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J-GLOBAL ID：200901029158740903   Update date: Nov. 04, 2024

Ito Akihiko

イトウ アキヒコ | Ito Akihiko
Affiliation and department：
Kindai University Faculty of Medicine Department of Medicine

About Kindai University Faculty of Medicine Department of Medicine


Job title： Associate Professor
Research field  (1)： Experimental pathology
Research keywords  (2)： 癌転移の分子機構 ,  Molecular Basis of Metastasis
Research theme for competitive and other funds  (38)：
  • 2021 - 2025 食道癌術前化学療法の治療効果予測-低酸素イメージングと癌シグナル伝達因子との相関
  • 2021 - 2024 接着分子内在化を機序とする抗体創薬の基礎研究
  • 2022 - 2024 脳腫瘍を標的とする抗体薬物複合体の開発
  • 2019 - 2022 Immune related gene-expression profiling for the combination of chemotherapy and PD-1/PD-L1 inhibition.
  • 2018 - 2021 Analysis of tissue degeneration by internal pressure elevation
Show all
Papers (293)：
  • Fuka Takeuchi, Man Hagiyama, Azusa Yoneshige, Akihiro Wada, Takao Inoue, Yoichiroh Hosokawa, Akihiko Ito. Relief of pain in mice by an antibody with high affinity for cell adhesion molecule 1 on nerves. Life sciences. 2024. 357. 122997-122997
  • Makoto Yoshida, Jiayin Yuan, Takako Kihara, Neinei Kimura, Takashi Yamasaki, Mizuka Ohkouchi, Yuka Hashikura, Koji Isozaki, Man Hagiyama, Akihiko Ito, et al. Anti-tumor effect of antibody-drug conjugate targeting cell adhesion molecule 1 on GIST cells representing small intestinal GIST. Experimental and molecular pathology. 2024. 139. 104922-104922
  • Man Hagiyama, Azusa Yoneshige, Akihiro Wada, Ryuichiro Kimura, Shinji Ito, Takao Inoue, Fuka Takeuchi, Akihiko Ito. Efficient intracellular drug delivery by co-administration of two antibodies against cell adhesion molecule 1. Journal of controlled release : official journal of the Controlled Release Society. 2024. 371. 603-618
  • Hiroaki Kanemura, Toshihide Yokoyama, Ryu Nakajima, Atsushi Nakamura, Hiroaki Kuroda, Yoshitaka Kitamura, Hiroyasu Shoda, Nobuaki Mamesaya, Yoshihiro Miyata, Tatsuro Okamoto, et al. The Tumor Immune Microenvironment Is Associated With Recurrence in Early-Stage Lung Adenocarcinoma. JTO clinical and research reports. 2024. 5. 4. 100658-100658
  • Koji Haratani, Atsushi Nakamura, Nobuaki Mamesaya, Kenji Sawa, Yoshimasa Shiraishi, Ryota Saito, Junko Tanizaki, Yosuke Tamura, Akito Hata, Kosuke Tsuruno, et al. Association of immune-related adverse events with durvalumab efficacy after chemoradiotherapy in patients with unresectable Stage III non-small cell lung cancer. British journal of cancer. 2024
ｍore...
MISC (161)：
  • 井上敬夫, 金澤佑治, 水口信行, 前西修, 木村雅友, 木村雅友, 萩山満, 米重あづさ, 和田昭裕, 佐藤隆夫, et al. Ribosomal protein S6のリン酸化抑制がSHRSPにおける廃用性筋萎縮からの回復遅延に関係する. 高血圧関連疾患モデル学会学術総会抄録集. 2023. 59th (CD-ROM)
  • 武内風香, 萩山満, 菅野亜紀, 高岡裕, 佐々木健郎, 伊藤彰彦. Indigo Plant Leaf Extract Inhibits SARS-CoV-2 Spike Binding to Angiotensin-Converting Enzyme 2. 日本病理学会会誌. 2022. 111. 1
  • 萩山満, 米重あづさ, 武内風香, 伊藤彰彦. Adhesion molecule CADM1 contributes to proliferation of endometrial glandular cells. 日本病理学会会誌. 2022. 111. 1
  • 萩山 満, 米重 あづさ, 伊藤 彰彦. 上皮単層における細胞生存への寄与 接着分子CADM1. 日本病理学会会誌. 2021. 110. 1. 247-247
  • 大谷 知之, 村上 幸祐, 木村 雅友, 松木 充, 佐藤 隆夫, 松村 謙臣, 伊藤 彰彦. 子宮留膿腫に関連して生じた内膜偽リンパ腫. 日本病理学会会誌. 2021. 110. 1. 338-338
ｍore...
Books (6)：
  • Highlights in Cell Adhesion and Migration.
    Frontiers Media SA 2022
  • Linking experimental pathology experts in designing in vitro models of pathological conditions with researchers investigating molecular mechanisms of pathogenesis
    2019
  • Cell Adhesion and Migration in the Development of Multicellular Organisms.
    2019
  • はじめの一歩のイラスト病理学
    羊土社 2012
  • Alzheimer's disease pathogenesis-core concepts, shifting paradigms and therapeutic targets, Expression and cerebral function of amyloid precursor protein after rat traumatic brain injury
    Intech open access publisher 2011
ｍore...
Lectures and oral presentations  (132)：
  • がん微小環境特異的な組織滞在型(レジデント)メモリー様CD8T細胞の分化機構
    (第28回日本がん免疫学会総会・第37回日本バイオセラピィ学会学術集会総会 合同大会 2024)
  • Novel mechanism for primary aldosteronism:Gap junction failure caused by CADM1 mutations
    (2024)
  • A nove case of newly defined differentiated high-grade thyroid carcinoma(DHGTC)
    (2024)
  • Cancer Cytological Diagnosis by Analyzing Pathological Specimen Light Scattering Spectra with Machine Learning
    (2024)
  • Asp isomerization in CADM1 shedding products is potentially involved in neurodegeneration induced by elevated pressure
    (2023)
ｍore...
Education (4)：
  • - 1998 Kobe University School of Medicine Faculty of Medicine
  • - 1998 Kobe University Faculty of Medicine
  • - 1995 Osaka University
  • - 1995 Osaka University Graduate School, Division of Medicine
Professional career (1)：
  • (BLANK)
Awards (4)：
  • 2002 - 日本がん転移学会学術奨励賞
  • 2001 - 日本病理学会学術奨励賞
  • 日本がん転移学会研究奨励賞
  • 日本病理学会学術奨励賞
Association Membership(s) (2)：
日本病理学会 ,  日本癌学会
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