Yoshida Minoru

ヨシダミノル | Yoshida Minoru

Affiliation and department：
Job title： Executive Director
Other affiliations (1)：

Homepage URL (1)： http://www.riken.jp/SPD/CG/index.html

Research field (2)： Applied molecular and cellular biology , Applied biochemistry

Research keywords (5)： Applied Microbiology , 化学遺伝子 , 化学生物学 , Chemical Genetics , Chemical Biology

Research theme for competitive and other funds (64)：

2023 - 2028 Chemical genetic approach to mode of action and biological validation of compounds from latent chemical space
2023 - 2028 天然物が織り成す化合物潜在空間が拓く生物活性分子デザイン
2022 - 2024 Utilization of an energy metabolic control compound to treat mitochondrial diseases
2021 - 2024 ミトコンドリア病治療法確立を目指したエネルギー代謝の化学的制御研究
2021 - 2023 Studies on functional and chemical diversity of siderophores produced by filamentous fungi

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Papers (442)：

Mayuki Sasaki, Shinichi Nishimura, Akihisa Matsuyama, Minoru Yoshida. Protocol for detecting threonine deaminase activity in fission yeast cell lysates. STAR Protocols. 2023. 4. 4. 102675-102675
Naoto Yoshinaga, Takaaki Miyamoto, Masaki Odahara, Noriko Takeda-Kamiya, Kiminori Toyooka, Seia Nara, Haruna Nishimura, Feng Ling, Masayuki Su'etsugu, Minoru Yoshida, et al. Design of an Artificial Peptide Inspired by Transmembrane Mitochondrial Protein for Escorting Exogenous DNA into the Mitochondria to Restore their Functions by Simultaneous Multiple Gene Expression. Advanced Functional Materials. 2023. 34. 8
Miki Kato, Keisuke Maeda, Ryuichi Nakahara, Haruka Hirose, Ayano Kondo, Sho Aki, Maki Sugaya, Sana Hibino, Miyuki Nishida, Manami Hasegawa, et al. Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils. PNAS nexus. 2023. 2. 10. pgad306
Jing Yan, Hengsen Zhang, Yuna Tomochika, Bin Chen, Yashuang Ping, Md. Shoriful Islam, Shuhei Aramaki, Tomohito Sato, Yu Nagashima, Tomohiko Nakamura, et al. UBL3 Interaction with α-Synuclein Is Downregulated by Silencing MGST3. Biomedicines. 2023. 11. 9. 2491-2491
Kali R Iyer, Sheena C Li, Nicole M Revie, Jennifer W Lou, Dustin Duncan, Sara Fallah, Hiram Sanchez, Iwona Skulska, Mojca Mattiazzi Ušaj, Hamid Safizadeh, et al. Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity. Cell chemical biology. 2023. 30. 7. 795-810

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MISC (199)：

Ken Matsumoto, Minoru Yoshida. Mammalian Chemical Genomics towards Identifying Targets and Elucidating Modes-of-Action of Bioactive Compounds. ChemBioChem. 2022. 23. 7
岩崎信太郎, 岩崎信太郎, 吉田稔, 吉田稔, 吉田稔. Splicing modulation-mediated translational control. 生化学. 2022. 94. 6
天野日菜子, 平中誠弥, 式田亮史, 中田明子, 新真由美, 工藤紀雄, 伊藤孝, 伊藤昭博, 吉田稔, 布村一人, et al. Discovery of pyrilamine derivatives as isozyme-selective histone deacetylase 6 inhibitors. メディシナルケミストリーシンポジウム講演要旨集. 2022. 39th (CD-ROM)
Tilman Schneider-Poetsch, Jagat Krishna Chhipi-Shrestha, Minoru Yoshida. Splicing modulators: on the way from nature to clinic. The Journal of Antibiotics. 2021
小林大貴, 吉田稔. 機能低下したミトコンドリアを活性化させる化合物の発見. 実験医学. 2021. 39. 6. 954-957

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Patents (25)：

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Books (30)：

ケミカルバイオロジー化合物集 -研究展開のヒント-
オーム社 2018 ISBN:9784274507090
Advances in Industrial Applications of Yeasts, Koji-molds, and Lactic Acid Bacteria
2018
Bioprobes: Biochemical Tools for Investigating Cell Function
Springer 2017
エピジェネティクス実験スタンダード (実験医学別冊)
2017
生物活性分子のケミカルバイオロジー標的同定と作用機構
化学同人 2015

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Lectures and oral presentations (1,047)：

細胞膜透過性向上を志向したヒドロキサム酸構造を有するpyrilamine型HDAC6阻害剤の探索合成
(日本薬学会144年会 2028)
ホスホフルクトキナーゼ-1阻害剤トリプトリナミドの高活性異性体の絶対配置同定
(日本薬学会144年会 2024)
酵母から哺乳類まで寿命を延ばす細菌
(日本農芸化学会2024年度大会 2024)
グルタチオンは分裂酵母の栄養制御に関わる細胞間コミュニケーション分子である
(日本農芸化学会2024年度大会 2024)
別府輝彦先生の至言と微生物ケミカルバイオロジー
(日本農芸化学会2024年度大会 2024)

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Professional career (1)：

Work history (10)：

2023/04 - 現在 RIKEN Executive Director
2023/04 - 現在 Distinguished Professor of The University of TOKYO
2013/04 - 現在 RIKEN Center for Sustainable Resource Science Chemical Genomics Research Group Group Director
2022/04 - 2023/03 RIKEN Research Strategy Advisor
2017/04 - 2023/03 The University of Tokyo Graduate School of Agricultural and Life Sciences Professor

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Committee career (64)：

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Awards (13)：

2022/11 - Person who has made outstanding cultural contributions
2018/12 - Cabinet Secretariat, Office of Healthcare Policy The Japan Medical Research and Development Grand Prize, the Healthcare Policy Minister's Prize Basic studies on molecular target drug discovery based on epigenetic regulation
2018/04 - 公益財団法人長瀬科学技術振興財団長瀬研究振興賞新規抗真菌抗生物質 ASP2397 の作用機序に関する化学遺伝学的研究
2017/02 - Princess Takamatsu Cancer Research Fund Princess Takamatsu Cancer Research Fund Prizes Chemical biology on cancer therapy targeting regulatory molecules of epigenetics
2015/06 - The Japan Academy Japan Academy Prize Studies on Regulation of Eukaryotic Gene Expression using Bioactive Microbial Metabolites and their Application to Drug Discovery

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Association Membership(s) (6)：

日本癌学会 , 日本分子生物学会 , 日本生化学会 , 日本農芸化学会 , JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER

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