Kukimoto Iwao

クキモトイワオ | Kukimoto Iwao

Affiliation and department：
Job title： Head

Research field (3)： Molecular biology , Obstetrics and gynecology , Virology

Research keywords (6)： cervical cancer , molecular phylogeny , Viral carcinogenesis , APOBEC , Genomics , Human papillomavirus

Research theme for competitive and other funds (18)：

2023 - 2026 Elucidation of biological differences exhibited by HPV genomes uniquely detected in the Japanese population
2022 - 2026 HPVワクチン接種後の血清抗体:発症予防抗体価と持続期間の検討
2020 - 2024 HPVワクチンの有効性:ブレイクスルー症例の解析
2020 - 2023 ホスホイノシチド動態制御を介したヒトパピローマウイルス潜伏感染機構の解明
2019 - 2022 思春期女性へのHPVワクチン公費助成開始後における子宮頸癌のHPV16/18陽性割合の推移に関する疫学研究

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Papers (91)：

Eri Yoshiizumi, Mamiko Onuki, Iwao Kukimoto, Fumiaki Takahashi, Tomoya Matsui, Kyoko Hamasaki, Hiroyuki Kanao, Ai Nio, Hideaki Yahata, Mayuko Goda, et al. Declining Prevalence of Human Papillomavirus Co-Infections Among Young Japanese Women With Cervical Cancer and Its Precursors. Journal of medical virology. 2024. 96. 12. e70096
Yoshiyuki Ishii, Seiichiro Mori, Takamasa Takeuchi, Iwao Kukimoto. Differential requirement of the transcription factor HOXC13 for the stable maintenance of human papillomavirus genome among high-risk genotypes. Virology. 2024. 597. 110151-110151
Rie Kawasaki, Iwao Kukimoto, Tetsuya Tsukamoto, Eiji Nishio, Aya Iwata, Takuma Fujii. Cervical mucus can be used for metabolite screening in cervical cancer. Cancer Science. 2024
Takuma Fujii, Eiji Nishio, Tetsuya Tsukamoto, Iwao Kukimoto, Aya Iwata. Performance of an ancillary test for cervical cancer that measures miRNAs and cytokines in serum and cervical mucus. Cancer Science. 2024
Takeji Mitani, Iwao Kukimoto, Tetsuya Tsukamoto, Hiroyuki Nomura, Takuma Fujii. A prospective clinical trial of diathermy ablation for patients with high-grade cervical intraepithelial neoplasia from a single institution in Japan. Sci Rep. 2024. 14. 2632

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MISC (49)：

小貫麻美子, 渡利英道, 島田宗昭, 藤原寛行, 佐藤豊実, 吉田裕之, 横田治重, 岩田卓, 石川光也, 金尾祐之, et al. 我が国におけるHPVワクチンの直接予防効果と集団免疫効果 MINTスタディ10年の軌跡. 日本産科婦人科学会雑誌. 2022. 74. 臨増. S-463
關路晟, 李瑩芳, 西山智明, 大日輝記, 柊元巌, 若江亨祥, 村松正道. インターフェロンに誘導のAPOBEC3Bはメルケル細胞ウイルスゲノムに変異を導入する. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-898]
小谷燦璃古, 柊元巌, 野村弘行, 川原莉奈, 藤井多久磨. 子宮頸がんに高発現するmiRNAの検出法は補助診断として有効である. 日本癌学会総会記事. 2021. 80回. [P3-3]
小暮剛太, 小貫麻美子, 岩田卓, 松本光司, 柊元巌. 日本人女性から分離されたHPV67の全ゲノム解析. 日本癌学会総会記事. 2021. 80回. [P3-4]
若江亨祥, 柊元巌. APOBEC3はメルケル細胞ウイルスゲノムに変異を導入する. 日本癌学会総会記事. 2021. 80回. [P3-1]

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Lectures and oral presentations (7)：

Intra-Patient Variation of Human Papillomavirus Genome Contributing to Cervical Cancer Development
(The Joint 24th International Conference on Emerging Infectious Diseases in the Pacific Rim of the U.S.-Japan Cooperative Medical Sciences Program 2024)
Genome analysis of oncogenic human papillomaviruses infecting Japanese women
(2023)
APOBEC mutagenesis associated with human papillomavirus carcinogenesis
(2022)
Molecular epidemiology of high-risk HPV infection in Japan
(U.S.-Japan Cooperative Medical Sciences Program, Cancer Panel Meeting 2020)
Human Papillomavirus Carcinogenesis Mediated by APOBEC Mutagenesis
(2018)

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Education (2)：

Professional career (1)：

Work history (3)：

2007/04 - 現在 National Institute of Infectious Diseases Pathogen Genomics Center Lab head
1996/04 - 2007/03 National Institute of Infectious Diseases Pathogen Genomics Center
2001/07 - 2003/06 Marie Curie Research Institute Postdoctoral fellow

Association Membership(s) (6)：

日本環境変異原ゲノム学会 , International Papillomavirus Society , 日本生化学会 , 日本ウイルス学会 , 日本癌学会 , THE PHARMACEUTICAL SOCIETY OF JAPAN

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