Rchr

J-GLOBAL ID：200901029855898620 Update date: Apr. 12, 2023

Kitajima Kenji

キタジマケンジ | Kitajima Kenji

Affiliation and department：
Job title： Researcher

Research field (3)： Cell biology , Developmental biology , Medical biochemistry

Research keywords (5)： Gata2 , Lhx2 , Transcription factor , iPSCs , Hematopoietic stem cells

Research theme for competitive and other funds (11)：

2017 - 2019 炎症性サイトカインによるマウスES細胞から造血幹細胞の誘導
2016 - 2018 ヒト造血幹細胞の発生スイッチとロードブロッカーの同定
2012 - 2014 転写因子によるヒトiPS細胞から造血幹細胞への新規分化誘導システムの開発
2011 - 2013 造血幹細胞の骨髄ニッチ脱着を制御する新規分子群の役割
2009 - 2011 細胞分化におけるエピジェネティックパターン成立機構の解明

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Papers (31)：

Kenji Kitajima, Minako Shingai, Hikaru Ando, Mako Hamasaki, Takahiko Hara. An Interferon-γ/FLT3 Axis Positively Regulates Hematopoietic Progenitor Cell Expansion from Human Pluripotent Stem Cells. Stem Cells. 2022
Kae Sato, Momoko Maeda, Eriko Kamata, Sayaka Ishii, Kanako Yanagisawa, Kenji Kitajima, Takahiko Hara. Nitric Oxide and a Conditioned Medium Affect the Hematopoietic Development in a Microfluidic Mouse Embryonic Stem Cell/OP9 Co-Cultivation System. Micromachines. 2020. 11. 3. 305-305
Nakajima M, Suzuki T, Hara T, Kitajima K. In vitro differentiation of mouse T cell-derived hybrid cells obtained through cell fusion with embryonic stem cells. Biochemical and biophysical research communications. 2019. 513. 3. 701-707
Tabata H, Hara T, Kitajima K. Inhibitory action of an ERK1/2 inhibitor on primitive endoderm cell differentiation from mouse embryonic stem cells. Biochemical and biophysical research communications. 2019. 512. 2. 399-404
Kitajima K, Kanokoda M, Nakajima M, Hara T. Domain-specific biological functions of the transcription factor Gata2 on hematopoietic differentiation of mouse embryonic stem cells. Genes to cells : devoted to molecular & cellular mechanisms. 2018. 23. 9. 753-766

ｍore...

MISC (4)：

Kenji Kitajima, Marino Nakajima, Mai Kanokoda, Michael Kyba, Abhijit Dandapat, Jakub Tolar, Megumu K. Saito, Masashi Toyoda, Akihiro Umezawa, Takahiko Hara. GSK3 beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells. EXPERIMENTAL HEMATOLOGY. 2016. 44. 1. 68-74
Kenji Kitajima, Ken-ichi Minehata, Kenji Sakimura, Toru Nakano, Takahiko Hara. In vitro generation of HSC-like cells from murine ESCs/iPSCs by enforced expression of LIM-homeobox transcription factor Lhx2. BLOOD. 2011. 117. 14. 3748-3758
K Kitajima, J Zheng, HL Yen, D Sugiyama, T Nakano. Multipotential differentiation ability of GATA-1-null erythroid-committed cells. GENES & DEVELOPMENT. 2006. 20. 6. 654-659
K Kitajima, M Kojima, K Nakajima, S Kondo, T Hara, A Miyajima, T Takeuchi. Definitive but not primitive hematopoiesis is impaired in jumonji mutant mice. BLOOD. 1999. 93. 1. 87-95

Professional career (2)：

Dr of philosophy (Hiroshima University)
- (Hiroshima University)

Work history (5)：

2009/04 - 現在東京都医学総合研究所幹細胞プロジェクト主席研究員
2005/10 - 2009/03 Osaka University Graduate School of Medicine
2002/04 - 2005/09 Osaka University Research Institute for Microbial Diseases
1999/04 - 2002/03 Osaka University Research Institute for Microbial Diseases
1996/04 - 1999/03 三菱化学生命科学研究所発生制御研究室特別研究員

Awards (5)：

2006 - 財団法人病態代謝研究会研究助成金
2005 - 財団法人大阪対がん協会がん研究助成奨励賞
2004 - 財団法人大阪対がん協会ガン研究助成奨励賞
2004 - 千里ライフサイエンス財団奨励賞
2003 - 財団法人大阪対がん協会がん研究助成奨励賞

Association Membership(s) (2)：

日本分子生物学会 , THE JAPANESE SOCIETY OF HEMATOLOGY

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