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J-GLOBAL ID：200901030188161221   Update date: Aug. 11, 2024

Watanabe Nobuo

ワタナベ ノブオ | Watanabe Nobuo
Affiliation and department：
Shibaura Institute of Technology College of Systems Engineering and Science, Department of Bioscience and Engineering, College of Systems Engineering and Science Department of Bioscience & Engineering

About Shibaura Institute of Technology College of Systems Engineering and Science, Department of Bioscience and Engineering, College of Systems Engineering and Science Department of Bioscience & Engineering


Job title： Professor
Homepage URL  (1)： http://www.shibaura-it.ac.jp/faculty/systems_engineering_and_science/bioscience_and_engineering_biomedical/index.html
Research field  (7)： Hematology and oncology ,  Fluid engineering ,  Medical equipment testing ,  Hematology and oncology ,  Biophysics ,  Physiology ,  Biomedical engineering
Research theme for competitive and other funds  (5)：
  • 2024 - 2026 Prolonged ex vivo heart perfusion incorporating ventricular assist device to preserve the myocardial function
  • 2020 - 2023 Elucidation of blood cell's response to constant and fluctuating shear stresses
  • 2017 - 2020 Multidisciplinary basic studies on the shear stress related functional deterioration and damage phenomenon of erythrocytes and platelets
  • 2014 - 2016 Elucidation of Platelet Adhesion Behavior using Manufacturing technique, Confocal Microscopy, and Image Analysis
  • 2005 - 2006 心血管デバイスの物理的因子に起因する血球の損傷・破壊現象に関する総合的基礎研究
Papers (43)：
  • Yukako Ijima, Kriengsak Masnok, Juan J. Perez, Ana González-Suárez, Enrique Berjano, Nobuo Watanabe. Ablation catheter-induced mechanical deformation in myocardium: computer modeling and ex vivo experiments. Medical & Biological Engineering & Computing. 2024
  • Yugo Kato, Junhyoku Ben, Atsuto Noto, Shuntaro Kashiwaya, Yoshinori Aoki, Nobuo Watanabe, Hiroki Tsumoto, Yuri Miura, Koji Fukui. Tocotrienols Prevent the Decline of Learning Ability in High-Fat, High-Sucrose Diet-Fed C57BL/6 Mice. International Journal of Molecular Sciences. 2024. 25. 6. 3561-3561
  • Masataka Inoue, Yuki Udono, Yugo Kato, Koji Fukui, Nobuo Watanabe. Evaluation of erythrocyte membrane oxidation due to their exposure to shear flow generated by extracorporeal blood pump. The International Journal of Artificial Organs. 2024
  • Masataka Inoue, Masahiro Ohwada, Nobuo Watanabe. The shear rate promotes pinocytosis of extracellular dextran in platelets. Clinical Hemorheology and Microcirculation. 2024
  • Daichi Oshima, Megumi Yoshida, Kosuke Saga, Neo Ito, Miyu Tsuji, Atsuko Isu, Nobuo Watanabe, Ken-ichi Wakabayashi, Kenjiro Yoshimura. Mechanoresponses mediated by the TRP11 channel in cilia of Chlamydomonas reinhardtii. iScience. 2023. 26. 10. 107926-107926
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MISC (11)：
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Books (1)：
  • Blood-device interaction
    Elsevier 2017
Lectures and oral presentations  (165)：
  • ECMO中の非侵襲リアルタイム高酸素分圧推定AIの開発
    (第47回日本バイオレオロジー学会年会(東京都早稲田大学) 2024)
  • せん断応力およびADP刺激による血小板の活性化が血液凝固能に与える影響
    (第47回日本バイオレオロジー学会年会(東京都早稲田大学) 2024)
  • 組織修復研究への応用を目指した局所溶存酸素量調整装置の構築
    (第63回日本生体医工学会大会、2024年5月24日(鹿児島県カクイックス交流センター) 2024)
  • ラット僧帽筋細動脈のIn vivo観察
    (第33回ライフサポート学会フロンティア講演会(芝浦工業大学大宮キャンパス) 2024)
  • 高周波カテーテルアブレーション術におけるカテーテル先端に占める心筋接触面の重要性
    (第33回ライフサポート学会フロンティア講演会(芝浦工業大学大宮キャンパス) 2024)
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Works (6)：
  • Development of a device which allows the Generation of controllable shear stress and simultaneous microscopic observation of platelets in whole blood
    2010 -
  • Development of a device which allows the Generation of controllable shear stress and simultaneous microscopic observation of platelets in whole blood
    2010 -
  • Dynamic Deformation Behavior of Normal Human Red Blood Cells Freely Suspended in a Sinusoidally Oscillating Quasi-Couette Shear Flow: Elastic Stretching and Visco-elastic Recovering Model
    2006 -
  • Deformability of Red Blood Cells and its Relation to Blood Trauma in Rotary Blood Pumps
    2006 -
  • Dynamic Deformation Behavior of Normal Human Red Blood Cells Freely Suspended in a Sinusoidally Oscillating Quasi-Couette Shear Flow: Elastic Stretching and Visco-elastic Recovering Model
    2006 -
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Education (1)：
  • 2002 - 2006 Tokyo Medical and Dental University
Professional career (2)：
  • Ph.D. (Tokyo Medical and Dental University)
  • 修士(工学) (芝浦工業大学)
Work history (9)：
  • 2022/04 - 現在 Shibaura Institute of Technology College of Systems Engineering and Science Department of Bioscience and Engineering Professor
  • 2013/04 - 2022/03 Shibaura Institute of Technology Dept. of Bio-Science and Engineering, College of Systems Engineering and Science Associate Professor
  • 2010/04 - 2013/03 Shibaura Institute of Technology Dept. of Bio-Science and Engineering, College of Systems Engineering and Science Assistant Professor
  • 2009/10 - 2010/03 Shibaura Institute of Technology Postdoctoral research fellow
  • 2007/07 - 2009/09 Labor fuer Biofluidmechanik, Charite University Hospital, Berlin, Germany. (Head of the host Institute: Prof. Dr.-Eng Klaus Affeld)
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Awards (14)：
  • 2024/06 - 第47回日本バイオレオロジー学会年会(東京都早稲田大学) ポスター賞
  • 2021/05 - 3rd IEEE ECBIOS, Tainan, Taiwan, 28th May 2021 Best Conference Paper Award Effects of increased catheter contact force on the ablation impedance in the radiofrequency catheter ablation of cardiac arrhythmias
  • 2019/11 - 第57回日本人工臓器学会大会(JSAO 2019)、2019年11月14日, 大阪国際会議場 優秀賞(ポスター発表) 画像解析による高せん断応力下の損傷赤血球検知法の提案
  • 2007/07 - the Alexander von Humboldt Foundation, Humboldt Research Fellowships
  • 2007 - 平成19年度日本バイオレオロジー学会学術奨励賞
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Association Membership(s) (11)：
日本微小循環学会 ,  日本人工臓器学会 ,  International Society for Mechanical Circulatory Support ,  European Society for Artificial Organs ,  THE SOCIETY OF LIFE SUPPORT ENGINEERING ,  JAPANESE SOCIETY OF BIORHEOLOGY ,  日本生体医工学会 ,  IEEE Engineering in Medicine and Biology Society ,  The International Society for Rotary Blood Pumps ,  Biophysical Society ,  日本フンボルト協会
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