Rchr
J-GLOBAL ID:200901032604573626   Update date: Sep. 23, 2024

Asai Tomohiro

アサイ トモヒロ | Asai Tomohiro
Affiliation and department:
Job title: Assistant Professor
Research field  (1): Pharmaceuticals - health and biochemistry
Research keywords  (3): DDS ,  Medical molecular biology ,  Biochemistry
Research theme for competitive and other funds  (27):
  • 2022 - 2025 抗原提示細胞を標的としたmRNA/LNP製剤の開発と個別化がん免疫療法への応用
  • 2020 - 2022 Design and construction of neutrophil-mediated drug delivery system
  • 2019 - 2022 Clarification of the molecular mechanism and establishment of the basis for drug development toward epithelial cancer barrier
  • 2019 - 2022 Development of plastic antibodies that inhibit intestinal absorption of target molecules
  • 2018 - 2021 Innovative DDS medicine for the complete recovery from autoimmune diseases
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Papers (166):
  • Katsuki Matayoshi, Furan Song, Hiroyuki Koide, Sei Yonezawa, Chiori Nitta, Masako Okada, Nahoko Ozaki, Makiko Kurata, Tomohiro Asai. Delivery of small interfering ribonucleic acid using lipid nanoparticles prepared with pH-responsive dipeptide-conjugated lipids. Biochemical and Biophysical Research Communications. 2024. 150372-150372
  • Hiroyuki Koide, Chiaki Kiyokawa, Anna Okishima, Kaito Saito, Keiichi Yoshimatsu, Tatsuya Fukuta, Yu Hoshino, Tomohiro Asai, Yuri Nishimura, Yoshiko Miura, et al. Design of an Anti-HMGB1 Synthetic Antibody for In Vivo Ischemic/Reperfusion Injury Therapy. Journal of the American Chemical Society. 2023
  • Masahiro Hashimoto, Sei Yonezawa, Song Furan, Chiori Nitta, Noriyuki Maeda, Koji Tomita, Ayano Yokouchi, Hiroyuki Koide, Tomohiro Asai. Increasing the siRNA knockdown efficiency of lipid nanoparticles by morphological transformation with the use of dihydrosphingomyelin as a helper lipid. Biomaterials science. 2023. 11. 9. 3269-3277
  • Hiroyuki Koide, Kazuhiro Saito, Keiichi Yoshimatsu, Beverly Chou, Yu Hoshino, Sei Yonezawa, Naoto Oku, Tomohiro Asai, Kenneth J Shea. Cooling-induced, localized release of cytotoxic peptides from engineered polymer nanoparticles in living mice for cancer therapy. Journal of controlled release : official journal of the Controlled Release Society. 2023. 355. 745-759
  • Tomohiro Asai, Masafumi Yokota, Hideki Isomura, Hiroyuki Koide, Naoyuki Sakurai, Ayaka Okamoto, Hidenori Ando, Takehisa Dewa, Naoto Oku. Treatment of PTEN-Null Breast Cancer by a Synthetic Lethal Approach Involving PARP1 Gene Silencing. Journal of pharmaceutical sciences. 2023
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MISC (47):
  • 渡邊翠, 小出裕之, 平田真也, 米澤正, 出羽毅久, 奥直人, 奥直人, 浅井知浩. Development of protein delivery strategy using multi-functionalized liposomes. 日本薬剤学会年会講演要旨集(CD-ROM). 2023. 38th
  • 又吉克樹, 龍聡平, 高橋沙也加, 米澤正, 尾崎奈穂子, 田中陽平, 浅井知浩. 新規pH応答性ペプチド脂質を基盤とするmRNA/LNP製剤の設計. 生体膜と薬物の相互作用シンポジウム講演要旨集. 2022. 43rd
  • 安野豪, 小出裕之, 米澤正, 浅井知浩. Influence of purification method of synthetic polymer nanoparticle on the function. 日本薬学会年会要旨集(Web). 2021. 141st
  • 米澤正, 林純衣, 小出裕之, 川崎靖, 杉山晶規, 浅井知浩. Development of tubulointerstitial-targeting drug delivery system in Zucker Diabetic Fatty Rat. 日本薬学会年会要旨集(Web). 2021. 141st
  • 宋復燃, 森本誠士郎, 山本裕和, 小出裕之, 米澤正, 浅井知浩. 血栓標的化2剤内封リポソームの開発とがん治療応用. 日本DDS学会学術集会プログラム予稿集. 2021. 37th
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Books (5):
  • DDS先端技術の製剤への応用開発
    株式会社 技術情報協会 2017
  • リポソーム応用の新展開
    株式会社 エヌ・ティー・エス 2015
  • DDSキャリア作成プロトコル集
    株式会社 シーエムシー出版 2015
  • DDS技術の実用化手法
    株式会社 技術情報協会 2013
  • 非経口投与製剤の開発と応用-次世代型医薬品の新規投与形態の開拓を目指して-
    株式会社 シーエムシー出版 2013
Education (1):
  • - 1998 University of Shizuoka Graduate School, Division of Pharmaceutical Sciences
Professional career (1):
  • (BLANK)
Work history (7):
  • 2018/04 - 現在 University of Shizuoka School of Pharmaceutical Sciences
  • 2013/04 - 2018/03 University of Shizuoka School of Pharmaceutical Sciences
  • 2004/02 - 2013/03 University of Shizuoka School of Pharmaceutical Sciences
  • 2011/07 - 2012/06 University of North Carolina・Visiting Scholar
  • 2005/10 - 2005/12 University of North Carolina・Visiting Scholar
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Awards (9):
  • 2016/03 - 静岡県立大学教員活動評価学長表彰
  • 2014/05 - 日本薬剤学会奨励賞
  • 2011/07 - 日本薬学会東海支部奨励賞
  • 2011/03 - 日本薬学会奨励賞
  • 2009/10 - The APSTJ Global Education Seminar Presentation Award 2009
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Association Membership(s) (5):
THE JAPANESE BIOCHEMICAL SOCIETY ,  日本薬剤学会 ,  日本DDS学会 ,  日本薬学会 ,  日本核酸医薬学会
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