MIYOSHI HIDEAKI

ミヨシヒデアキ | MIYOSHI HIDEAKI

Affiliation and department：
Job title： Assistant Professor

Research field (5)： Metabolism and endocrinology , Metabolism and endocrinology , Internal medicine - General , Cell biology , Molecular biology

Research keywords (5)：動脈硬化 , 糖尿病 , 肥満 , 代謝 , perilipin

Research theme for competitive and other funds (9)：

2010 - 2013 基盤研究C
2011 - 研究助成金
2008 - 研究助成金
2007 - 研究助成金
2007 - 研究助成金

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MISC (8)：

Katherine J. Strissel, Zlatina Stancheva, Hideaki Miyoshi, James W. Perfield, Jason DeFuria, Zoe Jick, Andrew S. Greenberg, Martin S. Obin. Adipocyte death, adipose tissue remodeling, and obesity complications. DIABETES. 2007. 56. 12. 2910-2918
Sandra C. Souza, Marcelo A. Christoffolete, Miriam O. Ribeiro, Hideaki Miyoshi, Katherine J. Strissel, Zlatina S. Stancheva, Nicole H. Rogers, Tara M. D'Eon, James W. Perfield, Hitomi Imachi, et al. Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue. JOURNAL OF LIPID RESEARCH. 2007. 48. 6. 1273-1279
Hideaki Miyoshi, James W. Perfield, Sandra C. Souza, Wen-Jun Shen, Hui-Hong Zhang, Zlatina S. Stancheva, Fredric B. Kraemer, Martin S. Obin, Andrew S. Greenberg. Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes. JOURNAL OF BIOLOGICAL CHEMISTRY. 2007. 282. 2. 996-1002
H Miyoshi, SC Souza, HH Zhang, KJ Strissel, MA Christoffolete, J Kovsan, A Rudich, FB Kraemer, AC Bianco, MS Obin, et al. Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms. JOURNAL OF BIOLOGICAL CHEMISTRY. 2006. 281. 23. 15837-15844
DN Gross, H Miyoshi, T Hosaka, HH Zhang, EC Pino, S Souza, M Obin, AS Greenberg, PF Pilch. Dynamics of lipid droplet-associated proteins during hormonally stimulated lipolysis in engineered adipocytes: Stabilization and lipid droplet binding of adipocyte differentiation-related protein/adipophilin. MOLECULAR ENDOCRINOLOGY. 2006. 20. 2. 459-466

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Lectures and oral presentations (5)：

Mechanistic role of perilipin phosphorylation in regulating protein kinase A stimulated lipolysis by hormone-sensitive lipase (HSL).
(American Diabetes Association 65th Annual Scientific Sessions, Washington DC, USA 2006)
serine 517 of perilipin A is ‘master regulator’of PKA-stimulated lipolysis in adipocytes.
(American Diabetes Association 65th Annual Scientific Sessions, Washington DC, USA 2006)
Studies in Perilipin Null Adipocytes Reveal the Role of the C-terminus in Stimulated Lipolysis.
(American Diabetes Association 65th Annual Scientific Sessions, San Diego, USA 2005)
aminoguanidine pyridoxal adduct is superior to aminoguanidine for the inhibition of both oxidation and glycation.
(American Diabetes Association 62th Annual Scientific Sessions, San Francisco, USA 2002)
aminoguanidine-pyridoxal adduct is superior to aminoguanidine in preventing experimental diabetes nephropathy.
(American Diabetes Association 60th Annual Scientific Sessions, San Antonio, USA 2000)

Education (2)：

1996 - 2000 北海道大学大学院内科学専攻
1987 - 1993 Hokkaido University

Professional career (1)：

博士(医学) (Hokkaido University)

Work history (3)：

2008/01 - 北海道大学医学部第二内科助教
2005/11 - 米国タフツ大学肥満代謝科博士研究員
2003/04 - 北海道大学医学部第二内科助手

Awards (4)：

2007 - かなえ医薬振興財団研究助成金
2007 - 武田科学振興財団研究助成金
2007 - フラテ研究奨励賞
2005 - 平17年アメリカ糖尿病学会トラベルグラント

Association Membership(s) (13)：

米国糖尿病学会 , 日本病態栄養学会 , 日本動脈硬化学会 , 日本糖尿病協会(常任理事) , JAPAN SOCIETY FOR THE STUDY OF OBESITY , THE JAPAN ENDOCRINE SOCIETY , JAPAN DIABETES SOCIETY , THE JANPANESE SOCIETY OF INTERNAL MEDICINE , 米国糖尿病学会 , 日本病態栄養学会 , 日本内分泌学会 , 日本糖尿病学会 , 日本内科学会

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