Rchr
J-GLOBAL ID:200901028778360314
Update date: Jul. 17, 2024
Murakami Tomohiko
ムラカミ トモヒコ | Murakami Tomohiko
Affiliation and department:
Job title:
Associate Professor
Research field (2):
Oral medicine (pathology)
, Pathobiochemistry
Research theme for competitive and other funds (14):
- 2023 - 2027 炎症性ドライバーIκBζの相反性の理解から挑む自己免疫疾患の発症機序の解明と応用
- 2022 - 2025 慢性炎症と小胞体ストレスの連関機序と病態への関与
- 2021 - 2024 転写プラットフォーム因子Zfhxファミリーによる骨格形成の時空間的制御機構の解明
- 2020 - 2023 骨・軟骨破壊性疾患の分子標的治療薬の創薬基盤構築を目指す骨免疫学の新機軸の創出
- 2019 - 2022 Analysis of crosstalk mechanisms of cellular responses in chronic diseases
- 2016 - 2021 Development of innovative medical technology based on integrated understanding of both protection and destruction of articular cartilage homeostasis.
- 2018 - 2020 Measurement of ER stress without destruction
- 2016 - 2019 Regulatory mechanism of NLRP3 inflammasome in chronic inflammation
- 2016 - 2018 Establishment of system for predicting inflammatory diseases
- 2016 - 2018 Investigation of transcriptional network system of chondrocytes by novel gene-editing cloning technique
- 2014 - 2016 Search of the cell type-specific inflammatory response
- 2014 - 2016 Development of screening system for bone forming reagents by using TALEN genome engineering technique
- 2008 - 2010 Analysis of a membrane bound transcription factor OASIS in osteogenesis
- 2008 - 2009 小胞体品質管理機構による骨形成制御の解析
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Papers (44):
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Sachi Ichiyama-Kobayashi, Kenji Hata, Kanta Wakamori, Yoshifumi Takahata, Tomohiko Murakami, Hitomi Yamanaka, Hiroshi Takano, Ryoji Yao, Narikazu Uzawa, Riko Nishimura. Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development. JCI insight. 2024. 9. 11
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Tomohiko Murakami, Lerdluck Ruengsinpinya, Yoshifumi Takahata, Yuri Nakaminami, Kenji Hata, Riko Nishimura. HOXA10 promotes Gdf5 expression in articular chondrocytes. Scientific reports. 2023. 13. 1. 22778-22778
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Tomohiko Murakami, Yoshifumi Takahata, Kenji Hata, Kosuke Ebina, Katsutoshi Hirose, Lerdluck Ruengsinpinya, Yuri Nakaminami, Yuki Etani, Sachi Kobayashi, Takashi Maruyama, et al. Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes. Science Signaling. 2022. 15. 758. eabl5304
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Hiroko Yagi, Yoshifumi Takahata, Tomohiko Murakami, Yuri Nakaminami, Hiromasa Hagino, Shiori Yamamoto, Shinya Murakami, Kenji Hata, Riko Nishimura. Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx2. Journal of bone and mineral metabolism. 2022
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Tomohiko Murakami, Yuri Nakaminami, Yoshifumi Takahata, Kenji Hata, Riko Nishimura. Activation and Function of NLRP3 Inflammasome in Bone and Joint-Related Diseases. International journal of molecular sciences. 2022. 23. 10
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MISC (48):
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村上智彦, 高畑佳史, 波多賢二, 中南友里, 西村理行. 骨軟骨形成におけるGタンパク質サブユニットβ1の機能解析. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2022. 40th
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波多賢二, 高畑佳史, 村上智彦, 西村理行, 米田俊之. 乳酸受容体GPR81は骨における乳がん細胞の増殖を制御する. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2022. 40th
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小林紗知, 小林紗知, 波多賢二, 高畑佳史, 村上智彦, 西村理行. 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2021. 39th
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ルゥァンシンピンヤー ルードラック, 中村恵理子, 高畑佳史, 波多賢二, 中南友里, 西村理行, 村上智彦. GNB1(G protein subunit β1)is required for the late stage of endochondral ossification. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2020. 38th
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高畑佳史, 中村恵理子, 萩野弘将, 村上智彦, 波多賢二, 西村理行. 転写因子Runx2の新規標的遺伝子Smoc1,Smoc2による骨形成制御機構の解明. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2020. 38th
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Awards (9):
- 2024 - 日本軟骨代謝学会賞
- 2024 - 大阪大学弓倉学術賞
- 2016 - 日本骨代謝学会 研究奨励賞
- 2015 - 大阪大学総長奨励賞
- 2015 - 大阪大学歯学研究科研究科長賞
- 2013 - Keystone Symposia Scholarship, Metabolic Control of Inflammation and Immunity
- 2010 - 宇部興産学術振興財団 学術奨励賞
- 2009 - 日本骨代謝学会 優秀演題賞
- 2007 - Plenary Poster Award, American Society for Bone and Mineral Research Meeting
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