2007 - 2008 Mechanosensing mechanism organized by periostin in periodontal ligament and periosteum
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Papers (63)：
Mizuki Aoyama, Ninako Kimura, Masato Yamakawa, Sora Suzuki, Koji Umezawa, Isao Kii. DnaK promotes autophosphorylation of DYRK1A and its family kinases in Escherichia coli-based cell-free protein expression. Biochemical and biophysical research communications. 2023. 688. 149220-149220
Ninako Kimura, Kanako Saito, Takashi Niwa, Masato Yamakawa, Shota Igaue, Junko Ohkanda, Takamitsu Hosoya, Isao Kii. Expression and purification of DYRK1A kinase domain in complex with its folding intermediate-selective inhibitor FINDY. Protein expression and purification. 2022. 195-196. 106089-106089
Yuka Miyazaki, Masaki Kikuchi, Koji Umezawa, Aurelie Descamps, Daichi Nakamura, Gaku Furuie, Tomoe Sumida, Kanako Saito, Ninako Kimura, Takashi Niwa, et al. Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. European journal of medicinal chemistry. 2022. 227. 113948-113948
Takashi Nishiyama, Koji Umezawa, Kentaro Yamada, Masaharu Takahashi, Satoshi Kunita, Mulyanto, Isao Kii, Hiroaki Okamoto. The Capsid (ORF2) Protein of Hepatitis E Virus in Feces Is C-Terminally Truncated. Pathogens (Basel, Switzerland). 2021. 11. 1
Masayasu Toyomoto, Asuka Inoue, Kei Iida, Masatsugu Denawa, Isao Kii, Francois Marie Ngako Kadji, Takayuki Kishi, Dohyun Im, Tatsuro Shimamura, Hiroshi Onogi, et al. S1PR3-G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation. Cell chemical biology. 2021. 28. 8. 1132-1144
Kosuke Kawaguchi, Eiji SUzuki, Masashi Inoue, Isao Kii, Tatsuki R. Karaoke, Masahiro Hiram, Keiko Iwaisako, Pu Fengling, Mariko Niche, Ayane Yamaguchi, et al. Neuropilin-1 expressing macrophages promote neuropilin-1 expression on lymphocytes by direct interaction and exert antitumor activity in HER2 positive breast cancer. CANCER RESEARCH. 2016. 76
Kosuke Kawaguchi, Eiji Suzuki, Isao Kii, Tatsuki R. Kataoka, Masahiro Hirata, Hironori Haga, Masatoshi Hagiwara, Masakazu Toi. Knockdown of neuropilin-1 in monocytes impaired lymphocyte migration and anti-tumor activity in a humanized mouse model. CANCER RESEARCH. 2015. 75
Satoshi Morooka, Isao Kii, Yukiko Okuno, Nobutoshi Ito, Masatoshi Hagiwara, Nagahisa Yoshimura. Identification of a dual inhibitor of SRPK1 and CK2 that attenuates pathological angiogenesis of macular degeneration in mice. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2015. 56. 7
2002 - 2005 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
2000 - 2002 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
1996 - 2000 Tokyo Institute of Technology School of Bioscience and Biotechnology
1993 - 1996 愛媛県立今治西高等学校
Professional career (1)：
博士(理学) (東京工業大学)
Work history (10)：
2020/04 - 現在 Shinshu University
2019/04 - 2020/03 Shinshu University Faculty of Agriculture
2018/04 - 2019/03 RIKEN Unit Leader
2017/01 - 2018/03 RIKEN Unit Leader
2016/04 - 2016/12 RIKEN CLST Senior Scientist
2015/04 - 2016/03 RIKEN CLST Research Scientist
2010/08 - 2015/03 Kyoto University Research Assistant Professor
2010/07 - 2010/08 所属研究室の京都大学への移動
2010/04 - 2010/07 Tokyo medical and dental university Research Assistant Professor
2005/04 - 2010/03 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology, Department of Biological Information, Graduate School of Bioscience and Biotechnology Biological Information Assistant Professor
