Rchr
J-GLOBAL ID:200901028785668120
Update date: Sep. 19, 2024
ADACHI TAKAHIRO
アダチ タカヒロ | ADACHI TAKAHIRO
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Research field (6):
Applied biochemistry
, Conservation science (plants)
, Molecular biology
, Functional biochemistry
, Applied biofunctional and bioprocess engineering
, Polymer materials
Research keywords (10):
タンパク質生産
, 血球
, 基底膜
, ゼラチン
, コラーゲン
, 遺伝子組換え
, カイコ
, molecular biology
, biochemistry
, biotechnology
Research theme for competitive and other funds (6):
2007 - 2010 ヒト型ゼラチンを合成する遺伝子組換えカイコの作出
1998 - 2010 遺伝子組み換えカイコを利用したタンパク質生産
1998 - 2009 Synthesis of human collagen in silkworms, Bombyx mori
1998 - 2006 カイコ血球において合成されるIV型コラーゲンに関する研究
1995 - 1997 海産生物ホヤにおけるバナジウム濃縮に関連する研究
Involvement of type IV collagen in self-defense reaction and metamorphosis in insects
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Papers (9):
Takashi Kitajima, Sei Obuse, Takahiro Adachi, Masahiro Tomita, Yoshihiro Ito. Recombinant Human Gelatin Substitute With Photoreactive Properties for Cell Culture and Tissue Engineering. BIOTECHNOLOGY AND BIOENGINEERING. 2011. 108. 10. 2468-2476
Shinya Urano, Chinatsu Kaneko, Takahito Nei, Natsuki Motoi, Ryushi Tazawa, Masato Watanabe, Masahiro Tomita, Takahiro Adachi, Hiroko Kanazawa, Koh Nakata. A cell-free assay to estimate the neutralizing capacity of granulocyte-macrophage colony-stimulating factor autoantibodies. JOURNAL OF IMMUNOLOGICAL METHODS. 2010. 360. 1-2. 141-148
Takahiro Adachi, Xiaobiao Wang, Tomoko Murata, Masanobu Obara, Hidenori Akutsu, Masakazu Machida, Akirihiro Umezawa, Masahiro Tomita. Production of a Non-Triple Helical Collagen alpha Chain in Transgenic Silkworms and Its Evaluation as a Gelatin Substitute for Cell Culture. BIOTECHNOLOGY AND BIOENGINEERING. 2010. 106. 6. 860-870
Masahiro Tomita, Rika Hino, Shingo Ogawa, Masashi Iizuka, Takahiro Adachi, Katsuhiko Shimizu, Hisaya Sotoshiro, Katsutoshi Yoshizato. A germline transgenic silkworm that secretes recombinant proteins in the sericin layer of cocoon. TRANSGENIC RESEARCH. 2007. 16. 4. 449-465
Katsuhiko Shimizu, Shingo Ogawa, Rika Hino, Takahiro Adachi, Masahiro Tomita, Katsutoshi Yoshizato. Structure and function of 5 '-flanking regions of Bombyx mori fibroin heavy chain gene: Identification of a novel transcription enhancing element with a homeodomain protein-binding motif. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2007. 37. 7. 713-725
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MISC (6):
Katsuhiko Shimizu, Shingo Ogawa, Rika Hino, Takahiro Adachi, Masahiro Tomita, Katsutoshi Yoshizato. Structure and function of 5 '-flanking regions of Bombyx mori fibroin heavy chain gene: Identification of a novel transcription enhancing element with a homeodomain protein-binding motif. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2007. 37. 7. 713-725
Tomita M, Hino R, Ogawa S, Iizuka M, Adachi T, Shimizu K, Sotoshiro H, Yoshizato K. A germline transgenic silkworm that secretes recombinant proteins in the sericin layer of cocoon. Transgenic Res. 2007, 16, 449-65. Transgenic Res. 2007. 16. 449-65.
Takahiro Adachi, Masahiro Tomita, Katsuhiko Shimizu, Shingo Ogawa, Katsutoshi Yoshizato. Generation of hybrid transgenic silkworms that express Bombyx mori prolyl-hydroxylase alpha-subunits and human collagens in posterior silk glands: Production of cocoons that contained collagens with hydroxylated proline residues. JOURNAL OF BIOTECHNOLOGY. 2006. 126. 2. 205-219
T Adachi, M Tomita, K Yoshizato. Synthesis of prolyl 4-hydroxylase ot subunit and type IV collagen in hemocytic granular cells of silkworm, Bombyx mori: Involvement of type IV collagen in self-defense reaction and metamorphosis. MATRIX BIOLOGY. 2005. 24. 2. 136-154
T Ueki, T Adachi, S Kawano, M Aoshima, N Yamaguchi, K Kanamori, H Michibata. Vanadium-binding proteins (vanabins) from a vanadium-rich ascidian Ascidia sydneiensis samea. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. 2003. 1626. 1-3. 43-50
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Patents (1):
ヒト・コラーゲンを産生する形質転換カイコ
Books (1):
コラーゲンの製造と応用展開
シーエムシー出版 ISBN:9784781300719
Lectures and oral presentations (16):
Recombinant aipha1 chain of human type I collagen in the silkworms Bombyx mori: production of human gelatin as a novel biomaterial
(Yokosuka Science Festa 2009 2009)
カイコによって生産されたヒト型ゼラチンの細胞生物学的評価
(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 2008)
遺伝子組換えカイコを用いたヒトI型コラーゲンα1鎖の産生
(第30回日本分子生物学会年会・第80回日本生化学会大会 2007)
遺伝子組換えカイコを用いたヒトI型コラーゲンalpha1鎖の産生
(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会 2007)
FKBP65によるプロリン水酸化ヒトコラーゲンのカイコ絹糸腺への効果的な分泌
(日本分子生物学会2006フォーラム(名古屋) 2006)
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Education (5):
- 2002 Hiroshima University
- 2002 Hiroshima University Doctor course
- 1998 Hiroshima University Master course
- 1996 Hiroshima University Faculty of Science
- 1996 Hiroshima University Faculty of Science
Professional career (1):
Doctor of science (Hiroshima University)
Association Membership(s) (4):
マトリックス研究会
, 日本再生医療学会
, 日本分子生物学会
, The Molecular Biology Society of Japan
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