Rchr
J-GLOBAL ID:200901033023282325   Update date: Oct. 02, 2020

Hirano Katsuya

ヒラノ カツヤ | Hirano Katsuya
Affiliation and department:
Homepage URL  (1): http://www.med.kagawa-u.ac.jp/~cardiovasc-physiol
Research field  (3): Cardiology ,  Pharmacology ,  Physiology
Research keywords  (8): 細胞内シグナル伝達 ,  循環器 ,  病態生理学 ,  生理学 ,  Intracellular signal transduction ,  Cardiovascular system ,  Pathophysiology ,  Physiology
Research theme for competitive and other funds  (27):
  • 2020 - 2023 凝固系を標的とした高齢者のインスリン抵抗性改善策の開発
  • 2016 - 2019 トロンビン受容体を標的とする新規肺高血圧治療法の開発
  • 2015 - 2018 プロテイナーゼ活性化型受容体1を介する血管機能障害の分子機構解明
  • 2014 - 2016 トロンビン受容体を標的とする核心的脳血管攣縮治療法の開発
  • 2012 - 2015 トロンビン受容体の活性制御異常の分子機構解明と新たな動脈硬化治療戦略の開発
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Papers (173):
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MISC (140):
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Patents (4):
  • A therapeutic agent and a preventive agent for pulmonary hypertension comprising thrombin receptor antagonist as an active ingredient
  • プロテアソーム分解に抵抗性を示す新規p27Kip1分子種の核酸及びアミノ酸配列と同蛋白質の発現ベクター及び発現細胞
  • トロンビン受容体アンタゴニストを有効成分とするくも膜下出血に伴う血管攣縮の治療剤
  • Nucleic acid and amino acid sequences of the degradation-resistant novel isoform of p27Kip1, and expression plasmid and cells expressing the protein
Books (8):
  • The unique property of the pulmonary artery regarding the smooth muscle effects of proteinase-activated receptor 1: The possible contribution to the pathogenesis of pulmonary hypertension.
    Springer, Tokyo, Japan 2017
  • The unique property of the pulmonary artery regarding the smooth muscle effects of proteinase-activated receptor 1: The possible contribution to the pathogenesis of pulmonary hypertension.
    Springer, Tokyo, Japan 2017
  • Measurement of [Ca2+]i in smooth muscle strips using front-surface fluorimetry.
    Humana Press, New York, 2013 ISBN:9781627030854
  • Measurement of [Ca2+]i in smooth muscle strips using front-surface fluorimetry.
    Humana Press, New York, 2013 ISBN:9781627030854
  • Idendification of hydrogen peroxide as an endothelium-derived hyperpolarization factor in mice.
    Taylor & Francis, London, UK 2001
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Lectures and oral presentations  (120):
  • Novel role of coagulation factor XI as a regulator of vascular smooth muscle function.
    (The 9th Federation of the Asian and Oceanian Physiological Society Congress (FAOPS2019) 2019)
  • Proteinase-activated receptor 1 (PAR1)-mediated cellular effects of coagulation factor XI in vascular smooth muscle cells
    (2019)
  • 血管平滑筋細胞において凝固第XI因子はトロンビン受容体PAR1を活性化し、細胞内Ca2+シグナルを発生させ、細胞遊走を促進する
    (第48回日本心脈管作動物質学会総会 2019)
  • トロンビンによる内皮バリアー機能障害の初期事象におけるRho-Rhoキナーゼの役割
    (第59回日本脈管学会総会 2018)
  • Novel function of coagulation factor XI as a regulator of vascular smooth muscle
    (The 7th Chiang Mai University-Kagawa University Joint Symposium 2018 2018)
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Works (1):
  • 日本平滑筋学会ロゴマークデザイン
    2014 - 現在
Education (2):
  • 1991 - Kyushu University
  • 1979 - 1985 Kyushu University School of Medicine
Professional career (1):
  • M. D., Ph.D. (Kyushu University)
Work history (9):
  • 2014/04 - Kagawa University, Faculty of Medicine Department of Cardiovascular Physiology Professor
  • 2006/08 - 2014/03 Kyushu University, Graduate School of Medicine Department of Molecular Cardiology Associate Professor
  • 2000/04 - 2006/07 Kyushu University, Graduate School of Medicine Department of Molecular Cardiology Assistant professor, Lecturer
  • 1999/04 - 2000/03 Kyushu University, Graduate School of Medicine Department of Molecular Cardiology Assistant professor, Lecturer
  • 1996/11 - 1999/03 Kyushu University, Faculty of Medicine Department of Molecular Cardiology Assistant professor, Lecturer
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Committee career (35):
  • 2020/08 - 現在 Japan Society of Smooth Muscle Research The president of the 63rd Annual Meeting of Japan Society of Smooth Muscle Research
  • 2020/03 - 現在 Physiological Society of Japan Vice President
  • 2019/11 - 現在 Physiological Society of Japan member of the committee for meetings
  • 2018/03 - 現在 日本生理学会 理事
  • 2018/03 - 現在 Physiological Society of Japan Member of the committee for Awards
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Awards (8):
  • 2020/03 - Japanese Pharmacological Society Journal of Pharmacological Sciences Excellent Reviewer Award 2019
  • 2017/03 - Japanese Pharmacological Society Journal of Pharmacological Sciences Excellent Reviewer Award 2016
  • 2014/08 - Japan Society of Smooth Muscle Research Gold medal of logo mark design
  • 2013 - 第29回スパズム・シンポジウム 第4回優秀論文賞
  • 2011 - 第27回スパズム・シンポジウム 第2回優秀論文賞
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Association Membership(s) (11):
日本循環薬理学会 ,  日本病態生理学会 ,  国際心臓研究学会 ,  日本平滑筋学会 ,  日本心脈管作動物質学会 ,  日本生理学会 ,  日本分子生物学会 ,  日本内科学会 ,  日本循環器学会 ,  American Heart Association ,  日本薬理学会
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