Rchr
J-GLOBAL ID：200901028527841119
Update date: Apr. 22, 2024
Kojima Masaki
コジマ マサキ | Kojima Masaki
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://www.ls.toyaku.ac.jp/~bioinfo
Research field (2)：
Biological, health, and medical informatics
, Biophysics
Research keywords (3)：
in silico 創薬
, Bioinformatics
, Small-Angle X-ray Scattering
Research theme for competitive and other funds (23)：
- 2017 - 2020 健康社会の実現に向けた創薬化学の展開と人財育成
- 2015 - 2017 核・ミトコンドリア遺伝子の網羅的トランスゲノム解析による心不全重症化機構の解明
- 2012 - 2017 タンパク質の複合体構造・相互作用に関する総合的な予測・解析の実施と高度化
- 2015 - 2016 Development of highly specific oncolytic herpes virus vectors by modification of two envelope glycoproteins
- 2011 - 2011 アミロイド化初期段階におけるドパミンによるオリゴマー形式の高精度検出法の開発
- 2009 - 2011 Elucidation of structure and function relationship in multiple-domain chitinases probed by a combination of X-ray crystallography, solution scattering, and molecular dynamics simulation
- 2008 - 2010 Studies of an early stage amyloid formation for Parkinson`s Disease casual protein.
- 2005 - 2007 Development of high precision method to detect amyloid formation for Alzheimer's disease
- 2001 - 2002 フォールディング機構に基づくHIVプロテアーゼの不活性化
- 1999 - 2001 Molecular Biological Studies on the Proteases and .Their Inhibifors of Filarial Parasites
- 2000 - 2000 バイオターゲティング素子としての抗体断片の高効率生産と構造機能解析
- 1999 - 2000 Post-genome study on filarial proteases for development of inhibitors.
- 1997 - 2000 A systematic analysis of the effects of fine-structures of antibodies on microbial expression and secretion and construction of a general-purpose system for antibody production.
- 1999 - 1999 バイオターゲティング素子としての抗体断片の高効率生産と構造機能解析
- 1998 - 1998 チオレドキシン類似インタエレメント酵素群の構造機能相関と分子進化
- 1998 - 1998 バイオターゲッティング素子としての抗体断片の高効率生産と構造機能解析
- 1997 - 1998 Structural, Functional and Physiological Characterization of Novel Brain-Gut Proteinases
- 1996 - 1998 Studies on Filarial Proteinases and Their Inhibitors for Development of Filarial Drugs
- 1997 - 1997 チオレドキシン類似インタエレメント酵素群の構造機能相関と分子進化
- 1996 - 1996 環境汚染物質の除去を目的としたハロゲン化炭素水素代謝酵素の蛋白工学的研究
- 1996 - 1996 立体構造と蛋白工学的解析に基づくグルタチオン・トランスフェラーゼの機能発現機構
- 1996 - 1996 リボヌクレアーゼT_1の構造・機能相関の物理化学的解析
- 1995 - 1996 Systematic search for novel proteinases in gastrointestinal tract and studies on their physiological roles and structure/function
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Papers (68)：
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Shinpei Ohnuki, Shinichi Tokishita, Masaki Kojima, Shoko Fujiwara. Effect of chlorpyrifos-exposure on the expression levels of CYP genes in Daphnia magna and examination of a possibility that an up-regulated clan 3 CYP, CYP360A8, reacts with pesticides. Environmental Toxicology. 2024. 1-13
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Current Status and Issues of Machine Translation. New Method Proposed for English-Japanese Translation. The Bulletin of Tokyo University of Pharmacy and Life Sciences. 2024. 27. 23-28
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Ken-ichi Fujita, Misa Ito, Midori Irie, Kotaro Harada, Naoko Fujiwara, Yuya Ikeda, Hanae Yoshioka, Tomohiro Yamazaki, Masaki Kojima, Bunzo Mikami, et al. Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes. Nature Communications. 2024. 15. 1. 455
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Zen Kouchi, Masaki Kojima. A Structural Network Analysis of Neuronal ArhGAP21/23 Interactors by Computational Modeling. ACS Omega. 2023. 8. 22. 19249-19264
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Zen Kouchi, Masaki Kojima. Function of SYDE C2-RhoGAP family as signaling hubs for neuronal development deduced by computational analysis. Scientific Reports. 2022. 12. 1. 4325
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MISC (33)：
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Masaki Kojima, Yoshitaka Matsumura. Data Analyses for Protein Unfolding Based on Thermodynamics. The Bulletin of Tokyo University of Pharmacy and Life Sciences. 2023. 26. 74-78
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Eimi Aoyagi, Masaki Kojima. Tree representation of protein conformation and estimation of EC number based on GCN. 2022
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青柳詠美, 小島正樹. アクセント単位形の推測を用いた日本語複合語のアクセント句の合成. 言語処理学会 第28回年次大会 発表論文集. 2022. 1012-1017
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Masaki Kojima, Miho Ishizuka. Nonlinear Least-squares Application by Downhill Simplex Method. The Bulletin of Tokyo University of Pharmacy and Life Sciences. 2022. 25. 116-120
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松村 義隆, 井上 広大, 墨野倉 誠, 久保 美香子, 出村 茉莉子, 市岡 隆幸, 森本 康幹, 田代 充, 石橋 健一, 大野 尚仁, et al. 物理化学的手法と分子動力学シミュレーションによるアガリクス由来βグルカンの立体構造観測. バイオイメージング. 2021. 30. 2. 59-59
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Books (9)：
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改訂版 理系研究者のためのアカデミックライティング
東京図書 2023 ISBN:9784489024092
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薬学のための統計教科書
東京図書 2015 ISBN:9784489022036
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Drug Design -Structure- and ligand-based approaches
2014 ISBN:9784807908493
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化学・生命科学のための線形代数
東京化学同人 2012 ISBN:9784807907977
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Science Research Writing For Non-Native Speakers of English
2011 ISBN:9784489021183
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Education (3)：
- 1990 - 1995 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
- 1988 - 1990 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
- 1986 - 1988 The University of Tokyo Junior Division Natural Sciences I
Professional career (1)：
Work history (6)：
- 2009/01 - 現在 Tokyo University of Pharmacy and Life Sciences School of Life Sciences Professor
- 2007/04 - 2008/12 Iwate Medical University School of Pharmacy Associate Professor
- 2006/04 - 2007/03 Tokyo University of Pharmacy and Life Sciences School of Life Sciences Associate Professor
- 2005/09 - 2006/03 Tokyo University of Pharmacy and Life Sciences School of Life Sciences Associate Professor/Lecturer
- 1995/04 - 2005/08 Tokyo University of Pharmacy and Life Sciences School of Life Sciences Assistant Professor
- 1992/04 - 1995/03 Japan Society for the Promotion of Science Research Fellowship for Young Scientists
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Committee career (3)：
- 2015/01 - 現在 日本バイオイメージング学会 欧文誌編集委員長
- 2000 - 現在 日本バイオイメージング学会 評議員
- 2017 - 2017 日本バイオイメージング学会 第26回学術集会大会長
Awards (1)：
Association Membership(s) (2)：
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