Rchr
J-GLOBAL ID:200901032858213590   Update date: May. 22, 2020

Kii Isao

キイ イサオ | Kii Isao
Affiliation and department:
Homepage URL  (1): https://ikii80.wixsite.com/drugtarget
Research field  (9): Oral medicine ,  Pharmacology ,  Tumor diagnostics and therapeutics ,  Neuroscience - general ,  Biomaterials ,  Biomedical engineering ,  Molecular biology ,  Pharmaceuticals - health and biochemistry ,  Chemical biology
Research keywords  (19): tenascin ,  fibronectin ,  collagen ,  periosteum ,  periodontal ligament ,  periostin ,  high throughput assay ,  chemical library ,  chemical screening ,  selective inhibitor ,  molecular imaging ,  quality control ,  chaperone ,  DYRK1A ,  neurogenesis ,  extracellular matrix ,  chemical biology ,  folding ,  kinase
Papers (51):
  • Junshi Yazaki, Yusuke Kawashima, Taisaku Ogawa, Atsuo Kobayashi, Mayu Okoshi, Takashi Watanabe, Suguru Yoshida, Isao Kii, Shohei Egami, Masayuki Amagai, Takamitsu Hosoya, Katsuyuki Shiroguchi, Osamu Ohara. HaloTag-based conjugation of proteins to barcoding-oligonucleotides. Nucleic acids research. 2020. 48. 2. e8
  • Nishiyama T, Kobayashi T, Jirintai S, Kii I, Nagashima S, Prathiwi Primadharsini P, Nishizawa T, Okamoto H. Screening of novel drugs for inhibiting hepatitis E virus replication. Journal of virological methods. 2019. 270. 1-11
  • Komura H, Kakio S, Sasahara T, Arai Y, Takino N, Sato M, Satomura K, Ohnishi T, Nabeshima YI, Muramatsu SI, Kii I, Hoshi M. Alzheimer Aβ Assemblies Accumulate in Excitatory Neurons upon Proteasome Inhibition and Kill Nearby NAKα3 Neurons by Secretion. iScience. 2019. 13. 452-477
  • Yoshida S, Kuribara T, Ito H, Meguro T, Nishiyama Y, Karaki F, Hatakeyama Y, Koike Y, Kii I, Hosoya T. A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach. Chemical communications (Cambridge, England). 2019. 55. 24. 3556-3559
  • Kii I. Periostin Functions as a Scaffold for Assembly of Extracellular Proteins. Advances in experimental medicine and biology. 2019. 1132. 23-32
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MISC (26):
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Lectures and oral presentations  (62):
  • Staudinger反応を利用した安定なアザイリドの形成に基づく分子連結法の開発
    (第44回有機典型元素化学討論会 2017)
  • Duchenne型筋ジストロフィーに対して変異ジストロフィンエキソンのスキッピング誘導活性を有する経口投与可能な新規CLK1阻害剤の開発
    (2017年度生命科学系学会合同年次大会 2017)
  • がん細胞の代謝がもたらす組織微小環境を標的にしたがん治療
    (2017年度生命科学系学会合同年次大会 2017)
  • 神経新生促進によるダウン症モデルにおける脳発達障害の是正
    (2017年度生命科学系学会合同年次大会 2017)
  • Sequential Multicolor Pulse-Chase Imaging of Protein Dynamics in Extracellular Matrix in Living Fibroblasts
    (The 4th RIKEN/Karolinska Institute/SciLifeLab Joint Symposium 2017)
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Education (3):
  • 2002 - 2005 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
  • 2000 - 2002 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
  • 1996 - 2000 Tokyo Institute of Technology School of Bioscience and Biotechnology
Work history (9):
  • 2020/04 - 現在 Shinshu University
  • 2019/04 - 2020/03 Shinshu University
  • 2018/04 - 2019/03 RIKEN Unit Leader
  • 2017/01 - 2018/03 RIKEN Unit Leader
  • 2016/04 - 2016/12 RIKEN CLST Senior Scientist
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Awards (2):
  • 2009 - The 3rd Mechanobiology Workshop. National University of Singapore Travel Fellowship
  • 2004 - 26th Annual Meeting of the American Society for Bone and Mineral Research. Seattle, Washington, USA Young Investigator Award
Association Membership(s) (4):
International Chemical Biology Society ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  JAPANESE SOCIETY FOR CHEMICAL BIOLOGY
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