Ishii Toshiaki

イシイトシアキ | Ishii Toshiaki

Affiliation and department：
Homepage URL (1)： http://www.obihiro.ac.jp/~yakuri141/

Research field (1)： Veterinary medicine

Research keywords (29)：バイオマーカー , CYP , ILK , 神経変性疾患 , 細胞接着 , 神経分化 , 食情報 , 学習 , 記憶 , 認知 , 脳神経系 , 探索行動 , 自給本能 , 離乳 , Feeding , Me5 , Exploratory behavior , Feeding behavior , Seeking behavior , Weaning , Alzheimer's disease , Tau , Neurite , Neuronal differentiation , Brain , Neuronal cell , Neuron , Integrin-linked kinase , Integrin

Research theme for competitive and other funds (21)：

2023 - 2026 てんかんの発症予防に有効なプロバイオティクスの作用機構と脳腸相関
2023 - 2024 腸内細菌と神経保護作用に関する研究
2020 - 2023 難治性認知症の発症予防に有効なプロバイオティクスの作用機構と脳腸相関
2020 - 2021 パーキンソン病(PD)に併発する難治性認知障害の治療薬
2017 - 2021 腸内細菌と脳腸相関に関する研究

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Papers (96)：

Yoshikage Muroi, Toshiaki Ishii. Neuronal stress-coping mechanisms in postpartum females. Neuroscience Research. 2025
Haruka SHIMIZU, Yuri SADAKUNI, Yoshikage MUROI, Toshiaki ISHII. Dopamine D2 receptor agonists prevent impairment of maternal care in lipopolysaccharide-induced postpartum depression model mice. Journal of Veterinary Medical Science. 2025
Toshiaki Ishii, Motohiro Kaya, Yoshikage Muroi. Oral Administration of Probiotic Bifidobacterium breve Ameliorates Tonic-Clonic Seizure in a Pentylenetetrazole-Induced Kindling Mouse Model via Integrin-Linked Kinase Signaling. International journal of molecular sciences. 2024. 25. 17
Ikuko Horie, Yoshikage Muroi, Toshiaki Ishii. Noradrenergic Regulation of the Medial Prefrontal Cortex Mediates Stress Coping in Postpartum Female Mice. Molecular Neurobiology. 2024. 62. 1. 137-155
Ayane Nakamura, Yoshikage Muroi, Toshiaki Ishii. Locus Coeruleus-Noradrenergic Neurons Regulate Stress Coping During Subchronic Exposure to Social Threats: A Characteristic Feature in Postpartum Female Mice. Cellular and Molecular Neurobiology. 2023. 43. 5. 2359-2376

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MISC (63)：

Satoru Kamada, Toyomi Takahashi, Motohiro Kaya, Kazuro Miyahara, Toshiaki Ishii. Inhibition of hyaluronidase activity by Omnipark;a contrast agent;observed during the;basic study of canine chemonucleolysis therapy. Journal of Animal Clinical Medicine. 2021. 30. 2. 40-45
釜田悟, 高橋響, 宮内聡, 嘉屋元博, 宮原和郎, 石井利明. ヒアルロニダーゼ活性の高感度測定方法の検討と犬尿中ヒアルロニダーゼの特性解析. 動物臨床医学. 2020. 29. 4. 146-151
山崎栄樹, 楠本晃子, 七戸新太郎, 福本晋也, 菅沼啓輔, 横山直明, 五十嵐郁男, 玄学南, 倉園久生, 石井利明, et al. 大学におけるISO/IEC17025認定取得の取り組み. 日本食品微生物学会学術総会講演要旨集. 2017. 38th. 89
Muroi, Y., Horie, I., & Ishii, T. Lactating females increase stress resistance following chronic restraint stress in mice. J. Pharmacol. Sci. 2017. 133. suppl.1. 225
Yoshikage Muroi, Toshiaki Ishii. Neuropeptide Y in the dorsal raphe nucleus inhibits expression of maternal behavior in mice. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. suppl.1. 190P-190P

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Patents (7)：

抗てんかん用組成物
パーキンソン病に併発した認知障害の治療剤
パーキンソン病に併発した記憶消失亢進を改善するための剤及びベルセトラグ誘導体
パーキンソン病に併発した認知障害の治療剤及びそのスクリーニング方法
動物の汚染調査方法

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Books (7)：

Lactoferrin stimulates cell growth and survival in neuronal cells via activation of integrin-dependent signals.
Current Topics in Pharmacology 13:67-73.(Review)(Reserch Trends) 2009
Role of integrin-linked kinase in neuronal cells.
Current Enzyme Inhibition. (Review) 1: 3-10, 2005. 2005
Long-term effect of ouabain: Transcriptional regulation of the Na/K-ATPase α1 subunit gene under ouabain treatment.
In "Na/K-ATPase and Related ATPases", 697-700, (Ed. K. Taniguchi & S. Kaya). ELSEVIER (Excerpta Medica, ICS 1207), 2000. 2000
Effect of Oligomycin on Interaction of Na+ with Na+,K+-ATPase.
In "Na/K-ATPase and Related ATPases", 451-454, (Ed. K. Taniguchi & S. Kaya). ELSEVIER (Excerpta Medica, ICS 1207), 2000. 2000
The Na+/K+-ATPase: Molecular dissection of functional domains.
In "Membrane Proteins:Structure, function and expression control ", 281-297, (Ed. N. Hamasaki & K.Katsuyoshi). S Karger Pub, 1997. 1997

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Professional career (1)：

Committee career (2)：

1995 - 日本獣医学会学術評議員
1995 - 日本薬理学会学術評議員

Association Membership(s) (7)：

米国神経科学会 , 日本分子生物学会 , 日本獣医学会 , 日本生化学会 , 日本薬理学会 , 日本神経化学会 , 日本神経科学会

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