Rchr
J-GLOBAL ID：200901027433281156
Update date: Nov. 16, 2024
Kobayashi Daiki
コバヤシ ダイキ | Kobayashi Daiki
Affiliation and department：
Research field (4)：
Pathobiochemistry
, Applied biochemistry
, Molecular biology
, Functional biochemistry
Research keywords (3)：
プロテオミクス
, 生化学
, 分子生物学
Research theme for competitive and other funds (11)：
- 2024 - 2025 Elucidation of intracellular and extracellular signals involved in abnormal neural differentiation and tumorigenesis in neurofibromatosis and development of therapeutic strategies
- 2022 - 2025 神経線維腫症の神経系細胞異常分化と腫瘍化の責任因子シグナルと治療標的の解明
- 2022 - 2025 プロテオーム熱安定性評価法(TPP)によるがん細胞の酸化ストレス耐性機構の解明
- 2020 - 2023 質量分析によるアミノ酸配列de novo決定のための新規手法開発
- 2019 - 2022 TCTP-EF1A2による翻訳制御を標的としたNF1腫瘍化機構の解析と治療法開発
- 2017 - 2022 Metabolic adaptation of type 2 diabetes
- 2016 - 2020 Identification and fuctional analysis of a novel molecular signal network related to NF1 tumorigenesis via the activation of translation mediated by TCTP
- 2013 - 2016 Analysis of the molecular mechanism and clinical targets for neural tumors via the loss of function of NF1/NF2 gene products
- 2014 - 2015 Elucidation of functional roles of a novel related protein, TCTP, in NF1 tumors
- 2012 - 2014 Elucidation of the pathogenic mechanism of, and construction of therapeutic strategy for, Neurofibromatosis type 1-associated tumors via TCTP
- 2007 - 2009 Analysis of cellular signal transduction via Neurofibromatosis tumor suppressor gene products and development of their clinical targets
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Papers (30)：
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Shujiro Okuda, Akiyasu C Yoshizawa, Daiki Kobayashi, Yushi Takahashi, Yu Watanabe, Yuki Moriya, Atsushi Hatano, Tomoyo Takami, Masaki Matsumoto, Norie Araki, et al. jPOST environment accelerates the reuse and reanalysis of public proteome mass spectrometry data. Nucleic Acids Research. 2024
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Yoshitomi Kanemitsu, Daiki Kobayashi, Kohta Nakatani, Yoshihiro Izumi, Takeshi Bamba, Masaki Matsumoto. Development and Application of LC-MS/MS Method for Determination of Major Metabolites Intra/Extra Cultured Cell Lines. Proteome Letters. 2024. 9. 1-11
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Akiko Niibori-Nambu, Yoshimune Yamasaki, Daiki Kobayashi, Kiyohiko Angata, Atsushi Kuno, Orasa Panawan, Atit Silsirivanit, Hisashi Narimatsu, Norie Araki. Chondroitin sulfate modification of CSPG4 regulates the maintenance and differentiation of glioma-initiating cells via integrin-associated signaling. Journal of Biological Chemistry. 2024. 300. 3. 105706-105706
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Takao Kitagawa, Daiki Kobayashi, Byron Baron, Hajime Okita, Tatsuo Miyamoto, Rie Takai, Durga Paudel, Tohru Ohta, Yoichi Asaoka, Masayuki Tokunaga, et al. AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing's sarcoma cells. PloS one. 2022. 17. 10. e0269077
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Eri Matsubara, Yoshihiro Komohara, Shigeyuki Esumi, Yusuke Shinchi, Shiho Ishizuka, Remi Mito, Cheng Pan, Hiromu Yano, Daiki Kobayashi, Yukio Fujiwara, et al. SPP1 Derived from Macrophages Is Associated with a Worse Clinical Course and Chemo-Resistance in Lung Adenocarcinoma. Cancers. 2022. 14. 18. 4374-4374
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MISC (86)：
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高橋悠志, 吉沢明康, 小林大樹, 守屋勇樹, 幡野敦, 高見知代, 松本雅記, 荒木令江, 田畑剛, 田畑剛, et al. Accelerating data re-analysis in jPOST using metadata from JPDM data papers. 日本プロテオーム学会大会プログラム・抄録集. 2024. 2024 (Web)
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Mukugi K, Kobayashi D, Tokuda T, Araki N. Elucidation of the interaction between NF1-associated factor TCTPand translation elongation factors by cross-linking MassSpectrometry (XL-MS). Abstracts for Annual Meeting of Japanese Proteomics Society. 2019. 2019. 200-200
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Norie Araki, Akiko Namubu Niibori, Daiki Kobayashi, Takuichiro Hide, Hideo Nakamura, Junichi Kuratsu. Integrated phospho-glyco-proteogenomics identified the potential clinical target signals against glioma stem cells. CANCER SCIENCE. 2018. 109. 656-656
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Norie Araki, Akiko N. Nambu, Atit Silsirivanit, Hiroki Okanishi, Daiki Kobayashi, Takuichiro Hide, Hideo Nakamura. Studies of key signals related to the maintenance and differentiation of glioma initiating cells by integrated-omics. CANCER SCIENCE. 2018. 109. 630-630
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荒木令江, 南部(新堀)晶子, 山崎義宗, 山ノ内祥訓, 當房浩一, 小林大樹. プロテオミクスを基盤としたプロテオゲノム情報の疾患研究への橋渡しとその応用. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st. ROMBUNNO.1PW1-02-4 (WEB ONLY)
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Lectures and oral presentations (1)：
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NGF刺激によるPC12細胞分化に関わる新規蛋白質のプロテオミクスによる同定とその役割
(BMB2008(第31回日本分子生物学会年会・第80回日本生化学会大会 合同大会) 2008)
Education (3)：
- 2003 - 2006 Kyushu University
- 2001 - 2003 Kyushu University
- 1997 - 2001 Kyushu University School of Agriculture
Professional career (1)：
Work history (4)：
- 2020/01 - 現在 新潟大学医歯学系 システム生化学分野 助教
- 2015/09 - 2019/12 Kumamoto University Faculty of Life Sciences
- 2010/01 - 2015/08 Kumamoto University Faculty of Life Sciences
- 2006/04 - 2009/12 熊本大学大学院医学薬学研究部 博士研究員
Committee career (3)：
- 2021/01 - 現在 Journal of Proteome Data and Methods, Editorial Broad Member
- 2021/01 - 現在 Proteome letters, 編集委員
- 2021/01 - 現在 日本プロテオーム学会 理事
Awards (2)：
- 令和2年度新潟大学優秀論文表彰
- 日本プロテオーム学会 2014年度日本プロテオーム学会奨励賞
Association Membership(s) (2)：
日本プロテオーム学会
, THE JAPANESE BIOCHEMICAL SOCIETY
