Rchr
J-GLOBAL ID：200901033490787350   Update date: Sep. 25, 2024

Mashima Tetsuo

マシマ テツオ | Mashima Tetsuo
Affiliation and department：
Japanese Foundation for Cancer Research Cancer Chemotherapy Center, Molecular Biotherapy Research

About Japanese Foundation for Cancer Research Cancer Chemotherapy Center, Molecular Biotherapy Research


Job title： Researcher
Homepage URL  (1)： https://scholar.google.com/citations?user=Yq7ZvtsAAAAJ&hl=en
Research field  (1)： Molecular biology
Research keywords  (19)： Drug-tolerant persister ,  drug resistance ,  cellular plasticity ,  cancer stemness ,  ALDH1A3 ,  Aldehyde dehydrogenase ,  Tankyrase ,  Wnt pathway ,  gastric cancer, colorectal cancer ,  patient-derived cells ,  Transcriptome analysis ,  molecular biomarker ,  molecular target screening ,  transrational research ,  VEGF receptor inhibitor ,  apoptosis ,  metabolic enzyme ,  prostate cancer ,  IL4I1/L-aimino acid oxidase
Research theme for competitive and other funds  (26)：
  • 2022 - 2028 先端モデル動物支援プラットフォーム
  • 2023 - 2025 Development of novel reprogramming therapy with tankyrase inhibitors by dual targeting of cancer microenvironment and stemness
  • 2021 - 2024 大腸癌治療薬の基礎解析データからの血中循環バイオマーカー同定と生物学的意義の解析
  • 2021 - 2024 胃がんの初期薬剤抵抗性を司るがん細胞の可塑性および安定維持機構の解明
  • 2022 - 分子プロファイリング支援活動・トランスクリプトーム解析
Show all
Papers (73)：
  • Mitsukuni Suenaga, Tetsuo Mashima, Naomi Kawata, Shingo Dan, Hiroyuki Seimiya, Kensei Yamaguchi. Exploratory Study Identifies Matrix Metalloproteinase;as Potential Biomarkers of Regorafenib;Efficacy in;Metastatic Colorectal Cancer. Cancers. 2024. 16. 16. 2855
  • Ryo Yanagiya, Yuji Miyatake, Natsumi Watanabe, Takanobu Shimizu, Akane Kanamori, Masaya Ueno, Sachiko Okabe, Joaquim Carreras, Shunya Nakayama, Ami Hasegawa, et al. Amino acid influx via LAT1 regulates iron demand and sensitivity to PPMX-T003 of aggressive natural killer cell leukemia. Leukemia. 2024. 38. 8. 1731-1741
  • Ayane Nakamura, Tetsuo Mashima (corresponding author), Jin Lee, Saori Inaba, Naomi Kawata, Shun Morino, Koshi Kumagai, Kensei Yamaguchi, Hiroyuki Seimiya (corresponding). Intratumor transforming growth factor-β signaling with extracellular matrix-related gene regulation marks chemotherapy-resistant gastric cancer. Biochemical and biophysical research communications. 2024. 721. 150108-150108
  • Jin Lee, Tetsuo Mashima (corresponding author), Naomi Kawata, Noriko Yamamoto, Shun Morino, Saori Inaba, Ayane Nakamura, Koshi Kumagai, Takeru Wakatsuki, Kengo Takeuchi, et al. Pharmacological targeting of histone H3K27 acetylation/BRD4-dependent induction of ALDH1A3 for early-phase drug tolerance of gastric cancer. Cancer research communications. 2024
  • Shiho Hirose, Tetsuo Mashima, Xunmei Yuan, Makiko Yamashita, Shigehisa Kitano, Shinichi Torii, Toshiro Migita, Hiroyuki Seimiya. Interleukin-4 induced 1-mediated resistance to an immune checkpoint inhibitor through suppression of CD8+ T cell infiltration in melanoma. Cancer Science. 2024
ｍore...
MISC (39)：
ｍore...
Patents (5)：
Education (3)：
  • - 1997 The University of Tokyo
  • - 1992 The University of Tokyo Faculty of Pharmaceutical Sciences
  • 1985 - 1988 私立武蔵高校
Professional career (1)：
  • (BLANK)
Work history (3)：
  • 2014 - 現在 Japanese Foundation for Cancer Research Cancer Chemotherapy Center
  • 1997/11 - 1998 医薬品副作用被害救済研究振興調査機構 派遣研究員(PD、東大分生研)
  • 1996/04 - 1997/10 日本学術研究会 特別研究員(DC2、東大分生研・鶴尾研究室)
Committee career (5)：
  • 2012/01 - 現在 Japanese Cancer Association councilor
  • Pharmaceutical Society of Japan Editor, Biol. Pharm. Bull
  • JFCR-ISCC Symposium Committee Member
  • 日本癌分子標的治療学会 選挙管理委員
  • 日本癌分子標的治療学会 評議員
Awards (2)：
  • 2007 - 日本がん分子標的治療学会研究奨励賞
  • 2007 - 日本癌学会奨励賞
Association Membership(s) (4)：
日本薬学会 ,  日本分子標的治療学会 ,  日本分子生物学会 ,  日本癌学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM