Rchr
J-GLOBAL ID:200901034075513062   Update date: Oct. 25, 2024

Ryoko Shimizu

シミズ リョウコ | Ryoko Shimizu
Affiliation and department:
Job title: Senior Assistant Professor (Non-tenured)/Assistant Professor (Non-tenured)
Research field  (3): Metabolism and endocrinology ,  Nephrology ,  Cardiology
Research keywords  (1): extracellular matrix
Research theme for competitive and other funds  (11):
  • 2024 - 2026 Elucidation of the mechanisms of embryo-endometrial interactions induced by cell death
  • 2023 - 2026 the role of Hippo pathway in the pathogenesis of acute aortic dissection
  • 2022 - 2025 リシルオキシダーゼによる血管平滑筋細胞脱分化が大動脈解離発症に与える影響の検討
  • 2022 - 2025 Mechanism of blastocyst invasion controlled by uterine factors
  • 2022 - 2024 Development of a new diagnostic method for implantation failure using cervical cells
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Papers (44):
  • Shizu Aikawa, Mitsunori Matsuo, Shun Akaeda, Yukihiko Sugimoto, Makoto Arita, Yosuke Isobe, Yuki Sugiura, Shu Taira, Rae Maeda, Ryoko Shimizu-Hirota, et al. Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice. JCI Insight. 2024. 9. 19. e181865
  • Akihito Hishikawa, Erina Sugita Nishimura, Norifumi Yoshimoto, Ran Nakamichi, Eriko Yoshida Hama, Wataru Ito, Tomomi Maruki, Kengo Nagashima, Ryoko Shimizu-Hirota, Hiromasa Takaishi, et al. Predicting exacerbation of renal function by DNA methylation clock and DNA damage of urinary shedding cells: a pilot study. Scientific Reports. 2024. 14. 1
  • Maria Sunouchi, Jun Inaishi, Ryoko Shimizu-Hirota, Yoshifumi Saisho, Kaori Hayashi, Hiromasa Takaishi, Hiroshi Itoh. Longitudinal changes in pancreatic volume and pancreatic fat with weight gain in Japanese without diabetes: An analysis using health check-up data. Metabolism open. 2023. 19. 100250-100250
  • Yamato Fukui, Yasushi Hirota, Shizu Aikawa, Akihiko Sakashita, Ryoko Shimizu-Hirota, Norihiko Takeda, Chihiro Ishizawa, Rei Iida, Tetsuaki Kaku, Tomoyuki Hirata, et al. The EZH2-PRC2-H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasion. Cell death & disease. 2023. 14. 5. 320-320
  • Takehiro Hiraoka, Yasushi Hirota, Shizu Aikawa, Rei Iida, Chihiro Ishizawa, Tetsuaki Kaku, Tomoyuki Hirata, Yamato Fukui, Shun Akaeda, Mitsunori Matsuo, et al. Constant activation of STAT3 contributes to the development of adenomyosis in females. Endocrinology. 2022
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MISC (20):
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Books (1):
  • 実践臨床生殖免疫学
    中外医学社 2018 ISBN:9784498060883
Lectures and oral presentations  (62):
  • F4/80陽性マクロファージによるマウス分娩後子宮の老化細胞除去と次回妊娠に及ぼす影響
    (2017年生命科学系合同年次大会 2017)
  • 好中球由来MMP9が急性大動脈解離を誘発する
    (日本内分泌学会 2015)
  • 好中球由来MMP9を介した大動脈解離の発症機構
    (日本高血圧学会 2013)
  • 好中球由来MMPを介した大動脈解離の発症機構
    (日本病態プロテアーゼ学会 2013)
  • MMPを介した大動脈解離の発症機構
    (日本血管生物医学会 2013)
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Education (2):
  • 2002 - 2002 Keio University Graduate School, Division of Medicine Internal Medicine
  • 1998 - 1998 Keio University Faculty of Medicine
Professional career (1):
  • M.D., Ph.D. (Keio University)
Work history (8):
  • 2020/09 - 現在 Keio University School of Medicine Center for Preventive Medicine
  • 2012/08 - 現在 慶應義塾大学病院予防医療センター 助教
  • 2007/09 - 2012 ミシガン大学内科分子遺伝学教室 研究員
  • 2005/06 - 2007/08 慶應義塾大学医学部 救急医学助手
  • 2004/06 - 2005/03 慶應義塾大学病院 救急部専修医
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Committee career (22):
  • 日本腎臓学会 Member
  • 日本高血圧学会 Member
  • 日本透析学会 Member
  • 日本内科学会 Member
  • 日本循環器学会 Member
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Awards (10):
  • 2005/01 - 循環器学研究振興財団 循環器学研究振興財団研究奨励金
  • 2005/01 - 循環器学研究振興財団 循環器学研究振興財団研究奨励金
  • 2004/11 - 日本心臓財団 第30回日本心臓財団研究奨励金
  • 2004/11 - 日本心臓財団 第30回日本心臓財団研究奨励金
  • 2004/09 - 東京高血圧研究会 東京高血圧研究会優秀演題奨励賞
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Association Membership(s) (4):
日本高血圧学会 ,  日本内科学会 ,  日本内分泌学会 ,  日本人間ドック学会
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