Otsubo Tadamune

オオツボタダムネ | Otsubo Tadamune

Affiliation and department：
Job title： Associate Professor

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (6)：インフルエンザ , 蛍光プローブ , シアリダーゼ・ノイラミニダーゼ , Chemical Biology , 糖鎖化学 , 不斉反応・不斉認識

Research theme for competitive and other funds (5)：

2017 - 2020 Development of companion diagnostics for detection of influenza virus resistant drugs
2018 - 2019 抗インフルエンザ薬の耐性ウイルスを簡便に判別する技術
2017 - 2018 インフルエンザウイルスの耐性薬剤を迅速簡便に識別する技術
2014 - 2017 Study on development and application of histochemically stainable probe using fluorescent pigment dye
2000 - 2002 光学活性ホモオキサカリックス[3]アレン誘導体の合成と機能

Papers (45)：

Akira Minami, Yuuki Kurebayashi, Tadanobu Takahashi, Tadamune Otsubo, Kiyoshi Ikeda, Takashi Suzuki. The Function of Sialidase Revealed by Sialidase Activity Imaging Probe. International journal of molecular sciences. 2021. 22. 6
Akira Minami, Yuka Fujita, Jun Goto, Ayano Iuchi, Kosei Fujita, Yasuyo Mikami, Mako Shiratori, Ami Ishii, Samir Mitragotri, Yasunori Iwao, et al. Enhancement of elastin expression by transdermal administration of sialidase isozyme Neu2. SCIENTIFIC REPORTS. 2021. 11. 1. 3302-3302
Tadanobu Takahashi, Yuuki Kurebayashi, Tadamune Otsubo, Kiyoshi Ikeda, Akira Minami, Takashi Suzuki. Live Imaging of Virus-Infected Cells by Using a Sialidase Fluorogenic Probe. Methods in molecular biology (Clifton, N.J.). 2021. 2274. 141-154
Yuuki Kurebayashi, Tadanobu Takahashi, Tadamune Otsubo, Akira Minami, Kiyoshi Ikeda, Takashi Suzuki. Detection and Isolation of a Drug-Resistant Influenza Virus Using a Sialidase Fluorescence Imaging Technique. TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY. 2020. 32. 186. E37-E43
Akira Minami, Yuka Fujita, Sumika Shimba, Mako Shiratori, Yukiko K. Kaneko, Toshiaki Sawatani, Tadamune Otsubo, Kiyoshi Ikeda, Hiroaki Kanazawa, Yasuyo Mikami, et al. The sialidase inhibitor 2,3-dehydro-2-deoxy-N-acetylneuraminic acid is a glucose-dependent potentiator of insulin secretion. SCIENTIFIC REPORTS. 2020. 10. 1. 5198-5198

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MISC (6)：

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Patents (4)：

Education (3)：

Work history (4)：

2009/04 - 現在 Hiroshima International University Faculty of Pharmaceutical Sciences
2004/04 - 2009/03 Hiroshima International University Faculty of Pharmaceutical Sciences
2003/04 - 2004/03 Chuo University
2000/04 - 2003/03 日本学術振興会特別研究員

Association Membership(s) (7)：

日本応用糖質科学会 , 日本糖質学会 , アメリカ化学会 , 日本化学会 , 日本ケミカルバイオロジー学会 , 有機合成化学協会 , 日本薬学会

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