Rchr
J-GLOBAL ID：200901030890690305   Update date: Apr. 03, 2024

Kamisuki Shinji

カミスキ シンジ | Kamisuki Shinji
Affiliation and department：
Azabu University School of Veterinary Medicine, Department of Veterinary Medicine

About Azabu University School of Veterinary Medicine, Department of Veterinary Medicine


Homepage URL  (1)： https://lab-navi.azabu-u.ac.jp/v-01-chemi/
Research field  (1)： Bioorganic chemistry
Research keywords  (10)： 真菌 ,  放線菌 ,  微生物二次代謝産物 ,  anticancer compounds ,  nuclear hormone receptors ,  Neuroprotective compounds ,  Antiviral agents ,  Reactive nitrogen species ,  天然物化学 ,  ケミカルバイオロジー
Research theme for competitive and other funds  (9)：
  • 2021 - 2024 Studies on the mechanism of action of pestalotioquinol A that protects cells from reactive nitrogen species
  • 2018 - 2021 Elucidation of the mechanism of reactive nitrogen species-induced neuronal cell death using small molecules
  • 2015 - 2018 Target identification and mechanism of action of neoechinulin A
  • 2015 - 2016 抗ウイルス抗体を産生する新規抗ウイルス剤EdAPの研究
  • 2015 - ネオエキヌリンA の標的分子の同定と作用機構解明
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Papers (91)：
  • Hironobu Murakami, Yuuta Fujikawa, Masaya Mori, Nozomi Mosu, Akihiro Taguchi, Yoshio Hayashi, Hideshi Inoue, Shinji Kamisuki. Development of a novel fluorogenic assay method for screening inhibitors of bovine leukemia virus (BLV) protease and identification of mitorubrinic acid as an anti-BLV compound. Bioscience, biotechnology, and biochemistry. 2023
  • Kou Nakamura, Masako Yamasaki, Hirofumi Ohashi, Shiki Saito, Koudai Ashikawa, Kanna Sato, Kazane Nishioka, Yuka Suzuki, Yukine Tsurukawa, Kazuki Kanno, et al. Identification of methylsulochrin as a partial agonist for aryl hydrocarbon receptors and its antiviral and anti-inflammatory activities. Chemical & pharmaceutical bulletin. 2023
  • Shinji Kamisuki, Hisanobu Shibasaki, Hironobu Murakami, Kan Fujino, Senko Tsukuda, Ikumi Kojima, Koudai Ashikawa, Kazuki Kanno, Tomohiro Ishikawa, Tatsuo Saito, et al. Isolation, structural determination, and antiviral activities of metabolites from vanitaracin A-producing Talaromyces sp. The Journal of antibiotics. 2023. 76. 2. 75-82
  • Hirofumi Ohashi, Kazane Nishioka, Tomoki Kurihara, Kou Nakamura, Masako Yamasaki, Yuuka Ibayashi, Kanta Fuchiyama, Shogo Kamo, Yuuki Furuyama, Kenji Ohgane, et al. Anti-hepatitis C Virus Activity of Juglorubin Derivatives. Chemical & pharmaceutical bulletin. 2023. 71. 11. 843-845
  • Rimina Suzuki, Mayuko Mishima, Masaki Nagane, Hinano Mizugaki, Takehito Suzuki, Mariko Komuro, Takuto Shimizu, Tomoki Fukuyama, Shiro Takeda, Masaya Ogata, et al. The novel sustained 3-hydroxybutyrate donor poly-D-3-hydroxybutyric acid prevents inflammatory bowel disease through upregulation of regulatory T-cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 1. e22708
ｍore...
MISC (33)：
  • 渕山幹太, 浅川竜輝, 中村洸, 古山祐貴, 紙透伸治, 紙透伸治, 大金賢司, 倉持幸司. Synthesis and biological activities of eucalyptin and its derivatives. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
  • 模素希, 中村洸, 谷田貝紗有, 加瀬ちひろ, 加瀬ちひろ, 相原尚之, 相原尚之, 片平浩孝, 風間啓, 内山淳平, et al. Analysis of animal-derived rare actinomycetes as a new source of bioactive compounds. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
  • 齋藤史季, 太田垣潤一郎, 大橋啓史, 西岡華実, 中村洸, 鶴川幸音, 柴崎久宣, 菅野和紀, 村上裕信, 永根大幹, et al. Discovery of a Novel LXR antagonist and its anti-hepatitis C virus activity. 日本農芸化学会大会講演要旨集(Web). 2021. 2021
  • 鶴川幸音, 菅野和紀, 鈴木優華, 村上裕信, 竹田志郎, 永根大幹, 坂上元栄, 曽川一幸, 篠田陽, 紙透伸治. Investigation of the cytoprotective against RNS-induced cytotoxicity mechanism and evaluation of its anti-inflammation activity. 日本農芸化学会大会講演要旨集(Web). 2021. 2021
  • 鶴川幸音, 菅野和紀, 鈴木優華, 村上裕信, 竹田志郎, 永根大幹, 坂上元栄, 篠田陽, 紙透伸治. The mechanism of action of a novel neuroprotective compound, pestalotioquinol A. 日本農芸化学会大会講演要旨集(Web). 2020. 2020
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Patents (12)：
  • 肝臓X受容体アンタゴニスト
  • 牛白血病ウイルスに対する薬剤スクリーニング法
  • アデニン誘導体又はその薬理学的に許容しうる塩、その製造方法、及びその用途
  • 抗癌活性を有する化合物
  • DNAポリメラーゼ阻害活性を有する新規化合物
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Lectures and oral presentations  (3)：
  • 真菌由来の新規生理活性物質の探索
    (第3回天然物化学研究会 2015)
  • 細胞毒性をもつ小分子の作用機構解析
    (新学術領域研究 天然物ケミカルバイオロジー地区ミニシンポジウム 2014)
  • 脂肪合成を阻害する小分子化合物
    (日本植物学会 2010)
Education (3)：
  • 2002 - 2005 Tokyo University of Science Graduate School, Division of Science and Engineering Department of Applied Biological Science
  • 2000 - 2002 Tokyo University of Science Graduate School, Division of Science and Engineering Department of Applied Biological Science
  • 1996 - 2000 Tokyo University of Science Faculty of Science and Engineering Department of Applied Biological Science
Work history (6)：
  • 2019/04 - 現在 麻布大学大学院 獣医学研究科 准教授
  • 2015/04 - 2019/03 Azabu University School of Veterinary Medicine
  • 2011/04 - 2015/03 Tokyo University of Science Faculty of Science and Technology
  • 2009/04 - 2011/03 理化学研究所 袖岡有機合成化学研究室 ERATO袖岡生細胞分子化学プロジェクト研究員
  • 2006/04 - 2009/03 Kyoto University Institute for Chemical Research
Show all
Association Membership(s) (4)：
アメリカ化学会 ,  日本ケミカルバイオロジー学会 ,  日本農芸化学会 ,  日本薬学会
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