Rchr
J-GLOBAL ID：200901033948533654
Update date: Oct. 25, 2021
TSUBOI Isao
ツボイ イサオ | TSUBOI Isao
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Anatomy
Research keywords (2)：
Aging
, hematopoiesis
Papers (87)：
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63.Harada T, Tsuboi I, Utsunomiya M, Yasuda M, Aizawa S. Kinetics of leukemic cells in 3D culture with stromal cells and with arginine deprivation stress. J Biosci Bioeng. 2020. 130. 650-658
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Tsuboi I, Harada T, Hirabayashi Y, Aizawa S. Dynamics of hematopoiesis is disrupted by impaired hematopoietic microenvironment in a mouse model of hemophagocytic lymphohistiocytosis. Ann Hematol. 2020. 99. 1515-1523
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Isao Tsuboi, Tomonori Harada, Yoko Hirabayashi, Shin Aizawa. Senescence-accelerated mice (SAMP1/TA-1) treated repeatedly with lipopolysaccharide develop a condition that resembles hemophagocytic lymphohistiocytosis. Haematologica. 2019. 104. 10. 1995-2005
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Nakagawa M, Uno S, Iriyama N, Matsunawa M, Makishima M, Takeuchi J, Tsuboi I, Hatta Y, Takei M. Combined treatment with benzopyrene and 1α, 25-dihydroxyvitamin D3 induces expression of plasminogen activator inhibitor 1 in monocyte/macrophage-derived cells. Toxicol Appl Pharmacol. 2018. 345. 48-56
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Kosaku K, Harada T, Jike T, Tsuboi I, Aizawa S. Long-term hypoxia in murine cornea. High Alt Med Biol. 2018. 19. 35-41
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MISC (1)：
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Fukino N, Harada T, Tsuboi I, Fukui S, Yasuda M, Aizawa S. In vitro chemosensitivity study of human leukemic cells in a three-dimensional bone marrow culture system. J Hematol Ther. 2016. 1. 7-15
Books (3)：
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Age-related functional impairment in the hematopoietic microenvironment induces vicious suppressive homeostasis in B lymphopoiesis in SAMP1 mice In: Takeda T et al. (eds.) The senescence-accelerated mouse (SAM): Achievements and Future Directions.
Amsterdam, Elsevier 2013
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Connexin 32(Cx32) plays double functions a promotion and a protection, for the chemically induced leukemogenesis
Molecular mechanisms of radiation-induced cellular response and cancer development . Institute for environment science 2002
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Age-related changes in hemopoietic system in SAM-P(TA-1) mice. In Takeda T.(Eds) The SAM Model Senescence. International Congress Series
Excerpta Medica 1994
Lectures and oral presentations (74)：
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LPS投与による血球貪食性リンパ組織球症様病態像モデルマウス
(第125回日本解剖学会総会・全国学術集会 2020)
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Senescence-accelerated mice (SAMP1/TA-1) treated repeatedly with LPS shows hemophagocytic lymphohistiocytosis-like disease.
(The 81Annual meeting of the Japanese society of hematology 2019)
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LPS頻回投与によりSAMP1/TA-1マウスは血球貪食性リンパ組織球症様病像を呈する
(第34回老化促進モデルマウス(SAM)学会学術大会 2019)
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Chemosensitivity study in a model of stimulated bone marrow :three-dementional culture system.
(2018)
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三次元培養法における白血病細胞の動態
(第123回日本解剖学会総会・全国学術集会 2018)
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Education (2)：
- - 1986 Nihon University Graduate School, Division of Medicine Post graduate school
- - 1982 Nihon University Faculty of Medicine Medicine
Committee career (3)：
- 2016/04 - 現在 老化促進モデルマウス学会 評議員
- 2015/04 - 現在 日本解剖学会 代議員
- 2015/04 - 現在 日本基礎老化学会 評議員
Awards (2)：
- 2014 - The Phamaceutical Society of Japan Highlighted paper selected by editor-in-chief of Biological and Pharmaceutical Bulletin
- 2012 - Society of Experimental Biology and Medicine Best paper award of the Society of Experimental Biology and Medicine
Association Membership(s) (5)：
老化促進モデルマウス学会
, 日本内科学会
, 日本血液学会
, 日本基礎老化学会
, 日本解剖学会
