Ohta Kunimasa

オオタクニマサ | Ohta Kunimasa

Affiliation and department：
Job title： Professor

Research field (2)： Neuroscience - general , Developmental biology

Research keywords (5)： Ribosome , Akhirin , Tsukushi , Neural stem cell , Developmental biologists

Research theme for competitive and other funds (38)：

2021 - 2023 一次生産者が細胞を細胞農業業界へ販売する社会を実現するための基礎技術の開発
2021 - 2022 Akhirinによるマウス脳神経幹細胞の制御
2021 - 2022 リボソームによる単細胞生物から多細胞生物への形質転換
2020 - 2021 大規模培養装置CulNet systemに用いる人工臓器部位作出
2019 - 2021 リボソームによる細胞のリプログラミング機構の解明

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Papers (84)：

Orasa Panawan, Atit Silsirivanit, Chih-Hsiang Chang, Siyaporn Putthisen, Piyanard Boonnate, Taro Yokota, Yuki Nishisyama-Ikeda, Marutpong Detarya, Kanlayanee Sawanyawisuth, Worasak Kaewkong, et al. Establishment and characterization of a novel cancer stem-like cell of cholangiocarcinoma. Cancer science. 2023
Arif Istiaq, Kunimasa Ohta. A review on Tsukushi: mammalian development, disorders, and therapy. Journal of cell communication and signaling. 2022. 16. 4. 505-513
Arif Istiaq, Terumasa Umemoto, Naofumi Ito, Toshio Suda, Kenji Shimamura, Kunimasa Ohta. Tsukushi proteoglycan maintains RNA splicing and developmental signaling network in GFAP-expressing subventricular zone neural stem/progenitor cells. Frontiers in Cell and Developmental Biology. 2022. 10. 994588-994588
Sabrina Quaresima, Arif Istiaq, Hirofumi Jono, Emanuele Cacci, Kunimasa Ohta, Giuseppe Lupo. Assessing the Role of Ependymal and Vascular Cells as Sources of Extracellular Cues Regulating the Mouse Ventricular-Subventricular Zone Neurogenic Niche. Frontiers in cell and developmental biology. 2022. 10. 845567-845567
Siyaporn Putthisen, Atit Silsirivanit, Orasa Panawan, Akiko Niibori-Nambu, Yuki Nishiyama-Ikeda, Prasertsri Ma-In, Sukanya Luang, Kunimasa Ohta, Kanha Muisuk, Sopit Wongkham, et al. Targeting alpha 2,3-sialylated glycan in glioma stem-like cells by Maackia amurensis lectin-II: A promising strategy for glioma treatment. Experimental Cell Research. 2022. 410. 1. 112949-112949

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MISC (35)：

Kunimasa Ohta. regulation of brain neural stem cell niche by proteoglycan Tsukushi. 2022. 280. 3. 234-235
Arif Istiaq and Kunimasa Ohta. Ribosome-Induced Cellular Multipotency, an Emerging Avenue in Cell Fate Reversal. Cells. 2021. 10. 9
Mikiko Kudo and Kunimasa Ohta. Regulation of the Brain Neural Niche by Soluble Molecule Akhirin. 2021
Istiaq, A., Ahmad, S.A.I., Anam, M.B., Kudo, M., Nakayama, S., et al. Bacteria to form induced pluripotent stem cells. 2021
工藤三希子, 伊藤尚文, 河野利恵, 太田訓正. 毛周期調節におけるTsukushiとTGFβシグナル. 2019

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Patents (2)：

METHOD FOR INDUCING CELL REPROGRAMMING, AND METHOD FOR PRODUCING PLURIPOTENT CELLS
発酵能を有する細菌を用いた多能性細胞の製造方法

Books (11)：

毛周期におけるTsukushiとTGF - βシグナル
シーエムシー出版 2019 ISBN:9784781314341
Reprogramming of cells by lactic acid bacteria
Springer Singapore 2018
乳酸菌による細胞リプログラミング
シーエムシー出版 2018 ISBN:9784781313177
Cell reprogramming by Lactic Acid Bacteria
Applied RNA Biosciences. (Eds. Matsuda S. and Izawa S.) 2018
The Role of Tsukushi as an Extracellular Signaling Coordinator
2014

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Lectures and oral presentations (229)：

分泌型タンパク質Akhirinによる脳神経幹細胞ニッチの制御
(日本CCNファミリー研究会 2022)
Cellar dynamics in Exo-ribosome mediated multipotency induction in somatic cells
(第3回日独合同若手ミーティング 2021)
Akhirin regulates neural stem cell proliferation through microglial activation
(第3回日独合同若手ミーティング 2021)
DYSFUNCTION OF THE PROTEOGLYCAN TSUKUSHI CAUSES HYDROCEPHALUS THROUGH ALTERED NEUROGENESIS IN THE SUBVENTRICULAR ZONE IN MICE
(ISSCR/JSRM 2021 virtual Tokyo International Symposium 2021)
Akhirin regulates neural stem cell proliferation through microglial activation
(第64回日本神経化学会大会 2021)

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Works (8)：

リボソームによる細胞リプログラミング機構の解析
2013 - 現在
Tsukushiと水頭症発症の連関
太田訓正 2012 - 現在
Akhirinによる神経幹細胞ニッチの制御
2005 - 現在
乳酸菌を介した細胞リプログラム機構の解析
2010 - 2012
網膜神経幹細胞におけるBMPアンタゴニストTsukushiの機能解析
2007 - 2011

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Education (3)：

1989 - 1992 Kyushu University Graduate School, School of Medicine
1987 - 1989 Kyushu University Graduate School, Division of Sciences
1983 - 1987 Kyushu University School of Sciences Department of Biology

Professional career (1)：

Doctor of Science (Kyushu University)

Work history (8)：

2020/04 - 現在 Kyushu University Faculty od Arts and Science Professor
2011/01 - 2020/03 Kumamoto University Faculty of Life Sciences Department of Developmental Neurobiology
2007/01 - 2010/12 Kumamoto University Faculty of Life Sciences
2004 - 2007 熊本大学大学院医学薬学研究部神経分化学助教授
2001 - 2005 科学技術振興事業団さきがけ研究21 研究員(兼任)

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Committee career (13)：

2022/04 - 現在基幹教育セミナー班長
2021/04 - 現在神経発生討論会世話人
2020/08 - 現在日本CCNファミリー研究会幹事
2014 - 現在 The International CCN Society (ICCNS) adviser
2021/04 - 2023/03 九州大学全学学生支援委員会課外活動支援専門部会部会長

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Awards (2)：

2015 - 大阪府彩都賞
2005 - 熊本医学会熊本医学会奨励賞

Association Membership(s) (5)：

The Molecular Biology Society of Japan , JAPANESE SOCIETY of DEVELOPMENTAL BIOLOGISTS , The Japan Neuroscience Society , INTERNATIONAL SOCIETY FOR STEM CELL RESEARCH (ISSCR) , The International CCN Society (ICCNS)

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