Kinashi Haruyasu

キナシハルヤス | Kinashi Haruyasu

Affiliation and department：

Research field (3)： Applied microbiology , Molecular biology , Bioorganic chemistry

Research keywords (2)：応用微生物学分子生物学天然物化学 , Applied Microbioloy Molecular Biology Natural Products Chemistry

Research theme for competitive and other funds (8)：

2006 - 2007 綿状プラスミドpSLA2-Lにコードされた二次代謝遺伝子群の機能解析とその応用
2004 - 2006 Diversity of the structures and functions of Streptomyces linear genomes
1997 - 1998 Studies on the structure and rearrangements of the linear chromosome of Streptomyces griseus 2247.
1991 - 1992 Genetic analysis of pleiotropic mutation independent of A factor derived from Streptomyces griseus
線状プラスミドpSLA2-L上にコードされた様々な二次代謝遺伝子群の機能解析

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Papers (80)：

Aiko Teshima, Hisashi Kondo, Yu Tanaka, Yosi Nindita, Yuya Misaki, Yuji Konaka, Yasuhiro Itakura, Tsugumi Tonokawa, Haruyasu Kinashi, Kenji Arakawa. Substrate specificity of two cytochrome P450 monooxygenases involved in lankamycin biosynthesis. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY. 2021. 85. 1. 115-125
Yuya Misaki, Shouji Yamamoto, Toshihiro Suzuki, Miyuki Iwakuni, Hiroaki Sasaki, Yuzuru Takahashi, Kuninobu Inada, Haruyasu Kinashi, Kenji Arakawa. SrrB, a Pseudo-Receptor Protein, Acts as a Negative Regulator for Lankacidin and Lankamycin Production in Streptomyces rochei. Frontiers in microbiology. 2020. 11. 1089-1089
Yosi Nindita, Zhisheng Cao, Amirudin Akhmad Fauzi, Yuya Misaki, Rukman Muslimin, Yingjie Yang, Yuh Shiwa, Hirofumi Yoshikawa, Michihira Tagami, Alexander Lezhava, et al. The genome sequence of Streptomyces rochei 7434AN4, which carries a linear chromosome and three characteristic linear plasmids. Scientific Reports. 2019. 9. 1. 10973-1-10973-11
Yusuke Yamauchi, Yosi Nindita, Keisuke Hara, Asako Umeshiro, Yu Yabuuchi, Toshihiro Suzuki, Haruyasu Kinashi, Kenji Arakawa. Quinoprotein dehydrogenase functions at the final oxidation step of lankacidin biosynthesis in Streptomyces rochei 7434AN4. Journal of Bioscience and Bioengineering. 2018. 126. 2. 145-152
Kunitake, Hirofumi, Hiramatsu, Takahiro, Kinashi, Haruyasu, Arakawa, Kenji. Isolation and Biosynthesis of an Azoxyalkene Compound Produced by a Multiple Gene Disruptant of Streptomyces rochei. CHEMBIOCHEM. 2015. 16. 15. 2237-2243

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MISC (24)：

木梨陽康. 放線菌の化学と生物学. 化学と生物. 2018. 11. 707-707
Biosynthetic investigation and biological activity of azoxyalkene compound KA57-A generated by multiple mutations on secondary metabolite and regulatory genes. 2017. 59. 657-662
波多江希, 津田直人, 木梨陽康, 荒川賢治. 放線菌Streptomyces rocheiの抗生物質生産を誘導するシグナル分子SRBの単離・構造決定および生合成. 第58回天然有機化合物討論会講演要旨集. 2016. 575-580
Arakawa Kenji, Kinashi Haruyasu. 2S-Dp01 Analysis and application of the Streptomyces regulatory network for secondary metabolites. 2013. 65. 92-92
荒川賢治, 木梨陽康. 線状プラスミド上の抗生物質生合成クラスターの解析とその応用. バイオサイエンスとインダストリー. 2008. 66. 504-508

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Patents (3)：

新抗生物質サリノマイシンAIIの製法
新抗生物質SY-1物質の製法
植物生長調節剤

Books (7)：

Streptomyces linear plasmids: their discovery, functions, interactions with other replicons and evolutionary significance. Microbiology Monographs, Vol 7, ed. by F Meinhardt, R Klassen, pp. 1-31.
Springer, Berlin/Heidelberg 2007
抗生物質を作る細菌、放線菌の線状プラスミドと線状染色体. バイオテクノロジー講義 pp. 42-49.
朝倉書店 1999
放線菌の線状ゲノム(染色体・プラスミド)の構造と機能の解析. 工学部シリーズ-広島大学工学部 pp. 172-173.
三田出版会 1997
放線菌-抗生物質を作る微生物-. 技術最前線82話-21世紀の技術社会を拓く pp. 98-99.
広島大学工学部 1996
Pulsed field gel electrophoresis: Isolation and analysis of large linear plasmids. Methods in Gene Technology. Vol 2, ed. by JW Dale, PG Sanders, pp. 227-240.
JAI Press, London 1994

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Works (7)：

放線菌の環状プラスミドpSV1と線状プラスミドSCP1の比較解析
2003 -
放線菌の線状プラスミドSCP1と線状染色体の相互作用の解析
1994 - 2001
Streptomyces coelicolorの挿入配列IS466の解析
2000 -
Streptomyces griseusのafsA遺伝子の位置づけ
1997 -
放線菌Streptomyces coelicolor A3(2)染色体の遺伝子及びコスミド地図の作製
1994 - 1996

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Education (3)：

1969 - 1974 The University of Tokyo
1966 - 1969 The University of Tokyo
1965 - 1969 The University of Tokyo Faculty of Agriculture

Professional career (2)：

農学博士 (東京大学)
農学修士 (東京大学)

Work history (10)：

2017 - 現在日本農芸化学会有功会員
2017 - 現在日本放線菌学会終身会員
2010 - 現在 Hiroshima University
2010 - 2011 広島大学大学院先端物質科学研究科分子生命機能科学専攻非常勤講師
1998 - 2010 Hiroshima University Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter

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Awards (1)：

2007 - 日本放線菌学会日本放線菌学会学会賞放線菌の線状ゲノムの発見とその構造・機能および進化に関する総括的研究

Association Membership(s) (2)：

日本放線菌学会 , 日本農芸化学会

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