Rchr
J-GLOBAL ID:200901028976992938
Update date: Sep. 01, 2024
Tsujiuchi Toshifumi
ツジウチ トシフミ | Tsujiuchi Toshifumi
Affiliation and department:
Job title:
Professor
Research field (2):
Experimental pathology
, Human pathology
Research keywords (5):
oncology
, cancer biology
, cell signaling
, 分子病理学
, molecular pathology
Research theme for competitive and other funds (12):
- 2021 - 2024 LPA受容体シグナルを介するがん細胞の抗がん剤・放射線感受性調節機構の解明
- 2018 - 2021 Roles of LPA receptors in the acquisition of malignant properties in cancer cells treated with anticancer drugs
- 2015 - 2020 Translational applications of broad spectrum natural compounds and phytochemicals or their derivatives to the novel treatment strategy against sarcomas
- 2012 - 2015 Functional analysis of LPA receptors in the acquisition of malignant properties in cancer cells.
- 2012 - 2015 Abnormal LPA receptor signaling in cancer
- 2009 - 2011 Molecular mechanisms for LPA_3-mediated neurite branch formation
- 2008 - 2010 Isolation of cancer stem cells in bone and soft tissue tumors and novel molecular and cellular targeting therapy
- 1996 - 1999 Basic Research on the Development and Progression of Pancreatic Duct Adenocarcinoma
- 1995 - 1995 抗脂肪肝因子欠乏食によるラット肝発癌機構へのアラキドン酸カスケードの関与機構解析
- 1994 - 1994 抗脂肪肝因子欠乏食によるラット肝発癌機構へのアラキドン酸カスケードの関与機構解析
- 化学発癌機構の解析
- analysis of mechanism of carcinogenesis by chemical carcinogen
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Papers (261):
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Yamamoto M, Takai M, Yashiro N, Taniguchi A, Tamura M, Kusumoto Y, Nagano S, Tsujiuchi T. The role of LPA receptor signaling in modulating cellular responses of colon cancer cells co-cultured with lymphoid endothelial cells under hypoxic stress. Tissue and Cell. 2024. 91. 102528
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Takai M, Yamamoto M, Yashiro N, Nagano S, Kusumoto Y, Tamura M, Taniguchi A, Tsujiuchi T. Impact of cellular ATP levels on cell viability in response to fluorouracil through lysophosphatidic acid (LPA) receptor-4 (LPA4) and LPA6 in colon cancer cells. Adv Biol Regul. 2024. 93. 101042
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Takai M, Yamamoto M, Yashiro N, Tamura M, Taniguchi A, Nagano S, Kusumoto Y, Tsujiuchi T. FFAR-mediated signaling drives migration of pancreatic cancer cells in hypoxic fibroblast co-cultures. Biochem Biophys Res Commun. 2024. 727. 150322
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Takai M, Yamamoto M, Yashiro N, Tsujiuchi T. Involvement of lysophosphatidic acid (LPA) receptor-mediated signaling in breast cancer cell functions by long-term tamoxifen treatment under hypoxic and estrogen-deprived conditions. Pathol Res Pract. 2024. 260. 155385
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Takai M, Mori S, Honoki K, Tsujiuchi T. Roles of lysophosphatidic acid (LPA) receptor-mediated signaling in cancer cell biology. J Bioenerg Biomembr. 2024. 56. 475.-482
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MISC (33):
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岸 真五, 朴木 寛弥, 森 汐莉, 塚本 真治, 近藤 裕美子, 藤井 宏真, 城戸 顕, 谷 里奈, 西口 由希子, 笹平 智則, et al. プテロスティルベンはF0-F1ATPシンターゼ阻害を介して骨肉腫の幹細胞性を抑制しドキソルビシンの効果を増強させる. 日本整形外科学会雑誌. 2018. 92. 6. S1461-S1461
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田村和朗, 長尾哲二, 南武志, 日高雄二, 辻内俊文, 巽純子, 福嶋伸之, 加川尚, 西郷和真, 島本茂, et al. がんゲノム医療時代の遺伝カウンセラーの養成:文部科学省がんプロ養成プランへの参画. 日本人類遺伝学会大会プログラム・抄録集. 2018. 63rd. 380
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岸 真五, 朴木 寛弥, 国安 弘基, 城戸 顕, 藤井 宏真, 塚本 真治, 近藤 裕美子, 羅 奕, 門地 優衣, 森 汐莉, et al. Pterostilbeneは骨肉腫の増殖能およびスフェア形成能を抑制しドキソルビシンの効果を増強する. 日本整形外科学会雑誌. 2017. 91. 6. S1391-S1391
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Kanya Honoki, Hiromasa Fujii, Akira Kido, Shinji Tsukamoto, Toshio Mori, Yasuhito Tanaka, Toshifumi Tsujiuchi. Possible involvement of senescence bypass in mesenchymal stem cells for sarcomagenesis identified through a comparative gene expression profiling in rat sarcoma model. CANCER RESEARCH. 2015. 75
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Kanya Honoki, Toshifumi Tsujiuchi. Senescence bypass in mesenchymal stem cells: apotential pathogenesis and implications of pro-senescence therapy in sarcomas. EXPERT REVIEW OF ANTICANCER THERAPY. 2013. 13. 8. 983-996
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Books (2):
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ミネルヴァ書房, 『ケアマネジメント用語辞典(改訂版)』
2007
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ミネルヴァ書房, 『ケアマネジメント用語辞典』
2005
Lectures and oral presentations (3):
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膵炎関連痛モデルにおけるメシル酸カモスタットの抗侵害受容的作用.
(第79回日本薬理学会年会 2010)
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Involvement of endogenous hydrogen sulfide in acute pancreatitis-related pain.
(6th FENS Forum of European Neuroscience 2008)
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Hydrogen sulfide as a nociceptive messenger in rat and mouse pancreata.
(Neuroscience 2007 2007)
Education (2):
- - 1992 Nara Medical University
- - 1992 Nara Medical University Graduate School, Division of Medicine
Professional career (1):
Committee career (1):
Awards (1):
- 2006/03 - がん研究振興財団 第39回がん研究助成金
Association Membership(s) (2):
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