INOUE Ryuji

イノウエリュウジ | INOUE Ryuji

Affiliation and department：
Homepage URL (2)： http://www.med.fukuoka-u.ac.jp/physiol/ , http://www.med.fukuoka-u.ac.jp/physiol/

Research field (1)： General pharmacology

Research keywords (6)： voltage- and receptor-operated Ca mobilization , TRP channel superfamily , voltage-dependent Ca channel , molecular biology , muscle physiology , model simulation

Research theme for competitive and other funds (7)：

2015 - 2019 心房細動発生機序におけるTRPMファミリーの役割の多階層解析
2012 - 2016 腎糸球体スリット膜TRPC6複合体の機械刺激受容伝達とその破綻の分子機構の解明
2010 - 2015 適応性心リモデリングとその破綻による不整脈発生機転の統合的解明
2009 - 2011 心血管Ca2+流入チャネルTRPC6蛋白質の活性化モード制御機構の解明
2008 - 2012 破骨細胞分化を制御するCa2+オシレーション形成と転写因子NFATの調節機構

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Papers (135)：

Sakamoto, Seiji; Yamaura, Kei; Numata, Tomohiro; Harada, Fumio; Amaike, Kazuma; Inoue, Ryuji; Kiyonaka, Shigeki; Hamachi, Itaru. Construction of fluorescent screening system of allosteric modulators for GABAA receptor using turn-on probe. ACS Central Science. 2019. 5. 9. 1541-1553
51 Shinichi Uchida, Yoshiyuki Asai, Yoshiaki Kariya, Kunichika Tsumoto, Hiroshi Hibino, Masashi Honma, Takeshi Abe, Fumiaki Nin, Yasutaka Kurata, Kazuharu Furutani, Hiroshi Suzuki, Hiroaki Kitano, Ryuji Inoue, Yoshihisa Kurachi. Integrative and theoretical research on the architecture of biological system and its disorder. J Physiol Sci. 2019. 69. 433-445
Onur Kerem Polat1, Masatoshi Uno, Terukazu Maruyama, Nam Ha Tran, Kayo Imamura, Chee Fah Wong, Reiko Sakaguchi, Mariko Ariyoshi, Kyohei Itsuki, Jun Ichikawa, Takashi Morii, Masahiro Shirakawa, Ryuji Inoue, Katsuhiko Asanuma, Jochen Reiser, Hidehito Tochio, Yasuo Mori, and Masayuki X. Mori. Contribution of Coiled-coil Assembly to Ca2+/Calmodulin-dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-associated Phenotypes. Journal of the American Society of Nephrology. 2019. 30. 9. 1587-1603
井上隆司、胡耀鵬、沼田朋大. TRPM4チャネルと心血管の生理・病態生理. 医学のあゆみ. 2019. 270. 10. 954-960
井上隆司、市川純、崔媛媛. TRPCサブファミリーの分子構造と活性化・制御機序の新知見. 医学のあゆみ. 2019. 270. 10. 876-882

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Books (13)：

カルシウムイオンの動員機構.In:続・生化学実験講座-情報伝達と細胞応答(上
東京化学同人 1986
Ion channels involved in responses to muscarinic receptor activation in smooth muscle. In: Sperelakis N, Kuriyama H (eds)
Elsevier/North Holland 1991
Physiology of muscarinic receptor-operated nonselective cation channels in guinea-pig ileal smooth muscle. In : Nonselective cation channels : Pharmacology, Physiology and Biophysics.
Birkh(]E88D2[)user Verlag/Basel・Boston・Berlin- 1993
Calcium, calcium channel antagonists and the functioning of the gastrointestinal tract. In: IUPHAR 1994 Proceedings
Birkhäuser Verlag/Basel Switzerland 1995
Multiplicity of regulatory mechanisms for receptor-operated cation-permeable channels in guinea-pig ileum. - a possible role of mechanical forces. In: Tomita T, Bolton TB (eds): Smooth Muscle Excitation.
Academic Press 1996

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Lectures and oral presentations (86)：

Calcium- and lipid-mediated regulation of vascular receptor-activated Ca2+ channel TRPC6.
(Japan-Korea Joint Seminar 2005)
脳型KCNQ3変異体のチャネル機能解析
(西日本生理学会 2005)
脳神経に発現するKCNQ3チャネルにおけるポア領域の構造機能相関
(第83回日本生理学会 2006)
Regulation and function of vascular TRP cation channels
(FAOPS2006 symposium 2006)
大腸由来筋線維芽細胞CCD-18CoにおけるTRP蛋白質発現パターンと機能解析。
(第57回西日本生理学会 2006)

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Education (2)：

1977 - 1981 Osaka University Faculty of Medicine 医学科
1983 - 1987 Kyushu University Graduate School, Division of Medicine

Professional career (1)：

D.Med.Sci.(PhD.) (Kyushu University)

Work history (4)：

1987/06 - 1989/02 Institute for Physiology, University of Cologne, West Germany Fellow, Humboldt Foundation (West Germany)
1989/03 - 1991/02 University of Oxford postdoctoral fellow
1995 - 2005 九州大学大学院医学研究院生体情報薬理学・助教授
2005 - 現在福岡大学医学部生理学・教授

Committee career (1)：

2010/10 - 2013/07 Commission II chair

Awards (2)：

2001 - 日本心脈管作動物質学会奨励賞
1994 - Young Investigator's award (Japanese Pharmacological Society)

Association Membership(s) (4)：

日本生理学会 , Japanese Pharmacological Society , Japanese Smooth Muscle Research Society , 日本循環薬理学会

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