J-GLOBAL ID:200901029855898620   Update date: Oct. 21, 2019


キタジマ ケンジ | KITAJIMA Kenji
Affiliation and department:
Job title: Others
Research field  (3): Cell biology ,  Developmental biology ,  General medical chemistry
Research keywords  (5): Gata2 ,  Lhx2 ,  Transcription factor ,  iPSCs ,  Hematopoietic stem cells
Research theme for competitive and other funds  (1):
  • Differentiation of hematopoietic cells.
Papers (25):
  • Nakajima M, Suzuki T, Hara T, Kitajima K. In vitro differentiation of mouse T cell-derived hybrid cells obtained through cell fusion with embryonic stem cells. Biochemical and biophysical research communications. 2019. 513. 3. 701-707
  • Tabata H, Hara T, Kitajima K. Inhibitory action of an ERK1/2 inhibitor on primitive endoderm cell differentiation from mouse embryonic stem cells. Biochemical and biophysical research communications. 2019. 512. 2. 399-404
  • Kitajima K, Kanokoda M, Nakajima M, Hara T. Domain-specific biological functions of the transcription factor Gata2 on hematopoietic differentiation of mouse embryonic stem cells. Genes to cells : devoted to molecular & cellular mechanisms. 2018. 23. 9. 753-766
  • Miyashita K, Kitajima K, Goyama S, Kitamura T, Hara T. Overexpression of Lhx2 suppresses proliferation of human T cell acute lymphoblastic leukemia-derived cells, partly by reducing LMO2 protein levels. Biochemical and biophysical research communications. 2018. 495. 3. 2310-2316
  • Kawaguchi M, Kitajima K, Kanokoda M, Suzuki H, Miyashita K, Nakajima M, Nuriya H, Kasahara K, Hara T. Efficient production of platelets from mouse embryonic stem cells by enforced expression of Gata2 in late hemogenic endothelial cells. Biochemical and biophysical research communications. 2016. 474. 3. 462-468
MISC (3):
  • Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito MK, Toyoda M, Umezawa A, Hara T. GSK3β inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells. Experimental hematology. 2016. 44. 1. 68-74.e1
  • Kitajima K, Minehata K, Sakimura K, Nakano T, Hara T. In vitro generation of HSC-like cells from murine ESCs/iPSCs by enforced expression of LIM-homeobox transcription factor Lhx2. Blood. 2011. 117. 14. 3748-3758
  • Kitajima K, Zheng J, Yen H, Sugiyama D, Nakano T. Multipotential differentiation ability of GATA-1-null erythroid-committed cells. Genes & development. 2006. 20. 6. 654-659
Professional career (2):
  • Dr of philosophy (Hiroshima University)
  • - (Hiroshima University)
Association Membership(s) (1):
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