin Mizukami. Quantitative and Repetitive Control of Subcellular Protein-Protein Interaction Using a Photochromic Dimerizer. ChemRxiv. 2022
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Mizuki Sawata, Hiroki Shima, Kazutaka Murayama, Toshitaka Matsui, Kazuhiko Igarashi, Kazumasa Funabashi, Kenji Ite, Kenji Kizawa, Hidenari Takahara, Masaki Unno. Autocitrullination and Changes in the Activity of Peptidylarginine Deiminase 3 Induced by High Ca2+ Concentrations. ACS Omega. 2022. 7. 32. 28378-28387
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MISC (23)：
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Toshitaka Matsui. Diverse molecular mechanism of heme catabolism. 2023. 59. 3. 196-200
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道順暢彦, 関根由可里, 松井敏高, 石森浩一郎, 石森浩一郎, 内田毅, 内田毅. 鉄キレート剤の添加によるコレラ菌由来ヘム分解酵素HutZの活性抑制機構. 東北大学多元物質科学研究所研究発表会講演予稿集. 2015. 15th
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渡部 美紀, 村山 和隆, 松井 敏高, 齋藤 正男, 五十嵐 和彦. ヘムによる天然変性タンパク質Bach2の制御. 日本生化学会大会プログラム・講演要旨集. 2014. 87回. [3P-341]
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Shusuke Nambu, Toshitaka Matsui, Celia W. Goulding, Kouhei Tsumoto, Satoshi Takahasi, Masao Ikeda-Saito. Paradigm shift in heme degradation; heme oxygenase and IsdG. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S717-S717
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M. Matsui, K. Igarashi, K. Murayama, T. Matsui, M. Ikeda-Saito, T. Matsumoto. Heme regulates unstructured region of transcription factor Bach2. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S243-S243
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Books (1)：
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ヘムタンパク質の科学: 生理機能の理解とその展開に向けて
エヌ・ティー・エス 2022 ISBN:4860437780
Lectures and oral presentations (120)：
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Mechanism of formaldehyde release in the heme degradation by IsdG from Staphylococcus aureus
(The 10th Asian Biological Inorganic Chemistry Conference (AsBIC10) 2022)
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Quantitative Mapping of Subcellular Labile Zn2+ Concentrations Using Localizable Small-Molecule Fluorescent Probes
(10th Asian Biological Inorganic Chemistry Conference (AsBIC10) 2022)
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Time-Lapse Ratiometric Imaging of Mitochondrial pH during Mitophagy Using a Localizable Fluorescent Probe
(10th Asian Biological Inorganic Chemistry Conference (AsBIC10) 2022)
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Development of photochromic ligands for quantitative and photo-reversible protein labeling
(2022)
-
酵素の Chemistry を解明して何が言えるだろうか?
(「生命金属科学」令和4年度夏の合宿 2022)
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Education (3)：
- 1995 - 1998 The Graduate University for Advanced Studies Graduate School, Division of Mathematical and Physical Science 構造分子科学専攻
- 1993 - 1995 京都大学大学院 工学研究科 分子工学専攻
- 1989 - 1993 Kyoto University Faculty of Engineering 石油化学科
Professional career (2)：
- 博士(理学) (The Graduate University for Advanced Studies)
- 修士(工学) (Kyoto University)
Work history (5)：
- 2013/11 - 2023/03 Tohoku University Institute of Multidisciplinary Research for Advanced Materials Associate Professor
- 2005/09 - 2013/10 Tohoku University Institute of Multidisciplinary Research for Advanced Materials Lecturer
- 2001/04 - 2005/08 Tohoku University Institute of Multidisciplinary Research for Advanced Materials Assistant Professor
- 2000/04 - 2001/03 Tohoku University Assistant Professor
- 1998/04 - 2000/03 JSPS (Institute for Molecular Science) Postdoctoral Fellow
Association Membership(s) (3)：
The Biophysical Society of Japan
, 日本生化学会
, 日本化学会
