Ishikawa-Fujiwara Tomoko

フジワラトモコ | Ishikawa-Fujiwara Tomoko

Affiliation and department：

Research field (1)： Molecular biology

Research keywords (6)： carcingenesis , genome instability , mutagenesis , circadian rhythm , blue light , circadian rhythm

Research theme for competitive and other funds (13)：

2019 - 2022 Establishment of system for genomic mutation analysis using tissue stem cell in intestinal tumor
2018 - 2021 Establishment of stem cell competition analysis system utilizing somatic cell mosaicism
2015 - 2020 Mechnism of genome integrity maintenance in tissue stem cell
2013 - 2016 Elucidation of the role of chromatin structure on genome instability using genome editing technique
2013 - 2015 Establishing a transcriptional regulation system of the p21 gene by artificial transcription factors using genomic editing technique

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Papers (26)：

Takako Yasuda, Duolin Li, Erge Sha, Fumitaka Kakimoto, Hiroshi Mitani, Hiroshi Yamamoto, Tomoko Ishikawa-Fujiwara, Takeshi Todo, Shoji Oda. 3D reconstructed brain images reveal the possibility of the ogg1 gene to suppress the irradiation-induced apoptosis in embryonic brain in medaka (Oryzias latipes). Journal of radiation research. 2022
Yuji Nishiike, Daichi Miyazoe, Rie Togawa, Keiko Yokoyama, Kiyoshi Nakasone, Masayoshi Miyata, Yukiko Kikuchi, Yasuhiro Kamei, Takeshi Todo, Tomoko Ishikawa-Fujiwara, et al. Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka. Current biology : CB. 2021. 31. 8. 1699-1710
Yoshihiro Fujikawa, Tomoko Ishikawa-Fujiwara, Tony Kuo, Norio Shinkai, Tatsuma Shoji, Takashi Kawasaki, Yasuhiro Kamei, Yoshiyuki Sakuraba, Ayuko Sato, Masato Kinoshita, et al. Involvement of Rev1 in alkylating agent-induced loss of heterozygosity in Oryzias latipes. GENES TO CELLS. 2020. 25. 2. 124-138
藤川芳宏, 藤原智子, 佐藤鮎子, 志村勉, 児玉靖司, 辻村亨, 藤堂剛. 高発がんメダカ rev3l変異体を用いた腸管腫瘍の発がん解析(Rev3l-deficent medaka provides an excellent model for studies of intestinal tumor development). 日本放射線影響学会大会講演要旨集. 2019. 62回. 51-51
Yuma Terai, Ryuma Sato, Takahiro Yumiba, Ryuhei Harada, Kohei Shimizu, Tatsuya Toga, Tomoko Ishikawa-Fujiwara, Takeshi Todo, Shigenori Iwai, Yasuteru Shigeta, et al. Coulomb and CH-pi interactions in (6-4) photolyase-DNA complex dominate DNA binding and repair abilities. NUCLEIC ACIDS RESEARCH. 2018. 46. 13. 6761-6772

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MISC (37)：

藤川芳宏, 藤原智子, 佐藤鮎子, 佐久間哲史, 山本卓, 児玉靖司, 辻村亨, 藤堂剛. 年齢・組織依存的高発がんモデルメダカrev3l変異体. 日本放射線影響学会大会講演要旨集. 2018. 61回. 53-53
永田健斗, 保田隆子, 浅香智美, 舟山知夫, 鈴木芳代, 藤原智子, 藤堂剛, 尾田正二, 三谷啓志. メダカ精巣をモデルとした低線量率放射線被ばく影響の解析. 日本放射線影響学会大会講演要旨集. 2017. 60回. 112-112
藤川芳宏, 藤原智子, 佐藤鮎子, 佐久間哲史, 山本卓, 辻村亨, 藤堂剛. rev31変異体メダカの生殖組織および消化管腫瘍の解析. 日本放射線影響学会大会講演要旨集. 2017. 60回. 115-115
D. Yamada, H. M. Dokainish, T. Iwata, J. Yamamoto, T. Ishikawa, T. Todo, S. Iwai, E. D. Getzoff, K. Yura, A. Kitao, et al. Function conversion between CPD and (6-4) photolyases. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017. 46. S82-S82
D. Yamada, H. M. Dokainish, T. Iwata, J. Yamamoto, T. Ishikawa, T. Todo, S. Iwai, E. D. Getzoff, K. Yura, A. Kitao, et al. Function conversion between CPD and (6-4) photolyases. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017. 46. S276-S276

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Lectures and oral presentations (3)：

Characteristic gene expression pattern of highly tumorigenic medaka rev3l mutant
(2023)
高発がんメダカrev3l変異体のがんゲノム解析
(日本放射線影響学会第65回大会 2022)
Genome instability of tumor prone rev3l deficient medaka mutant
(2021)

Education (2)：

1997 - 2002 Kyoto University
1995 - 1997 Tokyo Medical and Dental University Faculty of Medicine School of Health Care Sciences

Professional career (1)：

Doctor(Human and enviromental studies) (京都大学)

Work history (9)：

2024/04 - 現在 Osaka University
2023/04 - 2024/03 Osaka University
2019/04 - 2023/03 Osaka University
2018/04 - 2019/03 Osaka University Graduate School of Medicine
2007/04 - 2018/03 Osaka University Graduate School of Medicine

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Association Membership(s) (1)：

Japan radiation research society

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