Rchr
J-GLOBAL ID:200901031425113233
Update date: Jun. 08, 2020
Kobayakawa Takeshi
コバヤカワ タケシ | Kobayakawa Takeshi
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Affiliation and department:
長崎大学 大学院医歯薬学総合研究科 医療科学専攻
About 長崎大学 大学院医歯薬学総合研究科 医療科学専攻
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Detailed information
Job title:
技術専門職員
Research field (1):
Oral medicine
Research theme for competitive and other funds (3):
1982 - 2004 軟骨プロテオグリカンの研究
2001 - 分子シャペロンの構造と機能
2001 - Structure and function of molecular chaperons
Papers (4):
Nemoto TK, Ono T, Kobayakawa T, Ohara-Nemoto Y. Characterization of bacterial acylpeptidyl-oligopeptidase. Biochimie. 2019. 163. 50-57
Yuko Ohara-Nemoto, Manami Nakasato, Yu Shimoyama, Tomomi T. Baba, Takeshi Kobayakawa, Toshio Ono, Takashi Yaegashi, Shigenobu Kimura, Takayuki K. Nemoto. Degradation of Incretins and Modulation of Blood Glucose Levels by Periodontopathic Bacterial Dipeptidyl Peptidase 4. INFECTION AND IMMUNITY. 2017. 85. 9
Yuko Ohara-Nemoto, Shakh M. A. Rouf, Mariko Naito, Amie Yanase, Fumi Tetsuo, Toshio Ono, Takeshi Kobayakawa, Yu Shimoyama, Shigenobu Kimura, Koji Nakayama, et al. Identification and Characterization of Prokaryotic Dipeptidyl-peptidase 5 from Porphyromonas gingivalis. JOURNAL OF BIOLOGICAL CHEMISTRY. 2014. 289. 9. 5436-5448
Toshio Ono, Yuko Ohara-Nemoto, Yu Shimoyama, Hisami Okawara, Takeshi Kobayakawa, Tomomi T. Baba, Shigenobu Kimura, Takayuki K. Nemoto. Amino acid residues modulating the activities of staphylococcal glutamyl endopeptidases. BIOLOGICAL CHEMISTRY. 2010. 391. 10. 1221-1232
MISC (13):
Takeshi Kobayakawa, Shin-ichi Yamada, Akio Mizuno, Yuko Ohara-Nemoto, Tomomi T. Baba, Takayuki K. Nemoto. Single Nucleotide Polymorphism that Accompanies a Missense Mutation (Gln488His) Impedes the Dimerization of Hsp90. PROTEIN JOURNAL. 2009. 28. 1. 24-28
Takeshi Kobayakawa, Shin-ichi Yamada, Akio Mizuno, Takayuki K. Nemoto. Substitution of only two residues of human Hsp90 alpha causes impeded dimerization of Hsp90 beta. CELL STRESS & CHAPERONES. 2008. 13. 1. 97-104
Takeshi Kobayakawa, Shin-ichi Yamada, Akio Mizuno, Takayuki K. Nemoto. Substitution of only two residues of human Hsp90 alpha causes impeded dimerization of Hsp90 beta. CELL STRESS & CHAPERONES. 2008. 13. 1. 97-104
Takayuki K. Nemoto, Yuko Ohara-Nemoto, Toshio Ono, Takeshi Kobayakawa, Yu Shimoyama, Shigenobu Kimura, Takashi Takagi. Characterization of the glutamyl endopeptidase from Staphylococcus aureus expressed in Escherichia coli. FEBS JOURNAL. 2008. 275. 3. 573-587
Takayuki K. Nemoto, Yuko Ohara-Nemoto, Toshio Ono, Takeshi Kobayakawa, Yu Shimoyama, Shigenobu Kimura, Takashi Takagi. Characterization of the glutamyl endopeptidase from Staphylococcus aureus expressed in Escherichia coli. FEBS JOURNAL. 2008. 275. 3. 573-587
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Lectures and oral presentations (20):
バイオミネラリゼーションを誘導する細胞外マトリックス成分と機構について
(三学会合同長崎例会 2008)
ニワトリ腱組織の異所性石灰化ヒドロキシアパタイト形成機構について
(第7回日本化学会西日本大会 2008)
ヒトHsp90αSNP Gln488>His変異によるHsp90ダイマー形成能の低下
(第80回日本生化学会および第30回日本分子生物学会(合同) 2007)
S. aureusグルタミン酸特異的プロテアーゼの大腸菌発現とin vitro mutagenesisによる重要アミノ酸の役割の検討
(第80回日本生化学会および第30回日本分子生物学会(合同) 2007)
Hsp90α遺伝子多型Gln488>Hisはダイマー形成能の低下をきたす
(第2回臨床ストレス応答学会 2007)
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Works (1):
癌治療ターゲット分子シャペロン機能の解明とその応用
2006 - 2008
Association Membership(s) (1):
日本生化学会
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