Otani Hiroki

オオタニヒロキ | Otani Hiroki

Affiliation and department：

Research field (2)： Anatomy , Developmental biology

Research keywords (6)：環境因子 , 遺伝因子 , 発生 , Environmental Factor , Genetic Factor , Development

Research theme for competitive and other funds (30)：

2017 - 2020 Exploration of molecules regulated by microRNAs involved in cerebral tissue formation
2015 - 2018 Exercise design based on the morphological evidence which is performed by mothers with a baby aiming at prevention of chronic post-delivery urinary incontinence
2015 - 2018 The effect of granulocyte macrophage-colony stimulating factor on histogenesis of the brain of mouse embryos
2014 - 2017 Morphological and experimental analyses of organogenesis and histogenesis of the urinary organs
2013 - 2016 Study of microRNA in histogenesis of the cerebrum in mouse embryos

2011 - 2016 Organ malformations as results of accumulated polarity disruptions in epithelial tubular structures during organogenesis and histogenesis

2011 - 2016 Regulation of polarity signaling during morphogenesis, remodeling, and breakdown of epithelial tubular structure

2011 - 2013 Evidence-based pelvic floor care for preventing postpartum urinary incontinence from becoming chronic

2010 - 2012 Mechanisms of abnormal organogenesis and histogenesis of the kidney and ureter and development of the embryonic treatment

2010 - 2012 Physiological role of maternal-fetal LIF signal relay in the development of cerebral cortex

2010 - 2012 Property of articular cartilage during maturation for a basic study of rehabilitation

2009 - 2011 Analysis of organ morphogenesis in human and mouse embryos and fetuses by the cross-ratio.

2008 - 2010 A Study on the evidence of pelvic floor muscle training to prevent chronic postpartum urinary incontinence

2007 - 2009 腎・尿管の器官・組織形成異常の形成機構に基づく治療・予防法の開発

2007 - 2009 Maternal leukemia inhibitory factor regulates fetal brain development via a maternal-fetal signaling pathway

2005 - 2006 再生医療応用を視野に入れた、消化管組織発生過程におけるREGの機能解析

2003 - 2006 Developmental analysis of neuro-immuno-endocirne network and harmonized histogenesis of organs

2002 - 2004 Development of gene transfer technique for induction of ectopic eyeballs

2002 - 2003 ES細胞の組織分化誘導による胎生期再生医学

2001 - 2003 Establishment of "In situ Knock-out" method

1998 - 2000 The Function of Leptin in Prenatal Development

1998 - 1999 Cloning and Characterization of the Hemifacial Microsomia Related Gene.

1998 - 1999 Functional analyses of roles of tyrosine kinases/phosphatases in lymhpcyte signaling

1996 - 1997 Analysis of expression and function of regulatory molecules in the whole embryos by new developmetnal engineering system

1995 - 1997 Exo utero gene introduction to specific organs and tissues during fetal and neonatal period

1994 - 1995 Systemic pattern of apoptosis in human embryos and establishment of mouse culture system to analyze its control mechanisms

1992 - 1994 Development of serial culture system for mouse whole embryos and its application for developmental engineering.

1987 - 1989 ヒト胎児期における“量的および質的"な形態指標による発生段階の設定

ヒトと実験動物における正常および異常発生に関する研究

Study on normal and abnormal development of human and experimental animal embryos.

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Papers (107)：

Shohei Fukunaga, Noriko Ogawa, Akihiro Matsumoto, Takafumi Ito, Kazuaki Tanabe, Hiroki Otani. Administration of retinoic acid to pregnant mice increases the number of fetal mouse glomeruli. Biochemistry and Biophysics Reports. 2022. 30. 101245-101245
Takuya Akai, Toshihisa Hatta, Hiromi Sakata-Haga, Seiji Yamamoto, Hiroki Otani, Shusuke Yamamoto, Satoshi Kuroda. Cerebrospinal fluid may flow out from the brain through the frontal skull base and choroid plexus: a gold colloid and cadaverine injection study in mouse fetus. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2021. 37. 10. 3013-3020
Nusrat Jahan, Esrat Jahan, Ashiq Mahmood Rafiq, Akihiro Matsumoto, Hiroki Otani. Histomorphometric analysis of the epithelial lumen, mesenchyme, smooth muscle cell layers, and mesentery of the mouse developing duodenum in relation with the macroscopic morphogenesis. Anatomical science international. 2021. 96. 3. 450-460
Akari Shintani, Hiromi Sakata-Haga, Keiichi Moriguchi, Mitsuhiro Tomosugi, Daisuke Sakai, Tsuyoshi Tsukada, Makoto Taniguchi, Masahide Asano, Hiroki Shimada, Hiroki Otani, et al. Melanocortin 5 receptor contributes to sensitivity to UV-B waves and barrier function in mouse epidermis. JID Innovations. 2021. 1. 3. 100024-100024
Dereje Getachew, Akihiro Matsumoto, Yasuhiro Uchimura, Jun Udagawa, Nanako Mita, Noriko Ogawa, Shigeru Moriyama, Akiyasu Takami, Hiroki Otani. Global pattern of interkinetic nuclear migration in tracheoesophageal epithelia of the mouse embryo: Interorgan and intraorgan regional differences. Congenital Anomalies. 2021. 61. 3. 82-96

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MISC (220)：

大谷浩, 宇田川潤, 八田稔久. 第128回生涯教育講座胎児科学をめざして(その2)出雲から展開した研究. 島根医学 : the journal of the Shimane Medical Association. 2020. 40. 2. 59-68
松尾拓哉, 籠崎有紀子, 千賀靖子, 福田博美, 篠崎圭子, 竹森久美子, 大谷浩, 近藤厚生. 女子学生のBody Mass Indexと葉酸摂取量の関係. 日本栄養・食糧学会大会講演要旨集. 2016. 70回. 283-283
松尾拓哉, 籠崎有紀子, 千賀靖子, 福田博美, 篠崎圭子, 竹森久美子, 大谷浩, 近藤厚生. 女子学生のBody Mass Indexと葉酸摂取量の関係. 日本栄養・食糧学会大会講演要旨集. 2016. 70回. 283-283
Yukiko KAGOHASHI, Hiroki OTANI. The effect of dietary fatty acid control on the improvement of glucose tolerance and diabetic nephropathy(Part2). 2016. 55. 51-59
Yukiko KAGOHASHI, Hiroki OTANI. The effect of dietary fatty acid control for the improvement of glucose tolerance and prevention of diabetic nephropathy(Part 1). 2016. 54. 149-155

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Books (6)：

人体発生学(共著)
南山堂 2003
人体解剖学(共訳)
西村書店 2003
Sobotta図説人体解剖学、第2巻体幹・内臓・下肢、第5版(共訳)
医学書院、東京 2002
解剖生理学 2002年版管理栄養士国家試験全科の要点(共著)
医歯薬出版株式会社、東京 2001
ラーセン最新人体発生学第2版(監訳)
西村書店 1999

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Works (6)：

In situ ノックアウトの確立
2001 -
Establishment of 'in situ knock-out' method
2001 -
発生に関わる調節分子の全胚における発現・機能の発生工学的解析
1996 - 1997
Systemic expression and function of developmental regulatory molecules analyzed developmental engineering
1996 - 1997
胎生期および新生児期における器官選択的遺伝子導入法の確立
1995 - 1997

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Education (2)：

- 1981 Kyoto University Faculty of Medicine Department of Medical Science
- 1981 Kyoto University Faculty of Medicine

Professional career (1)：

Dr. Medical Science (Kyoto University)

Work history (6)：

2003/10 - 現在 Shimane University Faculty of Medicine
1995/10 - 2003 Shimane Medical University
1991/09 - 1995 Shimane Medical University
1991 - 1995 Shimane Medical University, Associate Professor
1983/04 - 1991 Shimane Medical University

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Committee career (3)：

1999 - 現在日本先天異常学会評議員、理事、会長、理事長(2010,7-2019,7)
1996 - 日本重水素科学研究会会長・編集主幹
1995 - 日本解剖学会評議員

Association Membership(s) (9)：

日本重水素科学研究会 , 日本分子生物学会 , 米国解剖学会 , 国際先天異常学会 , 日本内科学会 , 日本細胞生物学会 , 日本発生生物学会 , 日本先天異常学会 , 日本解剖学会

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